Results 121 to 130 of about 570,434 (333)

B cell-helping functions of gut microbial metabolites

Microbial Cell, 2016
Commensal microflora profoundly affects the host immune system. It has long been observed that commensal bacteria enhance antibody production in the host by producing antigens for B cell receptors (BCR) and ligands for Toll-like receptors (TLR).
Chang H. Kim
doaj   +1 more source

Serial Transfer of Antibody Producing Cells on the Chorioallantoic Membrane.

Experimental Biology and Medicine, 1963
SummarySerial transfer of foci on the CAM through at least 3 transfers is confirmed. Significant titers of antibody were found in a high percentage of recipient eggs 5 days after inoculation of spleen cells from an immunized chicken. The transfer of cells from the CAM of these eggs to other eggs resulted in development of foci, but the proportion of ...
E P, COHEN, J S, INGRAHAM, D W, TALMAGE
openaire   +2 more sources

Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10. [PDF]

, 1996
The mechanism by which the mammalian mother accepts the implanting fetus as an allograft remains unexplained, but is likely to be the result of a combination of factors.
Abrams, JS, Corry, DB, Fisher, SJ, Litton, MJ, Locksley, RM, Roth, I   +5 more
core   +1 more source

Binding of anti‐HLA class I antibody to endothelial cells produce an inflammatory cytokine secretory pattern [PDF]

, 2009
Eduardo Reyes‐Vargas, Igor Y. Pavlov, Thomas B. Martins, Jason J. Schwartz, Harry R. Hill, Julio C. Delgado   +5 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells

Cell Reports, 2019
Summary: Mechanisms that govern transcriptional regulation of inflammation in atherosclerosis remain largely unknown. Here, we identify the nuclear transcription factor c-Myb as an important mediator of atherosclerotic disease in mice.
Eric A. Shikatani, Rickvinder Besla, Sherine Ensan, Aditi Upadhye, Nadiya Khyzha, Angela Li, Takuo Emoto, Felix Chiu, Norbert Degousee, Joshua M. Moreau, Heather M. Perry, Danya Thayaparan, Henry S. Cheng, Shaun Pacheco, David Smyth, Hossein Noyan, Caleb C.J. Zavitz, Carla M.T. Bauer, Ingo Hilgendorf, Peter Libby, Filip K. Swirski, Jennifer L. Gommerman, Jason E. Fish, Martin R. Stampfli, Myron I. Cybulsky, Barry B. Rubin, Christopher J. Paige, Timothy P. Bender, Coleen A. McNamara, Mansoor Husain, Clinton S. Robbins   +30 more
doaj   +1 more source

Carrier and Hapten Antibody-Producing Cells, in Vitro I. Cytokinetics

Experimental Biology and Medicine, 1973
SummaryNormal spleen cells or HRBC-primed spleen cells were cultured with HRBC, TNP-HRBC or without an in vitro immunogen. Anti-HRBC and anti-TNP responses were assessed on Days 2, 3, and 4. Antibody-producing cells detected on Day 2 arose mainly from late, on Day 3 from intermediate and on Day 4 from early precursor cell types.
T L, Pazdernik, E M, Uyeki, J, Doull
openaire   +2 more sources

SPECIFICITY OF THE ANTIBODIES PRODUCED BY SINGLE CELLS FOLLOWING IMMUNIZATION WITH ANTIGENS BEARING TWO TYPES OF ANTIGENIC DETERMINANTS [PDF]

, 1967
Ira Green, P Vassalli, Victor Nussenzweig, Baruj Benacerraf   +3 more
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Single-cell antibody nanowells: a novel technology in detecting anti-SSA/Ro60- and anti-SSB/La autoantibody-producing cells in peripheral blood of rheumatic disease patients [PDF]

, 2016
Lida Esfandiary, Nirupama Gupta, Alexandria Voigt, Arun Wanchoo, Edward K. L. Chan, Sukesh Sukumaran, Cuong Q. Nguyen   +6 more
openalex   +1 more source