Results 171 to 180 of about 3,354,986 (307)

The transcription elongation factors Spt4 and Spt6 promote dermal adipocyte differentiation. [PDF]

Adipocyte
Gomez J, Mahapatra S, Batzorig U, Liu Y, Fernández-Méndez C, Quadir N, Sen GL.   +6 more
europepmc   +1 more source

Antibody engineering [PDF]

Nature Biotechnology, 2020
openaire   +2 more sources

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Serology survey against multiple SARS-CoV-2 variants of residents in Tainan, Taiwan. [PDF]

Virulence
Hsu IL, Du PX, Chou TM, Cheng CC, Tsai PS, Shih HC, Chen SC, Li CY, Ho TS, Syu GD.   +9 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Therapeutic efficacy of bovine ultra-long CDR H3 antibody against BVDV in challenged BALB/c mouse model. [PDF]

Front Immunol
Rile G, Zhao Q, Qi N, Wang B, Mei J, Wang H, Zhang S, Bao F.   +7 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Validation of TRPA1 and TRPV1 Antibodies for Expression Detection in Mammalian Cells and Tissues. [PDF]

J Neurochem
de Las Casas M, Hernández-Ortego P, Torres-Montero R, De la Peña E, Gomis A, Viana F, Fernández-Trillo J.   +6 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Alternative diagnoses in patients referred to neuroimmunology for autoimmune encephalitis evaluation. [PDF]

J Neurol
Damman SF, Rai SM, Shrestha R, Shaikh AG, Abboud H.   +4 more
europepmc   +1 more source