Results 221 to 230 of about 2,117,746 (268)
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Antibody Suppression and Antiallotype Antibodies
Scandinavian Journal of Immunology, 1976Antibody formation in rabbits against sheep erythrocytel (SRBC) was suppressed after injection of anti‐SRBC IgG. Suppression did not occur, however, if the injected IgG had an allotypic marker to which the rabbits possessed circulating antibody.
D, Jerne, B, Aasted
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Antiphospholipid antibody and antiphospholipid antibody syndrome
Current Opinion in Rheumatology, 1991New details have been added to the description of the antiphospholipid antibody syndrome. These include quantitation of risk of stroke; delineation of an associated acute occlusive vasculopathy syndrome, including its pathology; increased awareness of the association of adrenal insufficiency with antiphospholipid antibody; new demonstration of ...
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Advanced Drug Delivery Reviews, 2006
The clinical and commercial success of monoclonal antibodies has led to the need for very large-scale production in mammalian cell culture. This has resulted in rapid expansion of global manufacturing capacity [1], an increase in size of reactors (up to 20,000 L) and a greatly increased effort to improve process efficiency with concomitant ...
John R, Birch, Andrew J, Racher
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The clinical and commercial success of monoclonal antibodies has led to the need for very large-scale production in mammalian cell culture. This has resulted in rapid expansion of global manufacturing capacity [1], an increase in size of reactors (up to 20,000 L) and a greatly increased effort to improve process efficiency with concomitant ...
John R, Birch, Andrew J, Racher
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From antibodies to sperm to antibodies in transplantation
Urology, 1998a) To assess the use of "panning" procedures for the detection of antibodies to sperm. b) To develop and use human monoclonal antibodies for the analysis of human transplantation antigens."Panning" assays were developed. The procedures and their use in the analysis of mouse monoclonal antibodies to human sperm are described.
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Recombinant Antibodies for the Generation of Antibody Arrays
2011Affinity proteomics, mainly represented by antibody microarrays, has in recent years been established as a powerful tool for high-throughput (disease) proteomics. The technology can be used to generate detailed protein expression profiles, or protein maps, of focused set of proteins in crude proteomes and potentially even high-resolution portraits of ...
Carl A K, Borrebaeck, Christer, Wingren
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Journal of Infectious Diseases, 1981
Serologic reagents have played an important role in the diagnosis, treatment, and epidemiology of infectious diseases. A new technology has been developed for generating homogeneous antibodies that can be produced in large amounts and are available indefinitely. This technique promises to increase the reliability and sensitivity of immunoassays and may
M D, Scharff, S, Roberts, P, Thammana
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Serologic reagents have played an important role in the diagnosis, treatment, and epidemiology of infectious diseases. A new technology has been developed for generating homogeneous antibodies that can be produced in large amounts and are available indefinitely. This technique promises to increase the reliability and sensitivity of immunoassays and may
M D, Scharff, S, Roberts, P, Thammana
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Annual Review of Biomedical Engineering, 2000
Antibodies are unique in their high affinity and specificity for a binding partner, a quality that has made them one of the most useful molecules for biotechnology and biomedical applications. The field of antibody engineering has changed rapidly in the past 10 years, fueled by novel technologies for the in vitro isolation of antibodies from ...
J, Maynard, G, Georgiou
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Antibodies are unique in their high affinity and specificity for a binding partner, a quality that has made them one of the most useful molecules for biotechnology and biomedical applications. The field of antibody engineering has changed rapidly in the past 10 years, fueled by novel technologies for the in vitro isolation of antibodies from ...
J, Maynard, G, Georgiou
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Purification of Antibodies and Preparation of Antibody Fragments
2005Antibodies may be purified from serum, ascitic fluid, and tissue culture supernatant by a number of methods. Purified antibodies can be treated to produce fragments that may have enhanced properties for use in immunochemistry.
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Antiphospholipid antibodies and the antiphospholipid antibody syndrome
Journal of the American Academy of Dermatology, 1997The antiphospholipid antibody syndrome is a multiple-system disorder characterized by persistently elevated antiphospholipid antibodies and/or arterial or venous thrombosis, thrombocytopenia, or recurrent spontaneous abortion. Anticardiolipin antibodies and the lupus anticoagulant are different classes of antiphospholipid antibodies associated with ...
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Trends in Pharmacological Sciences, 1993
Hybridoma technology enabled rodent monoclonal antibodies to be created against human pathogens and cells, but these had limited clinical utility. Protein engineering, reviewed her by Greg Winter and William Harris, is now generating antibodies for treatment of infectious disease, autoimmune disease and cancer by 'humanizing' rodent antibodies ...
G, Winter, W J, Harris
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Hybridoma technology enabled rodent monoclonal antibodies to be created against human pathogens and cells, but these had limited clinical utility. Protein engineering, reviewed her by Greg Winter and William Harris, is now generating antibodies for treatment of infectious disease, autoimmune disease and cancer by 'humanizing' rodent antibodies ...
G, Winter, W J, Harris
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