Results 211 to 220 of about 2,398,894 (298)

Expression of antibody-drug conjugate targets in soft tissue sarcomas. [PDF]

ESMO Open
Bertucci F, Finetti P, Mescam L, Monneur A, Frejafon A, Le Cesne A, Treilleux I, Italiano A, Brahmi M, Blay JY, Mamessier E.   +10 more
europepmc   +1 more source

Ultrathin Hydrogel Membranes Inspired by Soap Films Enable Physiologically Relevant Breathing Lung Models

Advanced Materials, EarlyView.
A soap‐film inspired strategy enables the fabrication of ultrathin yet robust GelMA‐PAAm membranes for breathing lung culture. The hydrogel membrane supports long‐term cyclic deformation under air‐liquid interface conditions, enabling physiologically relevant breathing motions of engineered lung tissue culture. ABSTRACT Breathing continuously stretches
Yunji Lee, Gwang Myeong Kim, Wookyeom Kim, Fenny Soetanto, Gyungin Ryu, Taehun Chung, Youn Soo Kim, Junmin Lee, Hwa‐Rim Lee, Sungjune Jung   +9 more
wiley   +1 more source

Evolution of the NCI antibody-drug conjugate portfolio: from chemical engineering to clinical complexity. [PDF]

Front Med (Lausanne)
Zhan Q, Zeng W, Shi H, Wan H.
europepmc   +1 more source

Metal–Organic Framework‐Preserved Thermostable Microneedle Patch for Minimally Invasive Detection and Monitoring of Kidney Dysfunction

Advanced Materials, EarlyView.
By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang, Ying Liu, Avishek Debnath, Chuang Li, Zheyu Wang, Gayathri Kondepati, Saketh Balmoori, Jeremiah J. Morrissey, Ying Maggie Chen, Limei Tian, Srikanth Singamaneni   +10 more
wiley   +1 more source

Mechanism of uptake and toxicity of a BCMA antibody drug conjugate with a MMAF payload by nonantigen expressing cells. [PDF]

Cell Biol Toxicol
Newman C, Taylor C, Sohanpal G, Högg T, Kennedy J, McKinley E, Koudouna E, Sayers EJ, Jones AT, Watson P, Weir L.   +10 more
europepmc   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

A Patient-Led Survey of Antibody Drug Conjugate Usage and Dosing for People Living With Metastatic Breast Cancer. [PDF]

J Patient Exp
Beumer A, Carlson M, Arcuri AL, Maues J, Cowden J, Walker S, Shanahan K, Collins JL, Veach AJ, Rugo HS, Burkard ME, Kalinsky KM, Bardia A, Lustberg MB, Papautsky EL, Roberson ML.   +15 more
europepmc   +1 more source

Transient Cytoskeletal Anisotropy Encodes Short‐Term Mechanical Memory in Glioblastoma Cells

Advanced Materials, EarlyView.
The same mechanical deformation can produce distinct cytoskeletal states depending on loading history. Experiments and constitutive modeling reveal that transient actin–vimentin anisotropy stores mechanical information and governs short‐term mechanical memory in glioblastoma cells.
Clara Gomez‐Cruz, Matthieu Gelin, Lucas Pradeau‐Phélut, Arrate Muñoz‐Barrutia, Sandrine Etienne‐Manneville, Daniel Garcia‐Gonzalez   +5 more
wiley   +1 more source

Author Correction: SEZ6-targeting antibody-drug conjugate ABBV-706 in advanced small cell lung cancer and solid tumors: a phase 1 trial. [PDF]

Nat Med
Byers LA, Cho BC, Cooper AJ, Chiang AC, Han JY, Furqan M, Dowlati A, Morgensztern D, Papadopoulos KP, Choudhury NJ, Vieito M, Bar J, Kim JH, Akerley W, Kim TM, Kim YC, Paz-Ares L, Ahn MJ, Yokouchi H, Meiman D, Munasinghe W, Ogunyankin O, Jahchan N, Wang S, Ferlini C, Robinson RR, Kohlhapp FJ, Palenski T, Rivell G, Hingorani P, Chandana S.   +30 more
europepmc   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source