Results 161 to 170 of about 49,428 (256)

Pharmacokinetic and Pharmacodynamic Modeling of Antibody-Drug Conjugates. [PDF]

Cancers (Basel)
Glassman PM.
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

The role of antibody-drug conjugates in the treatment of lung cancer. [PDF]

Front Oncol
Zlatanova T, Changalova A, Janzic U.
europepmc   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Exatecan Payload-Based Antibody-Drug Conjugates with a Short Hydrophilic Cleavable Linker. [PDF]

ACS Med Chem Lett
Jammalamadaka V, Liu J, Bhakta S, Velupula S, Martha B, Jonnalagadda V, Junutula JR.   +6 more
europepmc   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Deruxtecan-based antibody-drug-conjugates induce senescence in HER2-positive breast cancer. [PDF]

Sci Rep
Vezzoli E, Pinos R, Galbiati S, Zambroni D, Dall'Ara C, Locatelli A, Colombo E, Galbardi B, Viganò L, Lavagnino Z, Scielzo C, De Palma C, Bianchini G, Tacchetti C, Daniele T.   +14 more
europepmc   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source

Multi-payload antibody-drug conjugates for photothermal dynamic and chemotherapy of HER2-positive breast cancer. [PDF]

Mater Today Bio
Zhang Y, Bai Y, Ren X, Fan Y, Lv Z, Song Q, Wang X, Shi H.   +7 more
europepmc   +1 more source