Results 361 to 370 of about 10,170,244 (414)

Microfluidic analysis of antibody specificity in a compact disk format.

Journal of Proteome Research, 2006
A new and flexible technology for high throughput analysis of antibody specificity and affinity is presented. The method is based on microfluidics and takes advantage of compact disks (CDs) in which the centrifugal force moves fluids through ...
Cecilia Eriksson, Charlotta Agaton, Rikard Kånge, Mårtenn Sundberg, P. Nilsson, B. Ek, M. Uhlén, M. Gustafsson, S. Hober   +8 more
semanticscholar   +1 more source

Simplified radioimmunoassay for serum aldosterone utilizing increased antibody specificity.

Journal of Clinical Endocrinology and Metabolism, 1974
A shortened, simplified radioimmunoassay for serum aldosterone has been made possible by the development of a highly specific antiserum for aldosterone.
J. McKenzie, J. Clements
semanticscholar   +1 more source

Specific anti-antibody in transplantation

Experientia, 1968
Durch ein immunologisches Dreieck-System (Hund-Kaninchen-Hund) wurde ein Anti-Antikorper bei Hunden erzeugt und seine Wirkung in vitro und in vivo demonstriert. Die Anti-Antikorper-Methode bietet neue Moglichkeiten, dem Problem der Transplantat-Abstossung und der Therapie der Krankheiten immunologischen Ursprungs naherzukommen.
E. T. Konno, F. A. Zydeck, N. Radoiu, Paul L. Wolf   +3 more
openaire   +3 more sources

Purification and specificity of antibodies to adenosine

Biochimie, 1977
Antibodies to adenosine were elicited in rabbits by immunization with bovine serum albumin-adenosine conjugate. The antibodies were purified and fractionated on two affinity columns (Sepharose-oligo(A) and Sepharose-AMP). Two families of antibodies have been obtained.
Marc Leng, Jacques Lavayre
openaire   +3 more sources

Engineering antibody affinity and specificity

International Journal of Cancer, 1988
A combination of ab initio calculations, "knowledge-based prediction", molecular graphics and site-directed mutagenesis has enabled us to probe the molecular details of antibody:antigen recognition and binding and to alter the affinity and specificity of an antibody for its antigen.
Anthony R. Rees, Sally Roberts, Janet Cheetham, D. M. Webster, R. Griest   +4 more
openaire   +2 more sources

Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning

Nature Biomedical Engineering, 2021
Derek M. Mason, Simon Friedensohn, Cédric R. Weber, Christian Jordi, Bastian Wagner, Simon M Meng, R. Ehling, Lucia Bonati, J. Dahinden, P. Gainza, B. Correia, S. Reddy   +11 more
semanticscholar   +1 more source

What is the antibody specificity of LATS?

Journal of Clinical Endocrinology and Metabolism, 1970
The immunoglobulin character of the LATS molecule demands an effort to find its antibody specificity. From studies correlating LATS activity measured by a modified Mc-Kenzie assay and antibody reactivities against thyroglobulin and thyroid cytoplasmic ...
A. Fagraeus, J. Jonsson, D. el-Kabir
semanticscholar   +1 more source

Anti-DNA Antibodies: Specificity?

Annals of Internal Medicine, 1973
Excerpt To the editor: I read with interest the review on recent advances in rheumatoid diseases (Ann Intern Med77:455-464, 1972).
openaire   +3 more sources

On the structure of a specific antibody site

Journal of Theoretical Biology, 1963
Abstract The specific combining region of an antibody molecule has been assumed to be a fixed property of the molecule. However, this assumption is unlikely if the antigen plays an instructive role in antibody formation. A simpler model of the specific site must be considered.
openaire   +3 more sources

Continuous cultures of fused cells secreting antibody of predefined specificity

Nature, 1975
G. Köhler, C. Milstein
semanticscholar   +1 more source