Results 171 to 180 of about 83,224 (354)

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

British Journal of Pharmacology, EarlyView.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen, Declan P. McKernan, John P. Kelly   +2 more
wiley   +1 more source

Anticholinergic Burden Measures Predict Older People's Physical Function and Quality of Life: A Systematic Review [PDF]

, 2020
Carrie Stewart, Kaisa R. Yrjana, Mitrysha Kishor, Roy L. Soiza, Martin Taylor‐Rowan, Terence J. Quinn, Yoon K. Loke, Phyo Kyaw Myint   +7 more
openalex   +1 more source

Rocuronium and Sugammadex Use Among Canadian Pediatric Anesthesiologists: A National Cross‐Sectional Survey

Pediatric Anesthesia, EarlyView.
MengQi Zhang, Jonathan G. Bailey, Tristan Dumbarton, Mathew B. Kiberd   +3 more
wiley   +1 more source

Association between glucagon‐like peptide‐1 receptor agonists and risk of dementia in older adults with type 2 diabetes: A target trial emulation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aim Type 2 diabetes (T2D) is associated with increased dementia risk, but comparative data across newer glucose‐lowering therapies remain limited. We examined whether the initiation of GLP‐1 receptor agonists (GLP‐1 RAs) was associated with incident dementia compared with DPP4 inhibitors (DPP4is) and SGLT2 inhibitors (SGLT2is) in older adults ...
Ting Zhou, Huilin Tang, Bingyu Zhang, Dazheng Zhang, Yiwen Lu, Lu Li, Jiajie Chen, Yong Chen, David A. Asch, Yong Chen   +9 more
wiley   +1 more source

ANTICHOLINERGIC PREMEDICATION

British Journal of Anaesthesia, 1980
R K, Mirakhur, J W, Dundee, J D, Connolly   +2 more
openaire   +2 more sources

Field‐applicable low‐intensity exercise induces bronchodilation in horses with severe asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Airway dysfunction in severe equine asthma (SEA) often results in early retirement or euthanasia of affected horses. Exercise‐induced bronchodilation occurs in horses with SEA after intense treadmill exercise, but the effects of a lighter, field‐applicable, training regimen remain largely unexplored.
Sophie Mainguy‐Seers, Sarah‐Maude Grondin, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Adding anticholinergics in acute childhood and adolescent asthma is cost effective

, 1999

openalex   +2 more sources

Antioxidant, Antiglaucoma, Anticholinergic, and Antidiabetic Effects of Kiwifruit (Actinidia deliciosa) Oil: Metabolite Profile Analysis Using LC-HR/MS, GC/MS and GC-FID [PDF]

, 2023
Eda Mehtap Özden, Zeynebe Bingöl, Muzaffer Mutlu, Hasan Karageçili, Ekrem Köksal, Ahmet C. Gören, Saleh Alwasel, İlhami Gülçın   +7 more
openalex   +1 more source

Parkinson's Disease and Salivary Issues: A Survey

Gerodontology, EarlyView.
ABSTRACT Background Salivary dysfunction, including xerostomia and drooling, is common in Parkinson's disease and further impairs oral health and quality of life, which are already compromised in this population. Their effective management demands deeper insight into the complexity of salivary dysfunction.
Beau D. M. van Dijk, Merel C. Verhoeff, Niels van der Aa, Frank Lobbezoo   +3 more
wiley   +1 more source

Case Report: Atropine-induced delirium in a dog

Frontiers in Veterinary Science
A 6-year-old spayed female Goldendoodle was presented as a referral for bradycardia and collapse. An electrocardiogram revealed a high-grade second-degree atrioventricular block (HG2AVB) with atrial flutter.
Samantha Fedotova, Heidi B. Kellihan, Lesley Smith, Kyle Bartholomew   +3 more
doaj   +1 more source