Results 231 to 240 of about 745,415 (340)

Continuous Evaluation Frameworks for Retrospective Evaluation of Clinical Machine Learning Models. [PDF]

Crit Care
Natarajan A, Chang Y, McLaverty B, Adhikari L, Ghosh E.   +4 more
europepmc   +1 more source

Hope and anticipation in education for a sustainable future

, 2017
M. Ojala
semanticscholar   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The role of attention in the generation of anticipatory potentials to affective stimuli: an ERP and source analysis study. [PDF]

Cereb Cortex
Benzaquén E, Griffiths TD, Kumar S.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Acute Change of Footwear Limits Performance and Alters Foot Strike Patterns During Anticipated and Unanticipated 90° Change of Direction. [PDF]

J Foot Ankle Res
Siegel SD, Sproll M, Warneke K, Mason J, Zech A.   +4 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Anticipation of periodic events influences cell motility in amoeba proteus. [PDF]

Sci Rep
Mueller SM, Martin S, Morawski M, Stieler J, Holzer M, Grunwald M.   +5 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

EEG Monitoring of Temporal Anticipation in Coincidence Anticipation Timing Tasks: A Scoping Review With Recommendations. [PDF]

Brain Behav
Dos Santos AF, de Melo GC, Castellano G, Forner-Cordero A.   +3 more
europepmc   +1 more source