Results 81 to 90 of about 106,247 (265)

Enhancing Cognitive Function through Physical Education: The Impact of Physical Education Activity on Attention and Focus

Journal on Efficiency and Responsibility in Education and Science
Aim: This study investigates the impact of an enhanced physical education (PE) program on attentional functions in middle school students. The aim is to evaluate whether increasing physical education hours, with an emphasis on cognitive tasks and team ...
Matteo Giuriato, Nicola Lovecchio
doaj   +1 more source

Tele-Guidance System to Support Anticipation during Communication

Multimodal Technologies and Interaction, 2018
Tele-guidance systems for the remote monitoring and maintenance of equipment have been extensively investigated. Such systems enable a remote helper to provide guidance to a local worker while perceiving local conditions. In this study, we propose a tele-
Takuya Yamamoto, Mai Otsuki, Hideaki Kuzuoka, Yusuke Suzuki   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Virtual Reality as a Perceptual-Motor Training Tool: Validity and Fidelity Assessments of a 4 × 100 m Relay Simulator

Applied Sciences
The use of virtual reality simulators for perceptual-motor training has increased in recent years. However, few virtual sport environments have been shown to be effective in transferring learning to the real world.
Martin Egiziano, Loïc Chomienne, Valentin Hervet, Nicolas Mascret, Richard Kulpa, Gilles Montagne   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

An 8-week physical exercise intervention for e'athletes improves physical performance rather than short-term esports performance parameters - a randomized controlled trial

Frontiers in Sports and Active Living
IntroductionEsports have been suggested to enhance hand-eye coordination, fine motor skills, and reaction times. While physical exercise is known to improve these abilities, its impact on short-term esports performance is under-researched.
Felix Wachholz, Nicole Gamper, Martin Schnitzer   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source