Results 151 to 160 of about 264,953 (386)

Factors XI and XII as Targets for New Anticoagulants

open access: yesFrontiers in Medicine, 2017
Compared with vitamin K antagonists, the direct oral anticoagulants (DOACs) are simpler to administer and are associated with less intracranial bleeding.
J. Weitz, J. Fredenburgh
semanticscholar   +1 more source

Topics of Interest in Women With Myeloproliferative Neoplasms

open access: yesAmerican Journal of Hematology, EarlyView.
Women with MPN: life‐cycle phases, specific risks, and influencing factors. ABSTRACT Overview Sex and gender have emerged as central modifiers of disease biology, phenotype, and clinical outcomes in myeloproliferative neoplasms (MPNs). This review will uniquely highlight issues affecting women with MPN and articulate their relevant determinants ...
Natasha Szuber   +2 more
wiley   +1 more source

Second-Order Inference for the Mean of a Variable Missing at Random [PDF]

open access: yesarXiv, 2015
We present a second-order estimator of the mean of a variable subject to missingness, under the missing at random assumption. The estimator improves upon existing methods by using an approximate second-order expansion of the parameter functional, in addition to the first-order expansion employed by standard doubly robust methods. This results in weaker
arxiv  

Optimal Timing for Resumption of Anticoagulation After Intracranial Hemorrhage in Patients With Mechanical Heart Valves

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Anticoagulation in patients with intracranial hemorrhage (ICH) and mechanical heart valves is often held for risk of ICH expansion; however, there exists a competing risk of acute ischemic stroke (AIS). Optimal timing to resume anticoagulation
Megan E. Barra   +6 more
doaj   +1 more source

A Novel Two-stage Deming Regression Framework with Applications to Association Analysis between Clinical Risks [PDF]

open access: yesarXiv
In healthcare, clinical risks are crucial for treatment decisions, yet the analysis of their associations is often overlooked. This gap is particularly significant when balancing risks that are weighed against each other, as in the case of atrial fibrillation (AF) patients facing stroke and bleeding risks with anticoagulant medication.
arxiv  

Admissibility in Partial Conjunction Testing [PDF]

open access: yesarXiv, 2015
Meta-analysis combines results from multiple studies aiming to increase power in finding their common effect. It would typically reject the null hypothesis of no effect if any one of the studies shows strong significance. The partial conjunction null hypothesis is rejected only when at least $r$ of $n$ component hypotheses are non-null with $r = 1 ...
arxiv  

Acute upper and lower gastrointestinal bleeding management in older people taking or not taking anticoagulants: a literature review

open access: yesFrontiers in Medicine
Acute upper and lower gastrointestinal (GI) bleeding may be a potentially life-threatening event that requires prompt recognition and an early effective management, being responsible for a considerable number of hospital admissions. Methods. We perform a
Danilo Menichelli   +6 more
doaj   +1 more source

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