Results 151 to 160 of about 355,585 (385)

Inhibition of heparanase-mediated degradation of extracellular matrix heparan sulfate by non-anticoagulant heparin species [PDF]

, 1987
M Bar-Ner, Amiram Eldor, L Wasserman, Y Matzner, Cohen Ir, Zvi Fuks, I Vlodavsky   +6 more
openalex   +1 more source

Use of tramadol and the risk of bleeding complications in patients on oral anticoagulants: a systematic review and meta-analysis

, 2022
Clara Lévy, Laëtitia Gosselin, Ana‐Maria Vilcu, Olivier Steichen   +3 more
openalex   +2 more sources

Pharmacology of anticoagulants used in the treatment of venous thromboembolism

Journal of Thrombosis and Thrombolysis, 2016
Anticoagulant drugs are the foundation of therapy for patients with VTE. While effective therapeutic agents, anticoagulants can also result in hemorrhage and other side effects.
E. Nutescu, Allison E. Burnett, J. Fanikos, S. Spinler, A. Wittkowsky   +4 more
semanticscholar   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

Advanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu, Gaofeng Li, Wenyi Wan, Jinsheng Li, Ge Yan, Shijie Wang, Xiuqi Hu, Zongqi Han, Yazheng Shan, Ying Zhou, Nianguo Dong, Weihua Qiao   +11 more
wiley   +1 more source

Comparative Analysis of Antithrombotic Therapy Outcomes in Mild Traumatic Brain-Injury Patients: A Focus on Bleeding Risk and Hospital-Stay Duration

Life
Background: Traumatic brain injury (TBI) in the elderly is a noteworthy pathology due to the exponential increase in population age, and the effects of antiplatelet and anticoagulation on patients’ outcomes are still a matter of dispute.
Antonio Desai, Dana Shiffer, Mauro Giordano, Alice Giotta Lucifero, Elena Generali, Francesco Reggiani, Marta Calatroni, Gabriele Savioli, Sabino Luzzi, Antonio Voza   +9 more
doaj   +1 more source

Patient-Reported Satisfaction and Study Drug Discontinuation: Post-Hoc Analysis of Findings from ROCKET AF. [PDF]

, 2019
IntroductionPatient-reported outcomes (PROs) and satisfaction endpoints are increasingly important in clinical trials and may be associated with treatment adherence.
Becker, Richard C, Berkowitz, Scott D, Breithardt, Guenter, Fox, Keith AA, Hacke, Werner, Halperin, Jonathan L, Hankey, Graeme J, Hellkamp, Anne S, Mahaffey, Kenneth W, Nessel, Christopher C, Patel, Manesh R, Piccini, Jonathan P, Rodriguez, Fatima, Singer, Daniel E, Ungar, Leo   +14 more
core   +1 more source

In-hospital Bleeding Outcomes of Oral Anticoagulant and Dual Antiplatelet Therapy During Percutaneous Coronary Intervention: An Analysis From the Japanese Nationwide Registry

, 2021
Fumiaki Yashima, Taku Inohara, Hiroaki Nishida, Kenichiro Shimoji, Koji Ueno, Shigetaka Noma, Kyohei Yamaji, Hideki Ishii, Nobuhiro Tanaka, Shun Kohsaka, Tetsuya Amano, Yuji Ikari   +11 more
openalex   +1 more source

Vitamin K antagonists: relative strengths and weaknesses vs. direct oral anticoagulants for stroke prevention in patients with atrial fibrillation

Journal of Thrombosis and Thrombolysis, 2016
Vitamin K antagonists (VKAs) have been the mainstay of anticoagulation therapy for more than 50 years. VKAs are mainly used for the prevention of stroke in patients with atrial fibrillation (AF) and the treatment and secondary prevention of venous ...
A. Zirlik, C. Bode
semanticscholar   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

The role of oral anticoagulants in epistaxis

European Archives of Oto-Rhino-Laryngology, 2018
PurposeThe purpose of this retrospective study was to identify the impact of oral anticoagulants on epistaxis with the focus on new oral anticoagulants.MethodsThe study was conducted at the Department  for Ear- Nose- and Throat (ENT), Head and Neck ...
A. Buchberger, A. Baumann, F. Johnson, N. Peters, Guido Piontek, K. Storck, A. Pickhard   +6 more
semanticscholar   +1 more source