Results 151 to 160 of about 261,124 (307)

The Biologically Enhanced Anterior Cruciate Ligament Reconstruction With Combined Injection of Harvested Platelet‐Rich Plasma, Thrombin, and Bone Marrow Aspirate Concentrate

open access: yesArthroscopy Techniques, EarlyView.
Abstract Despite continuous advances, anterior cruciate ligament reconstruction still struggles to restore full native knee function, as most techniques improve mechanical stability but overlook biological healing. The described superenhanced anterior cruciate ligament reconstruction technique aims to address this biological problem through a quadruple
Akram Aldawoudy   +3 more
wiley   +1 more source

Risk of venous thromboembolism after SARS‐CoV‐2 vaccination—Evidence from genome‐wide association study and population‐based observational study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim We aimed to investigate whether genetic variation is associated with venous thromboembolism after immunization with SARS‐CoV‐2 vaccines. Methods We conducted a genome‐wide association study (GWAS) on cases of venous thromboembolism within 42 days after SARS‐CoV‐2 vaccination, recruited from reports of adverse drug reactions sent to the Swedish ...
Sofia Attelind   +7 more
wiley   +1 more source

Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen   +14 more
wiley   +1 more source

Comparative effectiveness of parenteral anticoagulants (fondaparinux, argatroban, bivalirudin) in heparin-induced thrombocytopenia: A systematic review. [PDF]

open access: yesWorld J Methodol
Rehman A   +11 more
europepmc   +1 more source

Applying machine learning to pharmacovigilance data: A proof‐of‐concept study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Machine learning (ML) applications in pharmacovigilance remain limited and underexplored. Using data from the French National pharmacovigilance database (FNPV), this proof‐of‐concept study aimed to assess the feasibility of using a ML algorithm—eXtreme Gradient Boosting (XGBoost)—combined with SHapley Additive exPlanations (SHAP) analysis, to ...
Romain Barus   +6 more
wiley   +1 more source

Antithrombotic treatment with direct‐acting oral anticoagulants in patients with splanchnic vein thrombosis and cirrhosis

open access: yesLiver international (Print), 2017
A. de Gottardi   +23 more
semanticscholar   +1 more source

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