Results 231 to 240 of about 48,636 (289)

Kidney status and events preceding death in heart failure: A real‐world nationwide study

open access: yesEuropean Journal of Heart Failure, EarlyView.
Abstract Aims Chronic kidney disease is a frequent comorbidity in heart failure (HF) patients, affecting prognosis and mortality. This study investigates the relationship between kidney function and adverse kidney events preceding death in HF patients. Methods and results We analysed registry data of HF patients who died between 2014 and 2021, with at ...
Deewa Zahir Anjum   +9 more
wiley   +1 more source

How to handle polypharmacy in heart failure. A clinical consensus statement of the Heart Failure Association of the ESC

open access: yesEuropean Journal of Heart Failure, EarlyView.
Linking guideline‐directed medical therapy (GDMT) implementation and appropriate polypharmacy management in heart failure (HF). Polypharmacy can represent a barrier to the proper implementation of life‐prolonging GDMT for HF. A reasonable balance between the optimization of GDMT and avoiding inappropriate polypharmacy is mandatory in the contemporary ...
Davide Stolfo   +27 more
wiley   +1 more source

The role of ubiquitin C–terminal hydrolase (UCH‐L1) and protein S100B in differentiating patients with epileptic and psychogenic non‐epileptic seizures – Pilot study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Psychogenic non‐epileptic seizures (PNES) are functional neurological disorders that are often misdiagnosed and treated as epileptic seizures (ES). Video‐electroencephalography (v‐EEG) is the gold standard for differentiating ES from PNES.
Biljana Dapic Ivancic   +5 more
wiley   +1 more source

Corrigendum: Direct oral anticoagulants for the treatment of cerebral venous thrombosis – a protocol of an international phase IV study

open access: yesFrontiers in Neurology
Anita van de Munckhof   +32 more
doaj   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

open access: yesExploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

Riding a Vascular Time Train to Spatiotemporally Attenuate Thrombosis and Restenosis by Double Presentation of Therapeutic Gas and Biomacromolecules

open access: yesExploration, EarlyView.
This project develops a biomimetic stent coating with a double presentation of therapeutic biomacromolecule VEGF and therapeutic gas NO, which spatiotemporally promotes vessel repair including promoting rapid re‐endothelialization, effectively preventing thrombosis, suppressing inflammation and restenosis.
Jingdong Rao   +10 more
wiley   +1 more source

Impact of Heavy Slow Resistance vs. Convectional Exercise in Lateral Epicondylitis—A Pilot Study

open access: yesHealth Care Science, EarlyView.
ABSTRACT Background The extensor carpi radial muscle may become imbalanced compared to other muscles in the upper arm and can disrupt the overall muscle balance in the upper limb. This muscular imbalance may then cause inflammation or irritation in the tendon. Regular physical activity is rarely used as the only treatment for lowering limb edema. Heavy
S. M. Divya Mary   +3 more
wiley   +1 more source

Prognostic Factors for Free Flap Failure in Head and Neck Reconstruction

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The failure rate of free flaps varies from 0.8% to 10.6% in the literature in head and neck reconstruction. The primary objective was to identify prognostic factors for free flap failure. Methods We prospectively included all consecutive free flaps performed between August 2021 and January 2024, and used a multivariate Cox ...
Quentin Hennocq   +10 more
wiley   +1 more source

New anticoagulants

Current Opinion in Hematology, 2006
Abstract Traditional anticoagulant drugs, including unfractionated heparin and warfarin, have several limitations. New anticoagulants have been developed that target a single coagulation factor and have predictable dose-response relationships. These include direct thrombin inhibitors and factor Xa inhibitors.
AGNELLI, Giancarlo, BECATTINI, Cecilia
openaire   +6 more sources

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