Results 241 to 250 of about 355,585 (385)

Design, Synthesis, and Molecular Docking of Triazole‐Coumarin Hybrids as Potent Breast Cancer Inhibitors Targeting Cell Cycle and Apoptosis

Chemistry &Biodiversity, EarlyView.
Triazole‐coumarin hybrids were synthesized as breast cancer inhibitors. Derivative 5f induced S‐phase arrest and apoptosis in cancer cells, with minimal toxicity to healthy cells, showing promise for anticancer drug development. ABSTRACT Breast cancer continues to pose a significant global health burden, highlighting the urgent need for novel ...
Murat Keser, Emre Menteşe, Suleyman Ilhan, Mustafa Emirik, Harika Atmaca   +4 more
wiley   +1 more source

Oral anticoagulation for adults with atrial fibrillation or venous thromboembolism. [PDF]

Aust Prescr
Chin PK, Doogue MP.
europepmc   +1 more source

Anticoagulant treatment for subsegmental pulmonary embolism [PDF]

, 2020
Hugo Hyung Bok Yoo, Vania Santos Nunes-Nogueira, Paulo José Fortes Villas Bôas   +2 more
openalex   +1 more source

Trends in the prescription of novel oral anticoagulants in UK primary care

British Journal of Clinical Pharmacology, 2017
Simone Y Loo, S. Dell'aniello, L. Huiart, C. Renoux   +3 more
semanticscholar   +1 more source

Human Protein Z as the Second Known Heme‐Binding Protein from the Endogenous Blood Coagulation Inhibitor System

ChemBioChem, EarlyView.
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley   +1 more source

Pre-arrest oral anticoagulants' impact on cardiac arrest mortality: MIMIC-IV cohort retrospect. [PDF]

Front Cardiovasc Med
Nie X, He L, Zheng X.
europepmc   +1 more source

Use of the direct oral anticoagulants in obese patients: guidance from the SSC of the ISTH

Journal of Thrombosis and Haemostasis, 2016
K. Martin, J. Beyer-Westendorf, B. Davidson, M. Huisman, P. Sandset, S. Moll   +5 more
semanticscholar   +1 more source

Endomyocardial Fibrosis Associated With Hypereosinophilic Syndrome: Diagnostic and Management Insights From a Case Report

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Endomyocardial fibrosis (EMF) is a rare form of restrictive cardiomyopathy associated with eosinophilic disorders, characterized by apical subendocardial fibrosis and thrombus formation. Cardiac magnetic resonance (CMR) provides a comprehensive, noninvasive evaluation, enabling diagnosis, assessment of disease activity, and guidance of therapy.
Ibrahim Antoun, Benjamin Marrow, Ravi Pathmanathan, Sanjay S. Bhandari   +3 more
wiley   +1 more source

Chronic anticoagulation therapy associated with increased complications following hemiarthroplasty in hip fracture patients. [PDF]

Eur J Orthop Surg Traumatol
Shabani S, Wier J, Mulakaluri A, McCavitt D, Duong A, Firoozabadi R, Patterson J.   +6 more
europepmc   +1 more source

Anticoagulant therapy and altered tissue factor expression protect against experimental placental and cerebral malaria

Alicer K. Andrew, Tara C Bracken, Nicole M Nazario-Maldonado, Brittany N. Russ, Kathyrn T Gonzalvo, Benjamin M. Brainard, Nigel Mackman, Julie M. Moore   +7 more
openalex   +1 more source