Results 261 to 270 of about 355,585 (385)

Updated European Heart Rhythm Association practical guide on the use of non-vitamin-K antagonist anticoagulants in patients with non-valvular atrial fibrillation: Executive summary

European Heart Journal, 2016
H. Heidbuchel, P. Verhamme, M. Alings, M. Antz, H. Diener, W. Hacke, J. Oldgren, P. Sinnaeve, A. Camm, P. Kirchhof, Azhar Ahmad, J. Heinrich-Nols, S. Hess, M. Müller, Felix Münzel, M. Schwertfeger, Martin van Eickels, I. Richard-Lordereau, G. Lip, C. Chiang, J. Piccini, T. Potpara, L. Fauchier, D. Lane, Á. Avezum, T. Bjerregaard Larsen, G. Boriani, V. Roldán-Schilling, B. Gorenek   +28 more
semanticscholar   +1 more source

Comparative Bioequivalence and Safety Evaluation of Ibuprofen/Phenylephrine Hydrochloride Fixed‐Dose Combination Tablets in Healthy Chinese Volunteers

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This single‐center, randomized, open‐label bioequivalence program compared two fixed‐dose combination (FDC) tablets containing ibuprofen (200 mg) and phenylephrine hydrochloride (10 mg) from different manufacturers in healthy Chinese adults under fasting and fed conditions. A three‐period, partially replicated crossover design was used for the
Menghan Ye, Rui Zhang, Jing Wan, Jinping Zhou, Pengpeng Guo, Dianwen Yu, Peixia Li, Yani Liu, Shaojun Shi   +8 more
wiley   +1 more source

Pharmacovigilance Signal Detection of Drug-Induced Hospitalizations and Mortality: A 5-Year Nationwide Study. [PDF]

Healthcare (Basel)
Min J, Lee JE, Cho E, Im J, Choi YJ.
europepmc   +1 more source

Anticoagulant effects of Pseudechis australis (Australian king brown snake) venom on human blood: A computerized thromboelastography study

, 1995
Yoswa M. Dambisya, Tat‐Leang Lee, P. Gopalakrishnakone   +2 more
openalex   +2 more sources

Results of the ACCOuNT Trial: A Multi‐Institutional Prospective Pharmacogenomics Implementation Trial for African American Inpatients

Clinical Pharmacology &Therapeutics, EarlyView.
Pharmacogenomics implementation efforts have increased over the last decade, but no published prospective pharmacogenomics trials have formally evaluated utility in underrepresented populations. We present final results from the ACCOuNT trial, a multi‐institutional prospective study [NCT03225820] in which African American inpatients were genotyped and ...
Zhong Huang, Kevin J. O'Leary, Edith A. Nutescu, Matthew Jack, Thomas Chen, Gregory W. Ruhnke, James C. Lee, David George, Larry K. House, Randall Knoebel, Luke V. Rasmussen, Seth Hartman, Anish Choksi, Kiang‐Teck J. Yeo, Minoli A. Perera, Mark J. Ratain, David O. Meltzer, Peter H. O'Donnell   +17 more
wiley   +1 more source

Anticoagulant Usage and Risk of Thromboembolic Events After Ischemic Stroke in Adults With Cancer. [PDF]

Neurology
Balali P, Acton EK, Elser H, Navi BB, Kasner SE.   +4 more
europepmc   +1 more source

Quantitative Model‐Informed Dose Selection for a Milvexian Phase III Study in Patients With Atrial Fibrillation

Clinical Pharmacology &Therapeutics, EarlyView.
Milvexian, an activated factor XI inhibitor, is being evaluated in the LIBREXIA phase III program for the prevention of thrombotic events, including in patients with atrial fibrillation (LIBREXIA AF). To guide the selection of a phase III dose regimen for LIBREXIA AF, two main approaches were used: (1) population pharmacokinetics and exposure–response ...
Wangda Zhou, Emily Bozenhardt, Gregory E. Alexander, Matthew L. Zierhut, Samira Merali, Antoinette Ajavon‐Hartmann, Peter Zannikos, Hyunmoon Back, EunYoung Suh, Navin Goyal, Mahesh N. Samtani, Alexei N. Plotnikov, Chandni Valiathan   +12 more
wiley   +1 more source

Risk of Hemorrhagic Complications and Secondary Surgery in Patients on Warfarin vs DOACs Undergoing Glaucoma Surgery. [PDF]

Clin Ophthalmol
Ehsan H, Abdullah Z, Syed MF.
europepmc   +1 more source

Intracerebral hematomas during anticoagulant treatment. [PDF]

, 1990
C L Franke, Jeroen de Jonge, John C. van Swieten, A A Op de Coul, J. van Gijn   +4 more
openalex   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs and Risk of Gastrointestinal Bleeding: A Systematic Review and Meta‐Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used for pain and inflammation but are associated with gastrointestinal (GI) bleeding. While this risk is well established, most studies evaluate NSAIDs as a homogenous class, limiting clinical decision‐making based on individual agent safety.
Abdelrahman G. Tawfik, Ainhoa Gomez‐Lumbreras, Guilherme Del Fiol, Kensaku Kawamoto, Katy E. Trinkley, Thomas Reese, Aubrey Jones, Daniel C. Malone   +7 more
wiley   +1 more source