Results 291 to 300 of about 227,135 (339)

No relevant pharmacokinetic interaction between the KRAS G12C inhibitor sotorasib and the direct oral anticoagulant rivaroxaban in healthy subjects

International Journal of Cancer, EarlyView.
What's New? Venous thromboembolism (VTE) is common in cancer patients, with direct oral anticoagulants, including rivaroxaban, recommended as first‐line therapy. However, oral anticoagulant use is limited due to the growing use of targeted therapy and concerns about drug‐drug interactions.
Esther M. Hollander, Alessandra I. G. Buma, Jenneke Leentjens, Paddy K. C. Janssen, Michel M. van den Heuvel, David M. Burger, Berber Piet, Rob ter Heine   +7 more
wiley   +1 more source

Hemorrhage Risk Associated with Anticoagulant and Antiplatelet Drug Combinations: Insights from the USFDA Adverse Event Reporting System. [PDF]

J Clin Med
Sridharan K, Sivaramakrishnan G.
europepmc   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka   +11 more
wiley   +1 more source

Evaluation of Factors Associated with Intracranial Hemorrhage in Patients Presenting to the Emergency Department with Head Trauma: A Prospective Observational Study. [PDF]

J Clin Med
Parpucu Bagceci K, Gok PG, Baloglu Kaya F, Acar N, Ozakin E, Karakilic E, Canakci ME.   +6 more
europepmc   +1 more source

Uncovering the role of genetic polymorphisms in cervical insufficiency

International Journal of Gynecology &Obstetrics, EarlyView.
Pathways and genes implicated in CI pathogenesis. Abstract Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid‐trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks.
Kallirhoe Kalinderi, Michail Kalinderis, Maria Chatzidimitriou, Liana Fidani   +3 more
wiley   +1 more source

Decision-making regarding anticoagulant therapy in the last phase of life: In-depth interview study with healthcare professionals (the OPTIMA trial). [PDF]

Palliat Med
van Hylckama Vlieg MAM, de Beukelaar KJI, Spreeuw RHL, Kruip MJHA, Kuy PHMV, Heide AV, van der Rijt CCD, Geijteman ECT.   +7 more
europepmc   +1 more source

Hemostatic abnormalities at the time of fetal death: A retrospective study evaluating the prevalence and relevance of targeted testing

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess the prevalence of hemostasis abnormalities at the time of fetal death diagnosis. Methods This retrospective single‐center study included all fetal deaths between 22 and 42 weeks from July 2017 to December 2023, excluding multiple pregnancies, patients on anticoagulant therapy, and those with known pre‐existing coagulation ...
Chloé Lieng, Catherine Fischer, Aude Girault   +2 more
wiley   +1 more source

Pharmacovigilance Signal Detection of Drug-Induced Hospitalizations and Mortality: A 5-Year Nationwide Study. [PDF]

Healthcare (Basel)
Min J, Lee JE, Cho E, Im J, Choi YJ.
europepmc   +1 more source

Anticoagulant Usage and Risk of Thromboembolic Events After Ischemic Stroke in Adults With Cancer. [PDF]

Neurology
Balali P, Acton EK, Elser H, Navi BB, Kasner SE.   +4 more
europepmc   +1 more source