Results 141 to 150 of about 230,224 (366)

Impact of Age and Factor Xa Inhibitor Concentrations on Bleeding Risk in Patients with Atrial Fibrillation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
This study aimed to analyze differences in the exposure‐response relationship for factor Xa inhibitors (FXaI) between patients aged ≥ 80 and < 80 years. Patients with atrial fibrillation (AF) taking rivaroxaban, apixaban, or edoxaban were enrolled, and a single steady‐state trough concentration was measured.
Shin‐Yi Lin   +7 more
wiley   +1 more source

Anticoagulation Quality and Complications of using Vitamin K Antagonists in the Cardiac Surgery Outpatient Clinic

open access: yesBrazilian Journal of Cardiovascular Surgery
Introduction: In patients with mechanical prosthetic heart valves or atrial fibrillation requiring anticoagulation to prevent thromboembolic events, several factors influence adherence and anticoagulation complications.
Mário Augusto Cray da Costa   +5 more
doaj   +1 more source

Comparison of Heparin Red, Azure A and Toluidine Blue assays for direct quantification of heparins in human plasma [PDF]

open access: yesarXiv, 2017
Heparins are are sulfated polysaccharides that have tremendous clinical importance as anticoagulant drugs. Monitoring of heparin blood levels can improve patient safety. In clinical practice, heparins are monitored indirectly by their inhibtory effect on coagulation proteases.
arxiv  

Activated Clotting Times versus Protocol Anticoagulation Management [PDF]

open access: bronze, 1983
James P. Dearing   +3 more
openalex   +1 more source

Navigating Pharmacogenomic Testing in Practice: Who to Test and When to Test

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
There is increasing attention on the clinical utility and value of pharmacogenetic (PGx) testing to individualize medication management. Most clinical practice guidelines from medical professional societies do not recommend routine PGx testing, with a few key exceptions.
James M. Stevenson   +4 more
wiley   +1 more source

Progress in Pharmacogenomics Implementation in the United States: Barrier Erosion and Remaining Challenges

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Barriers to incorporating pharmacogenetics into routine clinical practice in the United States are well documented. Initial surveys by the Clinical Pharmacogenetics Implementation Consortium (CPIC) in 2009 and 2010 identified barriers across four key domains that have hindered the widespread adoption of clinical pharmacogenetic testing.
D. Max Smith   +18 more
wiley   +1 more source

Acute anticoagulation following cardioembolic stroke. [PDF]

open access: bronze, 1989
John F. Rothrock   +4 more
openalex   +1 more source

MELD score predicts outcomes in patients with advanced heart failure: A longitudinal evaluation

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 839-847, April 2025.
Abstract Aims Advanced heart failure (AHF) is characterized by recurrent episodes of haemodynamic instability and frequent hospitalizations, leading to a progressive decline in quality of life and high mortality rates. The objectives of this study were to evaluate the effect of the model for end‐stage liver disease (MELD) score and its variations in ...
Francesco Curcio   +10 more
wiley   +1 more source

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