Results 291 to 300 of about 234,465 (343)

Momelotinib Is Effective in Treatment for VEXAS Syndrome: Two Cases Within the AGMT Austrian Myeloid Registry

European Journal of Haematology, EarlyView.
ABSTRACT VEXAS syndrome is caused by somatic mutations in the UBA1 gene and includes features of both autoinflammatory and myeloid diseases. Among several treatment options, JAK inhibitors have proven effective, especially ruxolitinib. However, anemia is often present in VEXAS syndrome.
Dominik Kiem, Michael Leisch, Ildiko Toth, Marie‐Christina Mayer, Lisa Pleyer, Richard Greil, Alexander Egle, Thomas Melchardt   +7 more
wiley   +1 more source

Quality of vitamin K antagonist treatment during the last year of life. [PDF]

Hemasphere
Visser C, Kempers EK, Goedgebuur J, Abbel D, Aldridge SJ, Edwards A, Edwards M, Geersing GJ, Ording AG, van de Leur SJCM, Lifford KJ, Mahé I, Mooijaart SP, Nierman MC, Portielje JEA, Søgaard M, Szmit S, Wiersma NM, Noble SIR, Klok FA, Chen Q, Cannegieter SC, Geijteman ECT, Kruip MJHA, SERENITY Consortium.   +24 more
europepmc   +1 more source

Insulin facilitates entry of calcium ions into human and murine erythrocytes via Piezo1: a newly identified mechanism with implications for type 2 diabetes

The FEBS Journal, EarlyView.
Despite being enucleated, mammalian red blood cells (RBCs) possess complex signaling mechanisms. Here, we show that insulin signals through the mechanosensitive channel Piezo1 to promote influx of calcium ions. This newly identified pathway is disrupted in a murine model of type 2 diabetes and may contribute to driving circulatory deficits in prevalent
Lennart Kuck, Tia A. Griffith, Antony P. McNamee, Jason N. Peart, John H. Wilson, Ajay Sharma, Lavanya A. Sharma, Kai Robertson, Eugene F. Du Toit, Michael J. Simmonds   +9 more
wiley   +1 more source

Effect of endovascular management and anticoagulation alone on acute deep venous thrombosis in patients with inferior vena cava thrombosis. [PDF]

Sci Rep
Sun L, Yang T, Xu H, Zhang W.
europepmc   +1 more source

Aging China's cardiac challenge: Projected growth of atrial arrhythmia cases and healthcare preparedness through 2045 — A global burden disease analysis

Geriatrics &Gerontology International, EarlyView.
Atrial fibrillation/flutter cases in China have tripled since 1990. Using GBD 2021 data and BAPC modeling, this study projects rising incidence and prevalence through 2045, driven by aging and metabolic risk. Targeted, China‐specific prevention and digital health strategies are urgently needed to mitigate future burden.
Junpeng Xiong, Shuwen Chen, Xiaoli Wu, Bingyin Wang, Binquan You, Ronghui Yu   +5 more
wiley   +1 more source

Discrepancy between original and adapted ASH VTE guidelines: same clinical evidence but different recommendations. [PDF]

Blood Adv
Rezende SM, Neumann I, Djulbegovic B.
europepmc   +1 more source

Carbon Dioxide Digital Subtraction Angiography for Central Venous Recanalization in a Kidney Transplant Patient: A Case Report

Hemodialysis International, EarlyView.
ABSTRACT Background We present the case of a kidney transplant recipient with elevated serum creatinine who developed left upper limb swelling due to left subclavian vein thrombosis. Concerned about potential hemodialysis resumption, the patient prioritized preserving their arteriovenous fistula.
Limei Chen, Ruining Liu, Tianlei Cui
wiley   +1 more source

Impact of Anemia Management on Bleeding Outcomes in Anticoagulated Patients: A Retrospective Cohort Analysis. [PDF]

Clin Hematol Int
Godin SL, Hanna C, Naut E, Mulay S.
europepmc   +1 more source

Delayed Massive Hemothorax Induced by Tunneled Dialysis Catheter Placement via the Left Internal Jugular Vein: A Case Report

Hemodialysis International, EarlyView.
ABSTRACT The tunneled dialysis catheter is among the most commonly used vascular accesses for patients undergoing hemodialysis. Delayed hemothorax resulting from central venous perforation induced by catheterization is a rare but serious complication. However, there are few reports.
Ping Shi, Mengyue Zhu, Yi Zhang, Jun Xu, Hongbin Mou   +4 more
wiley   +1 more source