Results 71 to 80 of about 249,454 (294)
Objective Vacuoles E1 enzyme X‐linked autoinflammatory somatic syndrome (VEXAS) is a recently identified rare genetic disorder associated with somatic mutations in the UBA1 gene. VEXAS presents with a combination of inflammatory and hematologic manifestations, leading to increased morbidity and mortality.
Arsene Mekinian +111 more
wiley +1 more source
Objectives After elective cardiac surgery a postoperative anticoagulation is obligatory. With critically ill patients the conventional anticoagulation standard heparin is sometimes impossible, e.g. based on HIT II.
Matthias Klingele +5 more
doaj +1 more source
Portal vein thrombosis after laparoscopic splenectomy: an ongoing clinical challenge. [PDF]
ObjectivesPortal vein thrombosis (PVT) following open splenectomy is a potentially lethal complication with an incidence of up to 6%. The objective of this report is to describe our management of a recent laparoscopic case, discuss current therapies, and
Kee, Stephen T +4 more
core +2 more sources
Is porto sinusoidal vascular disease to be actively searched in patients with portal vein thrombosis? [PDF]
Porto sinusoidal vascular liver disease (PSVD) and portal vein thrombosis (PVT) are distinct vascular liver diseases characterized, respectively, by an intrahepatic and a prehepatic obstacle to the flow in the liver portal system. PVT may also occur as a
D'Amati, G. +4 more
core +1 more source
Safety of Needle Electromyography in Critically Ill Patients [PDF]
Introduction: To evaluate the safety of needle electromyography (EMG) in critically ill intensive care unit (ICU) patients who are on anticoagulants and have comorbidities that increase the risk of bleeding and infections.
Bollu, Pradeep +5 more
core +2 more sources
Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro +3 more
wiley +1 more source
Introduction: Systemic anticoagulation is widely used in routine clinical hemodialysis, but can be contraindicated in specific settings. Anticoagulant-free treatment regimens are prone to failure even in chronic intermittent hemodialysis.
Floris Vanommeslaeghe +5 more
doaj +1 more source
A real‐world data‐driven approach to optimizing enoxaparin dosing in burn patients
Aim Enoxaparin dosing in burn patients is challenging due to physiological changes affecting absorption, distribution and clearance. The objectives of this study are to develop a population pharmacokinetic (PK) model for enoxaparin in burn patients, evaluate target attainment with current equation‐based (EQ) dosing and propose an optimized dosing ...
Babajide Shenkoya +3 more
wiley +1 more source
A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysis
Protein-losing enteropathy (PLE) can be caused by erosive and nonerosive gastrointestinal diseases, mesenteric lymphatic obstruction, and increased central venous pressure. Superior mesenteric artery pathology (SMAP), including dissection or occlusion is
Nedaa Skeik, MD, FACC, FACP, FSVM, RPVI +3 more
doaj +1 more source
Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications [PDF]
This article reports the conclusions of the second part of a consensus expert conference on the nomenclature of renal replacement therapy (RRT) techniques currently utilized to manage acute kidney injury and other organ dysfunction syndromes in ...
Bagshaw, S. M. +66 more
core +4 more sources

