Results 71 to 80 of about 235,111 (295)

Abstract Number ‐ 238: More Rapid Anticoagulation is Safe for Cerebral Sinus Thrombosis Patients and Shortens ICU Stays

Stroke: Vascular and Interventional Neurology, 2023
Introduction Cerebral sinus thrombosis (CST) can often prove challenging to manage effectively. Anticoagulation is the accepted first‐line therapy for treatment, but heterogeneity exists among treatment protocols.
Anish Deshmukh, Gitanjali Das, Adam de Havenon, Vivek Reddy, Matthew D Alexander   +4 more
doaj   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

Venous thromboembolism in critically ill COVID-19 patients receiving prophylactic or therapeutic anticoagulation: a systematic review and meta-analysis

Journal of Thrombosis and Thrombolysis, 2020
Many aspects of care such as management of hypercoagulable state in COVID-19 patients, especially those admitted to intensive care units is challenging in the rapidly evolving pandemic of novel coronavirus disease 2019 (COVID-19).
S. Hasan, Sam Radford, C. S. Kow, S. T. R. Zaidi   +3 more
semanticscholar   +1 more source

Remote care instruction via the WeChat platform for female patients receiving subcutaneous anticoagulation during the COVID-19 pandemic: a retrospective analysis [PDF]

PeerJ
Background The purpose of this study was to estimate the effect of remote nursing guidance based on WeChat platform for female patients receiving subcutaneous anticoagulation during the COVID-19 epidemic.
Chao Yun Jiang, Ci Juan Li, Rong Zhang, Tian Hong Cai, Teng Hui Zhan   +4 more
doaj   +2 more sources

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

Advanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu, George Pitoc, Manqi Zhang, Jeffrey Clancy, James Frederiksen, Amy Yan, Samuel Francis, Rebecca Sullenger, Rachel Rempel, Susannah Gammell, Jillian Caiazzi, Bruce A. Sullenger   +11 more
wiley   +1 more source

3D Membrane Microstructures for Increased Efficiency in Blood‐Gas Transfer

Advanced Science, EarlyView.
Oxygenators for extracorporeal membrane oxygenation are based on hollow fiber membranes. They are associated with many complications, such as thrombosis or systemic inflammation during the therapy. By implementing 3D membrane microstructures for oxygenators, the transfer efficiency of oxygen and carbon dioxide is improved, which can lead to ...
Kai P. Barbian, F. Neuhaus, L. T. Hirschwald, J. Linkhorst, M. Wessling, B. Wiegmann, J. M. Focke, U. Steinseifer, M. Neidlin, S. V. Jansen   +9 more
wiley   +1 more source

The effect of postoperative anticoagulation on acute aortic dissection: a systematic review and meta-analysis

Frontiers in Cardiovascular Medicine, 2023
Background and aimThe evolution of the false lumen after the repair of acute aortic dissection has been linked to numerous adverse clinical outcomes, including increased late mortality and a higher risk of reoperation.
Xiangfeng Gong, Qianlei Lang, Chaoyi Qin, Chaoyi Qin, Wei Meng, Wei Meng, Zhenghua Xiao, Zhenghua Xiao   +7 more
doaj   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

Advanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu, Gaofeng Li, Wenyi Wan, Jinsheng Li, Ge Yan, Shijie Wang, Xiuqi Hu, Zongqi Han, Yazheng Shan, Ying Zhou, Nianguo Dong, Weihua Qiao   +11 more
wiley   +1 more source

Transcatheter embolization of anticoagulation related pancreatic pseudocyst hemorrhage: A case report

Radiology Case Reports, 2019
Hemorrhage associated with anticoagulation therapy is a feared and relatively common complication. Few cases have been documented of spontaneous pancreatic hemorrhage related to anticoagulation, and fewer yet of ruptured pancreatic pseudocyst secondary ...
Naomi K. Atkins, DO, Blake M. Kramer, DO, Charles A. Kitley, MD   +2 more
doaj   +1 more source

Deep Learning Model for Predicting Operative Mortality After Total Gastrectomy: Analysis of the Japanese National Clinical Database (NCD)

Annals of Gastroenterological Surgery, EarlyView.
Deep learning‐based prediction model for operative mortality using the National Clinical Database (NCD). The model achieved a C‐statistic of 0.74. ABSTRACT Background Radical gastrectomy with lymph node dissection is the primary treatment for gastric cancer.
Ryosuke Fukuyo, Hiroyuki Yamamoto, Masanori Tokunaga, Yusuke Kinugasa, Yoshihiro Kakeji, Ken Shirabe   +5 more
wiley   +1 more source