Results 81 to 90 of about 235,111 (295)

Facts and Misfacts on D‐Dimer Testing. Consensus Guidance From the Italian Society on Thrombosis and Hemostasis (SISET)

American Journal of Hematology, EarlyView.
ABSTRACT D‐dimer defines degradation products derived from the proteolysis mediated by plasmin on cross‐linked fibrin. The evidence‐based use of D‐dimer in some conditions has been consolidated. Currently, however, there is an entrenched prescription of D‐dimer testing to screen otherwise healthy subjects that may induce prescribing physicians to start
Armando Tripodi, Walter Ageno, Luca Barcella, Antonio Coppola, Marcello Di Nisio, Massimo Franchini, Monia Marchetti, Rossella Marcucci, Marco Marietta, Pasquale Pignatelli, Domenico Prisco, Valerio De Stefano   +11 more
wiley   +1 more source

Optimizing Asparaginase Treatment for Adolescent and Young Adult (AYA) Patients With Acute Lymphoblastic Leukemia: US Consensus Panel Recommendations

American Journal of Hematology, EarlyView.
ABSTRACT Asparaginase is an integral component of therapy for pediatric patients with acute lymphoblastic leukemia/lymphoblastic lymphoma. The success of asparaginase‐containing regimens has led to trials of pediatric/pediatric‐inspired regimens incorporating asparaginase for treating adolescent and young adult (AYA) and adult populations with acute ...
Ibrahim Aldoss, Amir Ali, Ryan D. Cassaday, Emily K. Curran, Marlise R. Luskin, Luke D. Maese, Etan Orgel, Dan Douer   +7 more
wiley   +1 more source

Anticoagulation in COVID-19

European Heart Journal - Cardiovascular Pharmacotherapy, 2020
As hospitals worldwide continue to admit an influx of coronavirus disease 2019 (COVID-19) patients, the puzzling pathogenesis behind the witnessed mortality rates is progressively being pieced together. Aside from the established respiratory involvement,
B. Atallah, Saad I. Mallah, W. Almahmeed
semanticscholar   +1 more source

Bleeding complications after cardiac surgery, before anticoagulation start and then with argatroban or heparin in the early postoperative setting

Journal of Cardiothoracic Surgery, 2020
Objectives After elective cardiac surgery a postoperative anticoagulation is obligatory. With critically ill patients the conventional anticoagulation standard heparin is sometimes impossible, e.g. based on HIT II.
Matthias Klingele, Julia Enkel, Timo Speer, Hagen Bomberg, Lea Baerens, Hans-Joachim Schäfers   +5 more
doaj   +1 more source

Protein S Enhances the Phagocytosis of Phosphatidylserine‐Exposing Erythrocytes: Implications in Sickle Cell Disease

American Journal of Hematology, EarlyView.
ABSTRACT The major anticoagulant Protein S (PROS1) also contributes to the phagocytosis of apoptotic cells by bridging exposed phosphatidylserine (PtdSer) to the MerTK receptor on macrophages (efferocytosis). Whether PROS1 is involved in the splenic clearance of PtdSer‐positive senescent and altered erythrocytes such as erythrocyte ghosts (eryghosts ...
Claire Auditeau, Aurélie Fricot, Raphaël Gauthier, Abdoulaye Sissoko, Zeynep Cacan, Céline Gounou, Laure Joseph, Sandra Manceau, Slimane Allali, Michael Dussiot, Mickael Marin, Alexis Lavergne, Mariem Khamari, Sophie Moog, Elsa Bianchini, Laetitia Claer, Sandrine Laurance, Valentine Brousse, Sébastien Eymieux, Philippe Roingeard, Pascal Amireault, Thiago Trovati Maciel, Alain Brisson, Pierre Buffet, François Saller, Delphine Borgel, Camille Roussel   +26 more
wiley   +1 more source

Evaluation of Different Dialyzers and the Impact of Predialysis Albumin Priming in Intermittent Hemodialysis With Reduced Anticoagulation

Kidney International Reports, 2019
Introduction: Systemic anticoagulation is widely used in routine clinical hemodialysis, but can be contraindicated in specific settings. Anticoagulant-free treatment regimens are prone to failure even in chronic intermittent hemodialysis.
Floris Vanommeslaeghe, Filip De Somer, Iván Josipovic, Matthieu Boone, Wim Van Biesen, Sunny Eloot   +5 more
doaj   +1 more source

A Multicenter Prospective Cohort Study on the Use of Weight‐Adjusted Dalteparin in Patients Over 90 kg With Acute Cancer‐Associated Venous Thromboembolism—The WAVe Study

American Journal of Hematology, EarlyView.
The WAVe stdudy‐ A multicenter prospective cohort study of wieght‐adjusted dalteparin in patients over 90 kg with acute cancer‐associated venous thromboembolism. ABSTRACT Patients with cancer‐associated thrombosis (CAT) are commonly treated with low‐molecular‐weight heparin (LMWH), but whether dose capping is needed in patients over 90 kg is unclear ...
Tzu‐Fei Wang, Erik Yeo, Peter L. Gross, Chantal Séguin, Cynthia Wu, Sudeep Shivakumar, Ranjeeta Mallick, Aurélien Delluc, Julien D'Astous, Miriam Kimpton, Guillaume Roberge, Deborah M. Siegal, Tobias Tritschler, Grégoire Le Gal, Marc Carrier   +14 more
wiley   +1 more source

A unique case of protein-losing enteropathy as a complication of segmental arterial mediolysis

Journal of Vascular Surgery Cases and Innovative Techniques
Protein-losing enteropathy (PLE) can be caused by erosive and nonerosive gastrointestinal diseases, mesenteric lymphatic obstruction, and increased central venous pressure. Superior mesenteric artery pathology (SMAP), including dissection or occlusion is
Nedaa Skeik, MD, FACC, FACP, FSVM, RPVI, Rebecca Windschitl, MD, Naureen Qadri, MD, Jesse Manunga, MD   +3 more
doaj   +1 more source

MEW/PVA‐MA Hydrogel Vascular Grafts: Enhancing Hemocompatibility and Endothelialization

Advanced NanoBiomed Research, EarlyView.
A biomimetic vascular graft combining biofunctionalized PVA‐MA hydrogels with a MEW scaffold is developed for small‐diameter applications. Gel‐MA and Hep‐MA incorporation enhances endothelialization and hemocompatibility, respectively, targeting the acute biological responses.
Verena Kronberger, Shouyuan Jiang, Minh H. Ho, Jasneil Singh, Chung‐Wei (Roy) Hsu, Gabriella C. J. Lindberg, Khoon S. Lim, Tomasz Jungst, Anna Waterhouse   +8 more
wiley   +1 more source

The Role of Anticoagulation in COVID-19-Induced Hypercoagulability

Current Cardiology Reports, 2020
Purpose of Review We aim to provide a comprehensive analysis of hypercoagulability in individuals affected by COVID-19. Our goal is to describe the hypercoagulable state related to the infection and provide guidance regarding the possible benefits of ...
J. S. Rico-Mesa, D. Rosas, Ashkan Ahmadian-Tehrani, A. White, A. Anderson, R. Chilton   +5 more
semanticscholar   +1 more source