Results 41 to 50 of about 46,422 (312)

A companion to the preclinical common data elements for phenotyping seizures and epilepsy in rodent models. A report of the TASK3‐WG1C: Phenotyping working group of the ILAE/AES joint translational task force

Epilepsia Open, EarlyView., 2022
Abstract Epilepsy is a heterogeneous disorder characterized by spontaneous seizures and behavioral comorbidities. The underlying mechanisms of seizures and epilepsy across various syndromes lead to diverse clinical presentation and features. Similarly, animal models of epilepsy arise from numerous dissimilar inciting events.
Melissa Barker‐Haliski, Julika Pitsch, Aristea S. Galanopoulou, Rüdiger Köhling   +3 more
wiley   +1 more source

Isovaleramida, principio anticonvulsivo aislado de Valeriana pavonii

Biomédica: revista del Instituto Nacional de Salud, 2010
Introducción. El fraccionamiento fitoquímico de Valeriana pavonii, especie vegetal nativa utilizada tradicionalmente en Colombia con fines tranquilizantes, condujo al aislamiento e identificación de la isovaleramida, uno de los principios responsables de
Sara Emilia Giraldo, Javier Rincón, Pilar Puebla, Mariel Marder, Cristina Wasowski, Nadezdha Vergel, Mario Francisco Guerrero   +6 more
doaj   +1 more source

Transient lesion in the splenium of the corpus callosum and a sudden antiepileptic drugs withdrawal: A case with focal epilepsy in presurgical evaluation [PDF]

Vojnosanitetski Pregled, 2010
Introduction. A sudden withdrawal of antiepileptic drugs gives higher rate of epileptic seizures in the settings of video electroencephalography (vEEG), monitoring that is a subject to further registration and analysis.
Ristić Aleksandar, Lavrnić Slobodan, Zović Ljubica, Vojvodić Nikola, Janković Slavko, Škrijelj Fadilj, Ercegovac Marko, Sokić Dragoslav   +7 more
doaj   +1 more source

Enaminone‐Based Push–Pull Chromophores: Synthesis, Optical Properties, and Computational Insights

Asian Journal of Organic Chemistry, EarlyView.
Enaminones, known for their pharmacophoric properties, were combined with alkyne units to create complex chromophore structures through click‐type [2 + 2] cycloaddition‐retroelectrocyclization reactions. The ICT characteristics of the synthesized compounds were analyzed using both experimental and computational approaches.
Mehmet Mart, Isıl Irmak Kuyucu, Cagatay Dengiz   +2 more
wiley   +1 more source

Epilepsy in the Elderly

International Journal of Gerontology, 2012
Elderly people are the largest and continuously fastest growing population among patients with epilepsy. Elderly patients with epilepsy are very different from other age groups in many respects and clinicians shouldn’t treat them in the same way as ...
Lu-An Chen, Shih-Jung Cheng, Shuo-Bin Jou   +2 more
doaj   +1 more source

Animal models of cisplatin‐induced neuropathic pain

Animal Models and Experimental Medicine, EarlyView.
This article illustrates the modeling process of a cisplatin‐induced neuropathic pain model in rats or mice. Multiple modeling tests are required for rats or mice before, during, and after modeling. The appropriate injection method, dose, and modeling method are selected, and multiple assays are chosen for evaluation and comparison.
Ningxin Li, Mingzhu Li, Shengbo Jin, Jun Yu, Hongzhe Wei, Wenping Wang, Siyao Ma, Yuxin Jiang, Qian Liu, Huini Yao   +9 more
wiley   +1 more source

Socioeconomic Outcome and Quality of Life in Adults after Status Epilepticus: A Multicenter, Longitudinal, Matched Case–Control Analysis from Germany

Frontiers in Neurology, 2017
BackgroundThere is a lack of data concerning socioeconomic outcome and quality of life (QoL) in patients after status epilepticus (SE) in Germany.Patients and methodsAdult patients treated between 2011 and 2015 due to SE at the university hospitals in ...
Lena-Marie Kortland, Susanne Knake, Felix von Podewils, Felix Rosenow, Felix Rosenow, Adam Strzelczyk, Adam Strzelczyk   +6 more
doaj   +1 more source

Tratamento cirúrgico de dor neuropática em membro inferior por ferimento de arma de fogo: relato de caso

Revista Dor
JUSTIFICATIVA E OBJETIVOS: O tratamento da dor neuropática é difícil e muitos pacientes apresentam alívio parcial e incompleto da dor com o tratamento farmacológico. Em casos de dor neuropática de origem traumática deve ser considerada a possibilidade de
Leonardo Eizo Watanabe, Mário Yoshihide Kuwae   +1 more
doaj   +1 more source

Pain management and stroke prevention in HHV-3-associated infection

Клиническая практика, 2019
The modern information on the epidemiology, pathogenesis, clinical manifestations, diagnosis and pain management in HHV-3-associated neuro-infection is presented. The criteria for the phased diagnostics and approaches to the rational therapy for shingles
O. V. Kolokolov, A. L. Bakulev, A. A. Shuldyakov, N. S. Makarov, I. V. Sitkali, A. M. Kolokolova, S. S. Kravchenya   +6 more
doaj   +1 more source

Visible Light‐Mediated Preparation of a Key Intermediate Employed in the Synthesis of Zolpidem and Several Analogs

Chemistry – An Asian Journal, EarlyView.
A new visible light‐induced method is reported for the C3‐alkylation of imidazo[1,2‐a]pyrimidines and ‐pyridines with aryldiazoacetates. This protocol can be performed in open air and serves as a convenient entry to several known and new molecules. A formal synthesis of zolpidem is achieved by changing the alkylating agent to an appropriate hypervalent
Ronei M. S. Souza, Tales A. C. Goulart, Roberto do C. Pinheiro, Felipe F. do C. Sonaglio, Deborah de A. Simoni, Rodrigo A. Cormanich, Igor D. Jurberg   +6 more
wiley   +1 more source