Results 161 to 170 of about 295,419 (335)

Evaluation of Antidepressant Activity of Plocama pendula root extract

, 2020
Dr.Kuppala Manohar Babu, Pandrinki Geetha Mounika, Rakurthi J S D Pawan kumar, Nunna Priyanka, Ayasetti Durga Sravani   +4 more
openalex   +2 more sources

Phenolic Profile and Bioactive Prospects of Wild Annona Species From Angola

Chemistry &Biodiversity, EarlyView.
ABSTRACT Annona species (Annonaceae family) are valued for their nutritional and medicinal importance, especially in traditional medicine. This study investigated the phenolic profiles of the Angolan Annona muricata, Annona squamosa, and Annona senegalensis leaves, stem barks, and seeds hydroethanolic, infusion, and decoction extracts, also evaluating ...
Josefa Rangel, Ângela Liberal, Tiane C. Finimundy, Tânia S. P. Pires, Pedro Cravo, Maria Conceição Silva, Gustavo Capatti Cassiano, Lillian Barros, Maria M. Romeiras, Ângela Fernandes   +9 more
wiley   +1 more source

Repeated Unpredictable Stress and Antidepressants Differentially Regulate Expression of the Bcl-2 Family of Apoptotic Genes in Rat Cortical, Hippocampal, and Limbic Brain Structures [PDF]

, 2007
Therese A. Kosten, Matthew P. Galloway, Ronald S. Duman, David Russell, Carrol D’Sa   +4 more
openalex   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

Peer Review #1 of "Impact of the antidepressant citalopram on the behaviour of two different life stages of brown trout (v0.1)"

, 2020
Michael G. Ziegler, Sarah Knoll, Heinz‐R. Köhler, Selina Tisler, Carolin Hühn, Christian Zwiener, Rita Triebskorn   +6 more
openalex   +1 more source

Drug‐Induced QT Prolongation: Associations Between Risk Classifications in a Swedish Clinical Decision Support System and Clinical Outcomes

Clinical Pharmacology &Therapeutics, EarlyView.
Potential adverse drug events can be signaled in Clinical Decision Support Systems (CDSSs). This study validated a Swedish CDSS (Janusmed Risk Profile) by investigating associations between calculated risk classifications of drugs with QT‐prolonging potential and registered related clinical outcomes.
Ola Nordqvist, Olof Björneld, Patrick Bergman, Björn Wettermark, Alisa Lincke, Marine L. Andersson, Tora Hammar   +6 more
wiley   +1 more source

Assessing the impact of pre‐test education on patient knowledge, perceptions, and expectations of pharmacogenomic testing to guide antidepressant use [PDF]

, 2022
Nicholette T. Sloat, Beverly M. Yashar, Vicki L. Ellingrod, Kristen M. Ward   +3 more
openalex   +1 more source

Paediatric developmental safety and the ICH E11A extrapolation of safety

British Journal of Clinical Pharmacology, EarlyView.
Gilbert J. Burckart, Susan M. Abdel‐Rahman, Gelareh Abulwerdi, Rebecca Racz, Sherbet Samuels, Dionna J. Green, Lynne P. Yao   +6 more
wiley   +1 more source

Applying Machine Learning to Predict Complex Clinical Course in Youth With Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To compare the predictive performance of supervised machine learning models to logistic regression in identifying youth with eating disorders at risk of a complex clinical course based on clinical characteristics from the first treatment episode.
Stephanie Ryall, Abigail Bradley, Khaled El Emam, Nicole Obeid   +3 more
wiley   +1 more source

Additional file 2 of Secondary care specialist visits made by children and young people prescribed antidepressants in primary care: a descriptive study using the QResearch database

, 2020
Ruth H Jack, Rebecca M. Joseph, Carol Coupland, Debbie Butler, Chris Hollis, Richard Morriss, Roger Knaggs, Andrea Cipriani, Samuele Cortese, Julia Hippisley‐Cox   +9 more
openalex   +1 more source