Results 161 to 170 of about 153,444 (192)
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New England Journal of Medicine, 1965
EIGHT years ago the introduction of iproniazid (Marsilid) and imipramine (Tofranil) opened a new era in the treatment of depression and a new area of psychiatric controversy. Many other antidepressants have since appeared, but, despite numerous investigations, opinions on the most appropriate therapy for depression continue to differ.
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EIGHT years ago the introduction of iproniazid (Marsilid) and imipramine (Tofranil) opened a new era in the treatment of depression and a new area of psychiatric controversy. Many other antidepressants have since appeared, but, despite numerous investigations, opinions on the most appropriate therapy for depression continue to differ.
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A Compendium of Antidepressants
Clinical Toxicology, 1979This compendium provides a quick reference to available tricyclic antidepressants, monoamine oxidase inhibitors, lithium carbonate, and stimulants. The charts include adult dosages, drug precautions, side effects, interactions with other drugs, and effects on clinical laboratory tests. Basic information on the prevention and management of overdose with
Nancy N. Cain, Russell M. Cain
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Annals of the New York Academy of Sciences, 1992
Abstract Suicidal thoughts and suicide attempts are an integral part of various depressions. Suicide attempts are common in major depression but even more common in recurrent brief depression, and the rate is further increased when these depressions occur comorbidly. Combined depression, where recurrent brief depression and major depression coexist, is
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Abstract Suicidal thoughts and suicide attempts are an integral part of various depressions. Suicide attempts are common in major depression but even more common in recurrent brief depression, and the rate is further increased when these depressions occur comorbidly. Combined depression, where recurrent brief depression and major depression coexist, is
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Accident Analysis & Prevention, 1985
Although some impairment of skills due to antidepressants has been observed clinically, the impact of antidepressants on traffic safety is at present unknown.
Markku Linnoila, Timo Seppälä
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Although some impairment of skills due to antidepressants has been observed clinically, the impact of antidepressants on traffic safety is at present unknown.
Markku Linnoila, Timo Seppälä
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Antidepressants and the Elderly
Journal of the American Geriatrics Society, 1986The pharmacologic treatment of depression in the elderly is often complicated by cardiovascular disease and other medical illnesses. Both the tricyclic antidepressants and the monoamine oxidase (MAO) inhibitors have adverse effects that are potentially dangerous in this age group.
Peabody, CA +2 more
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2006
Depression is defined as a mental disorder characterized by general emotional dejection and withdrawal, sadness greater and more prolonged than that warranted by an objective reason, extreme gloom, feelings of inadequacy, and an inability to concentrate.
Ruben Vardanyan, Victor J. Hruby
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Depression is defined as a mental disorder characterized by general emotional dejection and withdrawal, sadness greater and more prolonged than that warranted by an objective reason, extreme gloom, feelings of inadequacy, and an inability to concentrate.
Ruben Vardanyan, Victor J. Hruby
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CNS Drugs, 2008
Depression is a common accompaniment of pain, particularly when pain is unremitting. The use of a variety of antidepressant medications is associated with pain reduction, an effect that is independent of the mood-enhancing qualities of these drugs. This pain relief is a consequence of a wide variety of actions of antidepressants on the neuroregulatory ...
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Depression is a common accompaniment of pain, particularly when pain is unremitting. The use of a variety of antidepressant medications is associated with pain reduction, an effect that is independent of the mood-enhancing qualities of these drugs. This pain relief is a consequence of a wide variety of actions of antidepressants on the neuroregulatory ...
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Trends in Pharmacological Sciences, 2006
Tricyclic antidepressants, together with anticonvulsants, are considered to be first-line drugs for the treatment of neuropathic pain. Antidepressants are analgesic in patients with chronic pain and no concomitant depression, indicating that the analgesic and antidepressant effects occur independently.
Denis Ardid +3 more
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Tricyclic antidepressants, together with anticonvulsants, are considered to be first-line drugs for the treatment of neuropathic pain. Antidepressants are analgesic in patients with chronic pain and no concomitant depression, indicating that the analgesic and antidepressant effects occur independently.
Denis Ardid +3 more
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International Clinical Psychopharmacology, 1999
The pathophysiology and effects of antidepressants in the brain are still poorly understood. While it is generally accepted that increasing the levels of monoamine in the brain is an effective way to alleviate depression, the precise neurobiological mechanisms are unclear.
Pedro L. Delgado, Francisco A. Moreno
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The pathophysiology and effects of antidepressants in the brain are still poorly understood. While it is generally accepted that increasing the levels of monoamine in the brain is an effective way to alleviate depression, the precise neurobiological mechanisms are unclear.
Pedro L. Delgado, Francisco A. Moreno
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Pharmacogenetics of Antidepressants
1989The metabolism of tricyclic antidepressants is catalysed by the cytochrome P- 450 family of isozymes. The tertiary amines amitriptyline, imipramine and chlorimipramine are all demethylated to active secondary amines. Desmethylimipramine and nortriptyline, on the other hand, are hydroxylated in aromatic and benzylic positions, respectively.
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