Results 161 to 170 of about 175,215 (214)
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Current Pharmaceutical Design, 2009
The pathophysiology of mood disorders involves several genetic and social predisposing factors, as well as a dysregulated response to a chronic stressor, i.e. chronic pain. Our present view that depression involves a dysfunction of the monoaminergic system is a result of important clinical and preclinical observations over the past 40 years.
Berrocoso, E. +3 more
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The pathophysiology of mood disorders involves several genetic and social predisposing factors, as well as a dysregulated response to a chronic stressor, i.e. chronic pain. Our present view that depression involves a dysfunction of the monoaminergic system is a result of important clinical and preclinical observations over the past 40 years.
Berrocoso, E. +3 more
openaire +3 more sources
Clinics in Geriatric Medicine, 1990
Depressive symptoms are common in the elderly, and depressive illness is the most common of emotional disorders in those of advanced age. This article focuses on the use of antidepressant drugs for the treatment of older depressed patients. To correctly understand the use of antidepressant drugs, it is necessary to first appreciate the medical ...
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Depressive symptoms are common in the elderly, and depressive illness is the most common of emotional disorders in those of advanced age. This article focuses on the use of antidepressant drugs for the treatment of older depressed patients. To correctly understand the use of antidepressant drugs, it is necessary to first appreciate the medical ...
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New England Journal of Medicine, 1965
EIGHT years ago the introduction of iproniazid (Marsilid) and imipramine (Tofranil) opened a new era in the treatment of depression and a new area of psychiatric controversy. Many other antidepressants have since appeared, but, despite numerous investigations, opinions on the most appropriate therapy for depression continue to differ.
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EIGHT years ago the introduction of iproniazid (Marsilid) and imipramine (Tofranil) opened a new era in the treatment of depression and a new area of psychiatric controversy. Many other antidepressants have since appeared, but, despite numerous investigations, opinions on the most appropriate therapy for depression continue to differ.
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Journal of Affective Disorders, 2009
It has been suggested that antidepressants may have neuroprotective abilities but it has newer been investigated lately whether treatment with antidepressants reduces the risk of dementia.Linkage of registers of all prescribed antidepressants and diagnoses of dementia in Denmark during a period from 1995 to 2005.Persons who purchased antidepressants ...
Julie L Forman +2 more
exaly +4 more sources
It has been suggested that antidepressants may have neuroprotective abilities but it has newer been investigated lately whether treatment with antidepressants reduces the risk of dementia.Linkage of registers of all prescribed antidepressants and diagnoses of dementia in Denmark during a period from 1995 to 2005.Persons who purchased antidepressants ...
Julie L Forman +2 more
exaly +4 more sources
Antidepressants and neuroplasticity
Bipolar Disorders, 2002Objective: We review the literature on the cellular changes that underlie the structural impairments observed in brains of animals exposed to stress and in subjects with depressive disorders. We discuss the molecular, cellular and structural adaptations that underlie the therapeutic responses of different classes of ...
Carrol, D'Sa, Ronald S, Duman
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A Compendium of Antidepressants
Clinical Toxicology, 1979This compendium provides a quick reference to available tricyclic antidepressants, monoamine oxidase inhibitors, lithium carbonate, and stimulants. The charts include adult dosages, drug precautions, side effects, interactions with other drugs, and effects on clinical laboratory tests. Basic information on the prevention and management of overdose with
N N, Cain, R M, Cain
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Antidepressants and the Elderly
Journal of the American Geriatrics Society, 1986The pharmacologic treatment of depression in the elderly is often complicated by cardiovascular disease and other medical illnesses. Both the tricyclic antidepressants and the monoamine oxidase (MAO) inhibitors have adverse effects that are potentially dangerous in this age group.
Peabody, CA +2 more
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Glutamatergic antidepressants? The intriguing antidepressant properties of ketamine
Revista de Psiquiatría y Salud Mental (English Edition), 2011This work has been financed by the SAF2007-62378 project and by the Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM)
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Mirtazapine, an antidepressant
American Journal of Health-System Pharmacy, 1998The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage and administration of mirtazapine are reviewed. Mirtazapine is a new anti-depressant that blocks presynaptic alpha 2-adrenergic receptors and postsynaptic serotonin type 2 and type 3 receptors. Mirtazapine has FDA-approved labeling for treatment of depression.
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Pharmacogenetics of Antidepressants
1989The metabolism of tricyclic antidepressants is catalysed by the cytochrome P- 450 family of isozymes. The tertiary amines amitriptyline, imipramine and chlorimipramine are all demethylated to active secondary amines. Desmethylimipramine and nortriptyline, on the other hand, are hydroxylated in aromatic and benzylic positions, respectively.
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