Results 201 to 210 of about 276,787 (297)

Antidepressant Pharmacogenetics [PDF]

open access: bronze, 2017
Ajeet Singh, Chad Bousman
openalex   +1 more source

A “One‐Pot” Metal‐Free Synthesis and Evaluation of Antiproliferative Activity of Diversely Functionalized Pyrrolidine‐2‐Ones

open access: yesJournal of Heterocyclic Chemistry, EarlyView.
A new “one‐pot” metal‐free stereoselective method for the synthesis of novel diversely functionalized pyrrolidine‐2‐ones from N‐alkyl‐ or N‐arylsulfonamidoacetophenones was developed. The majority of obtained compounds possess low micromolar antiproliferative activities.
Samuel Dick   +7 more
wiley   +1 more source

Risk of Seizure Associated With Concomitant Use of Tramadol and Antidepressants in Older Nursing Home Residents. [PDF]

open access: yesNeurology
Wei YJ   +6 more
europepmc   +1 more source

Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander   +4 more
wiley   +1 more source

Reduced prevalence of periodontitis in antidepressant users: Findings from a large‐scale US sample

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis and major depression disorder have been shown to have a bidirectional association. However, the impact of antidepressants, the primary pharmacological treatment for depression, on periodontal health remains unclear.
María Martínez   +3 more
wiley   +1 more source

The Effect of ABCB1 Polymorphisms on the Efficacy of Antidepressants. [PDF]

open access: yesBasic Clin Pharmacol Toxicol
Thorsen SV   +3 more
europepmc   +1 more source

Sciatic Nerve Stimulation Mitigates Depression‐Like Behaviors and Memory Deficits in Stressed Mice

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress causes depression and cognitive decline. With limitations in pharmacotherapy, sciatic nerve stimulation (SNS) offers a promising nondrug alternative. This study aimed to explore the therapeutic efficacy of SNS in mitigating stress‐induced depressive behaviors and memory deficits by focusing on astrocytic dysfunction and cellular ...
Chih‐Hao Tien   +10 more
wiley   +1 more source

Antidepressant drug effects and depression severity: a patient-level meta-analysis.

open access: yesJournal of the American Medical Association (JAMA), 2010
J. Fournier   +6 more
semanticscholar   +1 more source

Machine Learning–Based Classification of Depression Using Inflammatory Biomarkers in Pancreatic Cancer Patients

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Inflammation is a common mediator of pancreatic cancer and depression. This study investigated the predictive value and clinical associations of inflammatory markers and depression in cancer patients using machine learning (ML) and statistical modeling.
Yang‐Chen Shen   +5 more
wiley   +1 more source

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