Results 261 to 270 of about 168,234 (309)
Some of the next articles are maybe not open access.
Antidepressants and neuroplasticity
Bipolar Disorders, 2002Objective: We review the literature on the cellular changes that underlie the structural impairments observed in brains of animals exposed to stress and in subjects with depressive disorders. We discuss the molecular, cellular and structural adaptations that underlie the therapeutic responses of different classes of ...
Carrol, D'Sa, Ronald S, Duman
openaire +2 more sources
A Compendium of Antidepressants
Clinical Toxicology, 1979This compendium provides a quick reference to available tricyclic antidepressants, monoamine oxidase inhibitors, lithium carbonate, and stimulants. The charts include adult dosages, drug precautions, side effects, interactions with other drugs, and effects on clinical laboratory tests. Basic information on the prevention and management of overdose with
N N, Cain, R M, Cain
openaire +2 more sources
Antidepressants and the Elderly
Journal of the American Geriatrics Society, 1986The pharmacologic treatment of depression in the elderly is often complicated by cardiovascular disease and other medical illnesses. Both the tricyclic antidepressants and the monoamine oxidase (MAO) inhibitors have adverse effects that are potentially dangerous in this age group.
Peabody, CA +2 more
openaire +5 more sources
Glutamatergic antidepressants? The intriguing antidepressant properties of ketamine
Revista de Psiquiatría y Salud Mental (English Edition), 2011This work has been financed by the SAF2007-62378 project and by the Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM)
openaire +3 more sources
Mirtazapine, an antidepressant
American Journal of Health-System Pharmacy, 1998The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, and dosage and administration of mirtazapine are reviewed. Mirtazapine is a new anti-depressant that blocks presynaptic alpha 2-adrenergic receptors and postsynaptic serotonin type 2 and type 3 receptors. Mirtazapine has FDA-approved labeling for treatment of depression.
openaire +2 more sources
Pharmacogenetics of Antidepressants
1989The metabolism of tricyclic antidepressants is catalysed by the cytochrome P- 450 family of isozymes. The tertiary amines amitriptyline, imipramine and chlorimipramine are all demethylated to active secondary amines. Desmethylimipramine and nortriptyline, on the other hand, are hydroxylated in aromatic and benzylic positions, respectively.
openaire +2 more sources
Accident Analysis & Prevention, 1985
Although some impairment of skills due to antidepressants has been observed clinically, the impact of antidepressants on traffic safety is at present unknown.
M, Linnoila, T, Seppala
openaire +2 more sources
Although some impairment of skills due to antidepressants has been observed clinically, the impact of antidepressants on traffic safety is at present unknown.
M, Linnoila, T, Seppala
openaire +2 more sources
International Clinical Psychopharmacology, 1995
There are a number of criteria that can be used when selecting an antidepressant. In particular safety criteria are important, and a distinction can be drawn between "safe" and "less safe" antidepressants. The relative safety of different antidepressants has been assessed by looking at answers to the questions: how safe is the drug in overdose; how ...
Swinkels, J. A., de Jonghe, F.
openaire +3 more sources
There are a number of criteria that can be used when selecting an antidepressant. In particular safety criteria are important, and a distinction can be drawn between "safe" and "less safe" antidepressants. The relative safety of different antidepressants has been assessed by looking at answers to the questions: how safe is the drug in overdose; how ...
Swinkels, J. A., de Jonghe, F.
openaire +3 more sources
Antidepressant pharmacogenetics
Current Opinion in Psychiatry, 2014This article reviews recent literature published over the period March 2012-August 2013 on antidepressant pharmacogenetics, with a focus on clinical translation and methodological challenges.Recently, various polymorphisms associated with differential antidepressant efficacy, tolerability, and safety have emerged in association studies, but mixed ...
Singh, Ajeet B. +3 more
openaire +3 more sources
British Journal of Psychiatry, 1992
It is no exaggeration to say that, in the 30 years since antidepressants were introduced, they have revolutionised the management of depression, thus fulfilling, at least for depressive illness, Paracelsus' prophetic wish. We now have a group of drugs which can induce remission in a disease which is disabling and not infrequently fatal.
openaire +2 more sources
It is no exaggeration to say that, in the 30 years since antidepressants were introduced, they have revolutionised the management of depression, thus fulfilling, at least for depressive illness, Paracelsus' prophetic wish. We now have a group of drugs which can induce remission in a disease which is disabling and not infrequently fatal.
openaire +2 more sources