Results 31 to 40 of about 154,417 (308)

Antidepressants vs. Placebo for the Treatment of Functional Gastrointestinal Disorders in Adults: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Psychiatry, 2018
Objective: To integrate high-quality evidence of the efficacy of antidepressants across different subtypes of functional gastrointestinal disorders (FGIDs).Methods: The Medline, PsycINFO, EMBASE, the Cochrane Library, and Chinese local database were ...
Nana Xiong   +4 more
doaj   +1 more source

Concurrent benzodiazepine use in older adults treated with antidepressants in Asia [PDF]

open access: yes, 2017
Background:Little is known about the combined use of benzodiazepines and antidepressants in older psychiatric patients. This study examined the prescription pattern of concurrent benzodiazepines in older adults treated with antidepressants in Asia, and ...
Chee H. Ng   +31 more
core   +1 more source

Understanding Side Effects of Antidepressants: Large-scale Longitudinal Study on Social Media Data

open access: yesJMIR Mental Health, 2021
BackgroundAntidepressants are known to show heterogeneous effects across individuals and conditions, posing challenges to understanding their efficacy in mental health treatment.
Saha, Koustuv   +3 more
doaj   +1 more source

Antidepressants have Anti-inflammatory Effects that may be Relevant to Dermatology: A Systematic Review

open access: yesActa Dermato-Venereologica, 2017
There is increasing evidence of clinically relevant anti-inflammatory effects of monoaminergic antidepressants. PubMed and Ovid databases were searched systematically for the use and efficacy of antidepressants in association with 5 common inflammatory ...
Shirin Eskeland   +2 more
doaj   +1 more source

‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants

open access: yesScandinavian Journal of Primary Health Care, 2021
Background Long-term antidepressant use, much longer than recommended by guidelines, can harm patients and generate unnecessary costs. Most antidepressants are prescribed by general practitioners (GPs) but it remains unclear why they do not discontinue ...
Van Leeuwen Ellen   +5 more
doaj   +1 more source

Molecular mechanisms of rapid-acting antidepressants: New perspectives for developing antidepressants

open access: yesPharmacological Research, 2023
Major depressive disorder (MDD) is a chronic relapsing psychiatric disorder. Conventional antidepressants usually require several weeks of continuous administration to exert clinically significant therapeutic effects, while about two-thirds of the ...
Tao Chen   +15 more
doaj   +1 more source

Methodological Flaws, Conflicts of Interest, and Scientific Fallacies: Implications for the Evaluation of Antidepressants’ Efficacy and Harm

open access: yesFrontiers in Psychiatry, 2017
BackgroundIn current psychiatric practice, antidepressants are widely and with ever-increasing frequency prescribed to patients. However, several scientific biases obfuscate estimates of antidepressants’ efficacy and harm, and these are barely recognized
Michael P. Hengartner
doaj   +1 more source

Antidepressants [PDF]

open access: yes, 2019
Major depression is a severe and prevalent brain disorder with a high disability burden, hence the push for effective treatments. Antidepressants have been around since the 1950s, and although current medications are much more effective than early ones ...

core   +1 more source

Schwangerschaftsdepression und deren Behandlung [PDF]

open access: yes, 2010
Approximately 11% of pregnant women suffer from major depression which requires treatment and if left untreated there are risks of preterm delivery or low birth weight.
Bader, Anja   +3 more
core   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

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