OncoTargets and Therapy, 2019 The discovery that mutations in the EGFR gene are present in up to 50% of patients with lung adenocarcinoma, and the development of highly efficacious EGFR tyrosine kinase inhibitors (TKIs), has revolutionized the way this common malignancy is treated ...
Shouzheng Wang, Junling Li
semanticscholar +1 more source
Saffron the “Red Gold” and Its CNS Activity: A Challenge for Future Applications in Nutraceuticals
Journal of Food Biochemistry, Volume 2024, Issue 1, 2024.Saffron, indicated as “the red gold,” is an extraordinary spice with a unique aroma and organoleptic properties that is largely diffused in food preparation as well as a traditional medicine in many countries of the world. In the last years, several studies have considered this spice for CNS‐based disorders showing its potential usefulness.
Stefania Sut +7 more
wiley +1 more source
Hypericin: Single molecule spectroscopy of an active natural ingredient [PDF]
, 2019 Hypericin can be found in nature in Hypericum perforatum (St. John's Wort) and has become subject of intense biochemical research. Studies report of antidepressive, antineoplastic, antitumor and antiviral activity of hypericin. Among the variety of potential applications hypericin can be used as photosensitizer in photodynamic therapy (PDT), where it ...
arxiv +1 more source
Monte Carlo Sensitivity Analysis for Unmeasured Confounding in Dynamic Treatment Regimes [PDF]
arXiv, 2022 Data-driven methods for personalizing treatment assignment have garnered much attention from clinicians and researchers. Dynamic treatment regimes formalize this through a sequence of decision rules that map individual patient characteristics to a recommended treatment.
arxiv
PSYCHIATRISTS’ PSYCHOTROPIC DRUG PRESCRIPTION PREFERENCES FOR THEMSELVES OR THEIR FAMILY MEMBERS [PDF]
, 2012 Background: Psychiatrists\u27 preference for certain medications is not only determined by their efficacy and side effect profile but may also depend on the psychiatrists\u27 beliefs about specific therapeutic effects based on their own observation and ...
Milan Latas +4 more
core +1 more source
Post-SSRI sexual dysfunction and SSRI induced sexual dysfunction - literature review [PDF]
, 2023 Introduction: Selective serotonin reuptake inhibitors (SSRIs) are one of the most commonly used drugs. One of the most common side effects are those related to sexual function.
Jasłowski, Damian +9 more
core +1 more source
Design and synthesis of novel ligands for Serotonin (5-HT6) receptor and inhibitors of ABCB1 Efflux pump [PDF]
, 2020 Selenium and Biology have a unique relationship. Selenium is an element which exists in several amino acids, including selenocysteine and selenomethionine.
Ali, Wesam
core +1 more source
Altered emotional experiences attributed to antipsychotic medications - A potential link with estimated dopamine D-2 receptor occupancy [PDF]
, 2016 Altered emotional experiences in response to antipsychotics may increase the burden of disease in patients with schizophrenia. In a large cross-sectional study, patients with schizophrenia completed the Subjects Reaction to Antipsychotics questionnaire ...
Bruggeman, Richard +8 more
core +1 more source
Alpha Wavelet Power as a Biomarker of Antidepressant Treatment Response in Bipolar Depression [PDF]
arXiv, 2017 There is mounting evidence of a link between the properties of electroencephalograms (EEGs) of depressive patients and the outcome of pharmacotherapy. The goal of this study was to develop an EEG biomarker of antidepressant treatment response which would require only a single EEG measurement.
arxiv
Pathophysiological concepts of functional dyspepsia and irritable bowel syndrome future pharmacotherapy [PDF]
, 2009 The functional gastrointestinal diseases (FGIDs) are often noticed disturbances. Functional dyspepsja (FD) is the most frequent FGID of the upper part of the gastrointestinal tract while irritable bowel syndrome (IBS) occurs in the lower gastrointestinal
Dobrek, Łukasz, Thor, Piotr
core