Results 111 to 120 of about 60,520 (265)

Cognitive Remediation in Patients With Bipolar Disorder: A Randomized Trial by Sequential tDCS and Navigated rTMS Targeting the Primary Visual Cortex

CNS Neuroscience &Therapeutics, Volume 30, Issue 12, December 2024.
All patients underwent a 3‐week intervention of combined electromagnetic stimulation. Scale assessments and magnetic resonance imaging data collection were performed before and after the intervention, followed by scale assessments at the eighth week.
Hetong Zhou, Minmin Wang, Ting Xu, Xiaomei Zhang, Xudong Zhao, Lili Tang, Pengfei Zhao, Dandan Wang, Jianbo Lai, Fei Wang, Shaomin Zhang, Shaohua Hu   +11 more
wiley   +1 more source

Assessment of the 3-substituted thietane-1,1-dioxide derivative antidepressant effect using rat model of depression induced by reserpine

Research Results in Pharmacology
Introduction: 3-ethoxythietane-1,1-dioxide (3ETD) is a novel molecule that has demonstrated significant antidepressant properties when administered intraperitoneally (i.p.) to mice once or repeatedly.
Irina L. Nikitina, Gulnara G. Gaisina, Elena E. Klen, Lyubov A. Tkachenko   +3 more
doaj   +1 more source

Multiply robust estimators in longitudinal studies with missing data under control-based imputation [PDF]

arXiv, 2021
Longitudinal studies are often subject to missing data. The ICH E9(R1) addendum addresses the importance of defining a treatment effect estimand with the consideration of intercurrent events. Jump-to-reference (J2R) is one classically envisioned control-based scenario for the treatment effect evaluation using the hypothetical strategy, where the ...
arxiv  

Minocycline reduces mechanical allodynia and depressive-like behaviour in type-1 diabetes mellitus in the rat [PDF]

, 2017
A common and devastating complication of diabetes mellitus is painful diabetic neuropathy (PDN) that can be accompanied by emotional disorders such as depression.
Almeida, Armando, Amorim, Diana, Braga, Antonio, Braganca, Rui, Pertovaara, Antti, Pinto-Ribeiro, Filipa, Puga, Sonia   +6 more
core   +1 more source

A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2R,6R)‐Hydroxynorketamine in Healthy Volunteers

Clinical Pharmacology &Therapeutics, Volume 116, Issue 5, Page 1314-1324, November 2024.
(R,S)‐Ketamine (ketamine) is a dissociative anesthetic that also possesses analgesic and antidepressant activity. Undesirable dissociative side effects and misuse potential limit expanded use of ketamine in several mental health disorders despite promising clinical activity and intensifying medical need.
Shruti M. Raja, Jeffrey T. Guptill, Michelle Mack, Marni Peterson, Stephen Byard, Robert Twieg, Lynn Jordan, Natalie Rich, Richard Castledine, Samuel Bourne, Martin Wilmshurst, Sarah Oxendine, Satya G.C. Avula, Helen Zuleta, Paul Quigley, Sheila Lawson, Stephen J. McQuaker, Reza Ahmadkhaniha, Lawrence G. Appelbaum, Kevin Kowalski, Chineta T. Barksdale, Brandon T. Gufford, Asaad Awan, Alfredo R. Sancho, Max C. Moore, Karim Berrada, Gregory B. Cogan, Jesse DeLaRosa, Jeanne Radcliffe, Maryland Pao, Michelle Kennedy, Quentin Lawrence, Lisa Goldfeder, Leslie Amanfo, Panos Zanos, Jessica R. Gilbert, Patrick J. Morris, Ruin Moaddel, Todd D. Gould, Carlos A. Zarate Jr, Craig J. Thomas   +40 more
wiley   +1 more source

Hypericin: Single molecule spectroscopy of an active natural ingredient [PDF]

, 2019
Hypericin can be found in nature in Hypericum perforatum (St. John's Wort) and has become subject of intense biochemical research. Studies report of antidepressive, antineoplastic, antitumor and antiviral activity of hypericin. Among the variety of potential applications hypericin can be used as photosensitizer in photodynamic therapy (PDT), where it ...
arxiv   +1 more source

Low‐dose amitriptyline: A potential therapeutic option for chronic pain in older people

British Journal of Clinical Pharmacology, Volume 91, Issue 3, Page 921-922, March 2025.
Takayuki Suga, Trang Thi Huyen Tu, Motoko Watanabe, Takahiko Nagamine, Akira Toyofuku   +4 more
wiley   +1 more source

Multiple Acyl‐Coenzyme A Dehydrogenase Deficiency Is Associated with Sertraline Use – Is There an Acquired Form?

Annals of Neurology, Volume 96, Issue 4, Page 802-811, October 2024.
Objective Multiple acyl‐coenzyme A dehydrogenase deficiency (MADD) is a disorder of fatty acid oxidation and considered an inborn error of metabolism. In recent years, we have diagnosed an increasing number of patients where, despite extensive investigation, no disease‐causing mutations have been found. We therefore investigated a cohort of consecutive
Sofie Sunebo, Hanna Appelqvist, Bo Häggqvist, Olof Danielsson   +3 more
wiley   +1 more source

Warfarin: pharmacological profile and drug interactions with antidepressants

Einstein (São Paulo), 2012
Oral anticoagulants are among the drugs with the greatest number of drug interactions. The concomitant use of several medications is a common practice in patients with cardiovascular problems, who often also present with depression; therefore, the ...
Juliana Souto Teles, Ellen Yukie Fukuda, David Feder   +2 more
doaj  

The Impact of Psychiatric Distress on Co-morbid Medical Illness: A Problem Based Learning (PBL) Case

MedEdPORTAL, 2006
Introduction Medical students are often unaware of the relationship between mood/anxiety disorders and cardiovascular disease (e.g., the behavioral and biological mechanisms through which depression might lead to, or exacerbate coronary artery disease ...
Jason Rosenstock
doaj   +1 more source