Results 121 to 130 of about 60,520 (265)

Latent classes of nonresponders, rapid responders, and gradual responders in depressed outpatients receiving antidepressant medication and psychotherapy [PDF]

open access: yes, 2015
BackgroundWe used growth mixture modeling (GMM) to identify subsets of patients with qualitatively distinct symptom trajectories resulting from treatment. Existing studies have focused on 12-week antidepressant trials.
Bagby, Michael   +5 more
core   +2 more sources

A target trial emulation comparing the antidepressant effectiveness of selective serotonin reuptake inhibitors (SSRIs) highlighting the importance of patent‐related confounding by indication

open access: yesActa Psychiatrica Scandinavica, Volume 150, Issue 4, Page 198-208, October 2024.
Abstract Background The comparative effectiveness of selective serotonin reuptake inhibitors (SSRIs) has been subjected to relatively little research. However, a recent study based on target trial emulation suggested that sertraline may be more effective than escitalopram.
Christopher Rohde   +2 more
wiley   +1 more source

Alpha Wavelet Power as a Biomarker of Antidepressant Treatment Response in Bipolar Depression [PDF]

open access: yesarXiv, 2017
There is mounting evidence of a link between the properties of electroencephalograms (EEGs) of depressive patients and the outcome of pharmacotherapy. The goal of this study was to develop an EEG biomarker of antidepressant treatment response which would require only a single EEG measurement.
arxiv  

Effectiveness of a recent topical sialogogue in the management of drug-induced xerostomia [PDF]

open access: yes, 2011
Objectives: Use of certain drugs is the most common aetiology of xerostomia. Systemic sialogogues provide a longer effect than topic ones, but also induce relevant side effects. Topical sialogogues, as malic acid, allow a safe use as they
Aguilar Salvatierra, Antonio   +3 more
core   +1 more source

Pharmacological Studies with Nialamide, A New Antidepressant Agent

open access: yesExperimental Biology and Medicine, 1959
SummaryNialamide was a potent monoamine oxidase inhibitor by both in vitro and in vivo test. Its potency relative to that of iproniazid varies from 3:1 to 12:1 depending on test and species used. Nialamide was also shown to be qualitatively different from other MAO inhibitors in some of its pharmacological actions, factors which may explain absence of ...
S. Y. P'An   +3 more
openaire   +3 more sources

Resocialization mitigates depressive behaviors induced by social isolation stress in mice: Attenuation of hippocampal neuroinflammation and nitrite level

open access: yesBrain and Behavior, Volume 14, Issue 6, June 2024.
Abstract Background and aim Social isolation stress (SIS) is a stressor known to trigger depressive behaviors. Psychiatric disorders are associated with neurobiological changes, such as neuroinflammation and an increase in nitric oxide (NO) signaling. Despite the well‐established detrimental effects of SIS and the involvement of neuroinflammation and ...
Hossein Amini‐Khoei   +2 more
wiley   +1 more source

A Skew Normal Model of the Dose-Effect Relation in Pharmacology [PDF]

open access: yesarXiv, 2015
This paper deals with a skew-normal model of the relation between a dose $d > 0$ and a quantitative measure $E(d)$ of an effect of the administered drug. Precisely, $E(d)$ is a measure of the therapeutic response or a measure of a side-effect. Some existing and additional properties of the logistic functions are proved, and a skew-normal model of the ...
arxiv  

(R)-2,5-Dimethoxy-4-Iodoamphetamine [(R)-Doi] Influences Coping Strategies to an Escapable Social Stress [PDF]

open access: yes, 2021
Depressive mood disorders are a leading cause of disability worldwide and pharmacological treatments for these disorders are inadequate, requiring new compounds with greater efficacy be investigated.
Krupp, Kevin Thomas
core   +1 more source

Prescribing Pattern of Antidepressant Drugs among General Practitioners and Psychiatrists: a study from Iran

open access: yesRussian Open Medical Journal, 2013
Aim – This study was aimed to investigate the pattern of antidepressant drugs prescription among general practitioners and psychiatrists of Kerman/Iran with the goal of preventing irrational drug use.
Hamid Reza Motevallyzadeh   +3 more
doaj  

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