Results 11 to 20 of about 34,352 (306)
Research and Practice in Thrombosis and Haemostasis, 2021 Background Bivalent thrombin‐binding aptamers (TBAs) have great potential for the treatment of thrombosis because they exhibit high anticoagulant activity, and their complementary single‐stranded DNA (ssDNA) sequences work as an antidote.
Toru Yoshitomi +3 more
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Anticoagulants: dose control methods and inhibitors
Акушерство, гинекология и репродукция, 2022 These days, anticoagulants are in great demand. They are used as a prophylaxis for thromboembolic complications in various diseases and conditions in general therapeutic practice, cardiology, neurology, as well as obstetrics to manage high-risk ...
V. O. Bitsadze +9 more
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Optimization of a nicotine degrading enzyme for potential use in treatment of nicotine addiction
BMC Biotechnology, 2019 Background Smoking and tobacco use continue to be the largest preventable causes of death globally. A novel therapeutic approach has recently been proposed: administration of an enzyme that degrades nicotine, the main addictive component of tobacco ...
Thomas Thisted +9 more
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Iterative thermodynamic modelling—Part 1: A theoretical scoring technique and a computer program ( Bingo‐Antidote ) [PDF]
, 2020 This paper introduces the software solution Bingo‐Antidote for thermodynamic calculations at equilibrium based on iterative thermodynamic models. It describes a hybrid strategy combining the strength of Gibbs energy minimization (GEM) and inverse ...
Pierre Lanari +3 more
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A neutralizable dimeric anti-thrombin aptamer with potent anticoagulant activity in mice
Molecular Therapy: Nucleic Acids, 2023 Heparin-induced thrombocytopenia (HIT) is a complication caused by administration of the anticoagulant heparin. Although the number of patients with HIT has drastically increased because of coronavirus disease 2019 (COVID-19), the currently used thrombin
Masanobu Nagano +6 more
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Intravenous Lipid Emulsion as an Adjuvant Therapy of Acute Antipsychotic Poisoning: A randomized Controlled Trial [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2022 Background: Antipsychotics toxicity is one of the top five substances most frequently included in human poisoning. Various case reports documented successful use of intravenous lipid emulsion (ILE) in the management of acute antipsychotics poisoning. Aim:
Heba Lashin +3 more
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Federalism as an effective antidote to terrorism [PDF]
, 2010 Many governments as well as terrorist experts see the use of military and police forces as the only way to effectively counter terrorism. The most effective negative sanctions are considered to be military strikes, aggressive actions (including ...
Frey, Bruno S +2 more
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BMC Biotechnology, 2018 Background The bacterial nicotine-degrading enzyme NicA2 isolated from P. putida was studied to assess its potential use in the treatment of tobacco dependence. Results Rats were pretreated with varying i.v.
Paul R. Pentel +6 more
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Treatment of Permethrin Toxicosis in Cats by Intravenous Lipid Emulsion
Toxics, 2022 Background: In this study, the clinical response to treatment with intravenous lipid emulsion (ILE) for nine cats intoxicated with permethrin has been described.
Simona Di Pietro +5 more
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Trends in Pharmacological Sciences, 2002 This very welcome book on antidotes by Flanagan and Jones from Guy's and St Thomas' NHS Trust is a paperback, but fairly comprehensive text, on antidotes. It includes a chapter on chemical warfare agents by myself and Bob Maynard, on which I will not comment, except to say that, sadly, this chapter may prove a selling point at …
openaire +3 more sources