Results 201 to 210 of about 34,352 (306)

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Intraoperative peripheral intravenous complications in adults: a summary of evidence for prevention and management of infiltration/extravasation. [PDF]

Front Med (Lausanne)
Liu H, Zeng Q, Zeng X, Lu X, Xiao B, Cheng Y, Liu Y, Yang C, Yang C.   +8 more
europepmc   +1 more source

Role of the Emergency Medicine Pharmacist in the Management of Boarding Patients: An Opinion of the Emergency Medicine Practice and Research Network of the American College of Clinical Pharmacy Endorsed by the SAEM Academy of Emergency Medicine Pharmacists and the Society of Emergency Medicine Pharmacists

JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY, Volume 9, Issue 6, June 2026.
ABSTRACT As emergency department (ED) crowding and patient boarding reach critical levels nationwide, the role of the emergency medicine pharmacist (EMP) must be both defined and safeguarded. While EMPs are increasingly valued for their contributions to acute care, their responsibilities often unintentionally expand during periods of operational strain,
Brian W. Gilbert, David E. Zimmerman, Alyssa Robertson, Gavin D. Jones, Bryan J. Gendron, Jessica L. Corio, Sarah S. Harlan, Kellyn Engstrom, Alexa Maisenbach, Kerry Anne Rambaran, Kevin J. Mercer, Ryan Feldman, Curtis Geier, Donna Shuler Truoccolo, Kyle A. Weant, Heather Blue   +15 more
wiley   +1 more source

Trends in antidote use in France from 2015 to 2021: a nationwide poison centers study. [PDF]

Sci Rep
Pouget AM, Blanc-Brisset I, Guillotin S, Gerussi M, Pélissier F, French PCC Research Group, Vodovar D, Delcourt N.   +7 more
europepmc   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

Journal of Applied Toxicology, Volume 46, Issue 6, Page 1856-1870, June 2026.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz, Bayram Göktaş, İlker Ateş, Mustafa Çelik   +3 more
wiley   +1 more source

Case report: acute phosphine inhalation poisoning in a patient with Down's syndrome. [PDF]

Int J Emerg Med
Yu X, Zhang J, Xu J, Dong K, Jin L, Wen X, Zhou X.   +6 more
europepmc   +1 more source

N‐Acetylcysteine Attenuates Mancozeb‐Induced Hepatorenal Injury by Modulating Oxidative Stress, Inflammatory Signaling, and Apoptotic Pathways in Rats

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
N‐acetylcysteine (NAC) attenuated mancozeb‐induced hepatotoxicity and nephrotoxicity in rats by reducing oxidative stress, inflammation, and apoptosis. NAC restored antioxidant balance and suppressed inflammatory and apoptotic signaling pathways, suggesting a protective role against mancozeb‐related hepatorenal injury. ABSTRACT Mancozeb (MNZ), a widely
Ali Çakırlı, Metin Deniz Karakoç, Özlem Özmen, Münevver Nazlıcan Kaplan, Osman Çiftçi   +4 more
wiley   +1 more source

Anticoagulation Stewardship Program in the DOAC Era. [PDF]

J Clin Med
Ng JX, Tan SC, Koh PL, Yap ES.
europepmc   +1 more source

Evaluation of Hemoadsorption Capacity of the CytoSorb Adsorber for Toxic Doses of Diclofenac and Meloxicam in Porcine Plasma

Journal of Clinical Apheresis, Volume 41, Issue 3, June 2026.
ABSTRACT The objective of this in vitro experimental was to determine the utility of hemoadsorption (HA) using the CytoSorb adsorber to remove meloxicam and diclofenac from porcine plasma. For this purpose 12 1‐L aliquots of porcine plasma, 6 units were spiked with 293 μg/mL (262–320 μg/mL) diclofenac and 6 with 42.8 μg/mL (41.4–44.7 μg/mL) meloxicam ...
Bettina Giani, René Dörfelt, Katrin Hartmann, Florian Sänger   +3 more
wiley   +1 more source