Results 171 to 180 of about 12,545 (301)

Analysis of Two New Flavonoid Glycosides From Zanha golungensis Hiern With COX Inhibition Activity: Structural Elucidation, DFT Calculations, In Vitro and Molecular Docking Assessment

Analytical Science Advances, Volume 7, Issue 1, June 2026.
Zanha golungensis contains phenolic compounds amongst which are two previously undescribed flavonoid glycosides as shown in this study. The constituents of this plant exhibit anti‐inflammatory activity by inhibiting cyclooxygenases (COX‐1 and COX‐2).
Jean Zeuikena, Romeo Toko Feunaing, Alfred Ngenge Tamfu, Abel Joel Yaya Gbaweng, Celine Henoumont, Sophie Laurent, El Hassane Anouar, Emmanuel Talla   +7 more
wiley   +1 more source

Complicated Catastrophic Calcium Gluconate Extravasation: Post-Surgical Graft Calcinosis Cutis. [PDF]

Clin Case Rep
Abtahi-Naeini B, Rastegarnasab F, Kakavand N.   +2 more
europepmc   +1 more source

Silymarin and Its Isolated Flavanonol Lignans Are Liver X Receptor Antagonists

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
Despite its long tradition in the treatment of liver‐related ailments, the precise mode of action of the milk thistle fruit extract remains vague. Here we identified liver X receptor as a molecular target of silymarin, a mixture of bioactive compounds from milk thistle extract, and its major flavanonol lignan components, which account for their anti ...
Nils C. Bandomir, Astrid Kaiser, Felix F. Lillich, Pascal Heitel   +3 more
wiley   +1 more source

Discordance in Drug-Drug Interaction Alerts for Antidotes: Comparative Analysis of Electronic Databases and Interpretive Insights from AI Tools. [PDF]

Drug Des Devel Ther
Yaowaluk T, Tangpanithandee S, Techapichetvanich P, Khemawoot P.   +3 more
europepmc   +1 more source

Trends and variation in the use of andexanet alfa for the reversal of direct oral anticoagulants in NHS trusts in England

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1607-1613, June 2026.
Abstract Aims Andexanet alfa was recommended by the National Institute for Health and Clinical Excellence (NICE) as an option in the management of life‐threatening gastrointestinal bleeding in patients taking apixaban or rivaroxaban in May 2021. A recent UK‐wide survey of local hospital protocols for the use of andexanet alfa suggested that practice ...
Louis Fisher, Richard Buka, Rosalind Byrne, Stephen Black, Helen J. Curtis, Christopher Wood, Andrew Brown, Sebastian Bacon, Richard Croker, Ben Goldacre, Brian MacKenna, Victoria Speed   +11 more
wiley   +1 more source

Missed opportunities in methanol poisoning: a qualitative exploration of the socio-material practices of health professionals responding to acute methanol poisoning in Bangladesh. [PDF]

BMJ Open
Perkins JE, Sørensen JB, Islam MS, Hovda KE, Chowdhury FR, Ghose A, Rahman ASMM, Eddleston M, Street A.   +8 more
europepmc   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Recurrent evolution of selfishness from an essential tRNA synthetase in Caenorhabditis tropicalis. [PDF]

Nat Ecol Evol
Tikanova P, Ross JJ, Hagmüller A, Pühringer F, Pliota P, Krogull D, Stefania V, Hunold M, Koreshova A, Koller A, Ostapchuk I, Okweri J, Gokcezade J, Duchek P, Dong G, Ben-David E, Burga A.   +16 more
europepmc   +1 more source

Doctors' knowledge of the appropriate use and route of administration of antidotes in the management of recreational drug toxicity

Background: Specific antidotes (eg, naloxone, flumazenil, cyproheptadine and benzodiazepines) are available for the management of certain recreational drug-induced toxicities.
J. R. H. Archer (21281618), H. Ovaska (21281615), S. Lidder (21281612), P. I. Dargan (7681430), A. L. Jones (17217532), D. M. Wood (21281597), S. L. Greene (21281594)   +6 more
core  

Clinical Profiles and Therapeutic Interventions in Occult Paraquat Poisoning: A Comparative Report of Two Cases

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Delayed diagnosis invariably worsens outcomes in occult paraquat poisoning regardless of exposure route. Implement early urinary screening for suspected cases. Tailor antioxidant and anti‐fibrotic timing to toxicokinetic patterns to mitigate irreversible pulmonary damage.
Minhong Zhao, Shuai Zhou, Ying Zhang, Eryan Yuan, Min Peng, Ying Gao   +5 more
wiley   +1 more source