Results 91 to 100 of about 35,117 (307)

Efficacy and safety of rimegepant for the acute treatment of migraine in Japan: A dose‐ranging, double‐blind, randomized controlled trial

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary: This randomized trial was designed to test the effectiveness and safety of rimegepant for the acute treatment of migraine among adults in Japan. Results indicated that rimegepant was more effective than placebo, and the 75 mg dose was observed to be more effective than the 25 mg dose.
Koichi Ikeda   +11 more
wiley   +1 more source

Diphenidol Has No Actual Broad Antiemetic Activity in Dogs and Ferrets

open access: yesJournal of Pharmacological Sciences, 2004
Previous studies showed that diphenidol was effective on emetogens-induced pica, eating of non-nutritive substances, in rats, a model analogous to emesis in other species.
Hiroe Nakayama   +6 more
doaj   +1 more source

A 52‐week open‐label extension study to evaluate the safety and efficacy of oral rimegepant for the preventive treatment of migraine

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To assess the safety, tolerability, and treatment effects of rimegepant 75 mg every other calendar day (EOD) for the preventive treatment of migraine in a 52‐week, open‐label extension (OLE) study. Background Rimegepant is an oral small molecule calcitonin gene–related peptide receptor antagonist approved for the acute treatment of ...
David Kudrow   +3 more
wiley   +1 more source

Evaluation of the Antiemetic Effect of Valeriana officinalis Root Extract in Young Chicken

open access: yesJournal of Medicinal Plants, 2011
Background: In traditional medicine, the roots and rhizomes of Valeriana officinalis (Valerian) have been used to decrease gastrointestinal tract motility in intestinal spasms, colic and gastrointestinal disorders of nervous origin.
H Hosseinzadeh, MR Jaafari, BH Parhiz
doaj  

Reduction of opioid and barbiturate use following initiation of rimegepant for migraine in the United States

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective The primary objective of this study was to evaluate opioid and barbiturate utilization before and after the first prescription of the calcitonin gene–related peptide receptor antagonist rimegepant in individuals with migraine. Background Although not recommended in migraine treatment guidelines, opioids and barbiturates are often ...
Noah Rosen   +6 more
wiley   +1 more source

Amyloidosis for the Gastroenterologist: A Comprehensive Systematic Review of Diagnosis and Management of Gastrointestinal Manifestations

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Amyloidosis is a rare, multisystem disorder characterized by extracellular deposition of misfolded protein fibrils. Gastrointestinal (GI) amyloidosis is uncommon but under‐recognized due to nonspecific symptoms, but early diagnosis is critical to improve quality of life and prognosis.
Myo Jin Tang   +3 more
wiley   +1 more source

Antiemetic Prescription Fills in Pregnancy: A Drug Utilization Study Among 762,437 Pregnancies in Norway

open access: yesClinical Epidemiology, 2021
Marleen MHJ van Gelder,1,2 Hedvig Nordeng3,4 1Department for Health Evidence, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands; 2Radboud REshape Innovation Center, Radboud University Medical Center ...
van Gelder MMHJ, Nordeng H
doaj  

Gabapentin for Postoperative Vomiting in Children Requiring Posterior Fossa Tumor Resection

open access: yesPediatrics and Neonatology, 2015
Gabapentin is well known for its pain control and antiepileptic effect, but its antiemetic effect is poorly investigated. Here we report on effective gabapentin use for refractory vomiting after craniotomy in two children with medulloblastoma in the ...
Ko-Chun Tsai, Yung-Li Yang, Pi-Chuan Fan
doaj   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

open access: yesJournal of the American Geriatrics Society, EarlyView.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao   +11 more
wiley   +1 more source

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