Results 131 to 140 of about 33,865 (284)

Tirzepatide 10 and 15 mg versus semaglutide 2.4 mg in people with obesity or overweight with type 2 diabetes: An indirect treatment comparison

Diabetes, Obesity and Metabolism, Volume 27, Issue 7, Page 3757-3765, July 2025.
Abstract Aims Tirzepatide and semaglutide demonstrated clinically meaningful weight reduction in people with obesity or overweight and type 2 diabetes (T2D) in SURMOUNT‐2 and STEP 2 clinical trials, respectively. In the absence of head‐to‐head trials, this study compared the efficacy of tirzepatide 10 and 15 mg with semaglutide 2.4 mg using an indirect
Emily R. Hankosky, Xuanyao He, Raleigh Malik, Julia Fraseur Brumm, Fangyu Wang, Anthony Niemeyer, Xiaotian M. Zhang, W. Timothy Garvey   +7 more
wiley   +1 more source

Antiemetic efficacy of metoclopramide when included in a patient‐controlled analgesia infusion [PDF]

, 1994
A. D. Walder, A. R. Aitkenhead
openalex   +1 more source

Identifying Barriers and Enablers for Nurse‐Initiated Care for Designing Implementation at Scale in Australian Emergency Departments: A Mixed Methods Study

Journal of Clinical Nursing, Volume 34, Issue 7, Page 2718-2736, July 2025.
ABSTRACT Aim The aim of this study was to (i) identify barriers and enablers and (ii) inform mitigating or strengthening strategies for implementing nurse‐initiated care protocols at scale in emergency departments (EDs). Design Embedded mixed methods. Methods The study included four clusters with a total 29 EDs in NSW, Australia.
Sarah Kourouche, Julie Considine, Ling Li, Margaret Murphy, Ramon Z. Shaban, Mary K. Lam, Saartje Berendsen Russell, Margaret Fry, Christina Aggar, Michael M. Dinh, Amith Shetty, Timothy Shaw, Radhika V. Seimon, Nanda R. Aryal, James A. Hughes, Wayne Varndell, Kate Curtis   +16 more
wiley   +1 more source

Cost-effectiveness analysis of tropisetron vs. chlorpromazine-dexamethasone in the control of acute emesis induced by highly emetogenic chemotherapy in children [PDF]

, 1999
To perform a cost-effectiveness analysis (CEA) between a standard antiemetic regimen-chlorpromazine + dexamethasone (CPM-DEX)- and a 5-HT3 receptor antagonist-tropisetron (TROP)--in the control of acute emesis induced by highly ...
Giraldez, J. (J.), Jimenez, M. (Miguel), Sierrasesumaga, L. (Luis), Tejedor, I. (I.)   +3 more
core  

Treatment of Hypovitaminosis D With Cholecalciferol in Dogs With Protein‐Losing Enteropathies: A Randomized, Double‐Blind, Placebo‐Controlled, Clinical Trial

Journal of Veterinary Internal Medicine, Volume 39, Issue 4, July/August 2025.
ABSTRACT Background The effects of vitamin D supplementation are unknown in dogs with protein‐losing enteropathy (PLE). Objective To evaluate the safety, efficacy, and clinical benefit of orally administered cholecalciferol in dogs with PLE and decreased serum concentrations of 25OHD.
Sara A. Jablonski, Sarah B. Shropshire, Victoria E. Watson, Alison C. Manchester, Harry Cridge, Elizabeth M. Lennon, M. Katherine Tolbert   +6 more
wiley   +1 more source

Perioperative Intravenous Lidocaine Infusion Therapy as an Adjunct to Multimodal Analgesia for Adolescent Idiopathic Scoliosis Surgical Correction: A Double‐Blind Randomized Controlled Trial

Pediatric Anesthesia, Volume 35, Issue 7, Page 552-561, July 2025.
ABSTRACT Background Posterior spinal instrumentation and fusion is a common surgical correction for adolescent idiopathic scoliosis. Preventative multimodal analgesia, including opioids, is required to minimize postoperative pain, but opioids are associated with dose‐dependent side effects that may disrupt recovery.
Jessica Luo, Nicholas West, Samantha Pang, Aanisah Golam, Erin Adams, Matthias Görges, Roxane R. Carr, Firoz Miyanji, Gillian R. Lauder   +8 more
wiley   +1 more source

Impact of Drug–Drug Interactions on Clinical Outcomes in Metastatic Melanoma Patients Treated With Combined BRAF/MEK Inhibitors: A Real‐World Study

Pigment Cell &Melanoma Research, Volume 38, Issue 4, July 2025.
ABSTRACT The unique pharmacokinetics of BRAF and MEK inhibitors make patients vulnerable to drug–drug interactions (DDIs), which may compromise treatment efficacy in metastatic melanoma. This study evaluates the impact of DDIs on clinical outcomes in patients with metastatic melanoma treated with BRAF/MEK inhibitors.
Silvia Mezi, Andrea Botticelli, Giulia Pomati, Simone Scagnoli, Giulia Fiscon, Federica de Galitiis, Francesca Romana di Pietro, Sofia Verkhovskaia, Sasan Amirhassankhani, Giovanna Gentile, Maurizio Simmaco, Bjoern Gohlke, Robert Preissner, Daniele Santini, Paolo Marchetti   +14 more
wiley   +1 more source

Intravenous buspirone for the prevention of postoperative nausea and vomiting [PDF]

, 2018
Rationale: Buspirone, a partial 5HT1A agonist and D2 and D3 antagonist, has shown promising antiemetic efficacy when given parenterally in animal models, but its efficacy for the prevention of postoperative nausea and vomiting (PONV) is unknown ...
Apfel, Christian, Chassard, Dominique, Diemunsch, Pierre, Eberhart, Leopold, Fox, Gabriel, Gan, Tong, Kranke, Peter, Lebuffe, Gilles, Minkowitz, Harold, Röhm, Kerstin, Tramèr, Martin, Wallenborn, Jan   +11 more
core  

Is ondansetron a less effective antiemetic against moderately emetic as compared with highly emetic chemotherapy? [see comments] [PDF]

, 1992
JW Dundee, CM McMillan, Jing Yang, Peter M. C. Wright   +3 more
openalex   +1 more source

Diphenidol Has No Actual Broad Antiemetic Activity in Dogs and Ferrets

Journal of Pharmacological Sciences, 2004
Previous studies showed that diphenidol was effective on emetogens-induced pica, eating of non-nutritive substances, in rats, a model analogous to emesis in other species.
Hiroe Nakayama, Hisashi Yamakuni, Aya Nakayama, Yasue Maeda, Katsunori Imazumi, Masahiko Matsuo, Seitaro Mutoh   +6 more
doaj