Results 131 to 140 of about 21,842 (260)

Acute Drug‐Induced Liver Injury After Four Doses of Nitrofurantoin, as Evaluated for Causality Using the Updated RUCAM, With a Disproportionate Rise in AST—A Novel Case Report

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Drug‐induced liver injury remains a severe but underdiscussed adverse effect of nitrofurantoin. This case uniquely describes hepatic injury occurring after four doses of nitrofurantoin, with a disproportionate rise in AST and rapid complete recovery following discontinuation of the drug. A RUCAM score of six supports the probability of DILI.
Mahir H. Sampat
wiley   +1 more source

Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose

open access: yesDrug Testing and Analysis, Volume 18, Issue 7, Page 877-892, July 2026.
A single oral dose of diphenhydramine and cyclizine can be quantified in human head hair for a minimum of 5 months and, in certain cases, for up to 1 year following intake. Among 12 study participants, the measured concentrations ranged from 0 to 610 pg/mg within 1 year post‐intake.
Jan Bílek   +3 more
wiley   +1 more source

Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT3 receptor antagonists [PDF]

open access: yes, 2010
J. A. Rudd   +7 more
core   +1 more source

A Prospective Evaluation of Glucagon Stimulation Test Safety in Adults With Chronic Moderate‐to‐Severe Traumatic Brain Injury

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
The glucagon stimulation test demonstrates a favourable safety profile in adults with chronic moderate‐to‐severe traumatic brain injury, with transient, non‐severe adverse effects and no serious complications. ABSTRACT Introduction Growth hormone deficiency (GHD) is a common and clinically significant consequence of moderate‐to‐severe traumatic brain ...
Corey Snyder   +2 more
wiley   +1 more source

Unplanned Post‐Operative Pediatric Intensive Care Unit Admissions After Elective Upper Airway Procedures: A Retrospective Case–Control Study

open access: yesPediatric Anesthesia, Volume 36, Issue 7, Page 792-799, July 2026.
ABSTRACT Background Elective pediatric upper airway procedures are generally safe; however, some patients require unplanned pediatric intensive care unit admission, increasing care complexity. Aims To identify perioperative risk factors associated with unplanned pediatric intensive care unit admission following elective pediatric upper airway surgery ...
Hayes Stancliff   +5 more
wiley   +1 more source

Clinical Remission of an Unresectable Presumptive Haemangiosarcoma in a Dog Treated With Toceranib, Piroxicam, and Propranolol: A Case Report

open access: yesVeterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Radiographic remission of a presumptive unresectable haemangiosarcoma treated with toceranib, piroxicam, and propranolol. In a dog with ACVIM Stage B2 myxomatous mitral valve disease where doxorubicin‐based chemotherapy was contraindicated, this multimodal regimen achieved marked tumour reduction and radiographic disappearance.
Woo Dae Park
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

open access: yesAngewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Optimizing antiemetic therapy in multiple-day and multiple cycles of chemotherapy

open access: yes, 2008
PURPOSE OF REVIEW: Only a few studies have investigated the effect of antiemetic therapy in patients treated with multiple-day or multiple cycles of chemotherapy.
Ellebaek, E., Herrstedt, J.
core  

General Anaesthesia Versus Spinal Anaesthesia for Outpatient Total Hip and Knee Arthroplasty: A Randomised Trial Protocol

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Introduction Same‐day discharge after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) is increasing, but the optimal anaesthetic technique for outpatient pathways remains uncertain. Neuraxial anaesthesia is widely recommended based on observational evidence, whereas fast‐track programmes using short‐acting total ...
Erik Noppa   +6 more
wiley   +1 more source

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