Results 131 to 140 of about 23,984 (264)

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, Volume 92, Issue 10, Page 3365-3374, October 2026.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

Next‐Generation Sequencing‐Based Molecular Profiling and Management of Advanced Solid Tumors: A Real‐World Experience in a Community‐Based Academic Cancer Center

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Advances in molecular and cell biology have led to a paradigm shift in cancer management. We implemented next‐generation sequencing (NGS) at our community‐based academic cancer center over a decade ago. We sought to optimize the use of genomics and understand its impact in identifying actionable genomic alterations to determine ...
Gayathri Moorthy, Annette Sereika, Karen Kaul, Megan Parilla, Mir B. Alikhan, Michael Bouma, Dyson Wake, Peter J. Hulick, Henry M. Dunnenberger, Linda M. Sabatini, Mathew Yang, Kathy A. Mangold, Erin Proctor, Nicholas Evans, Nicholas Miller, Donald L. Helseth Jr, Darryck Maurer, Justin Brueck, Janardan Khandekar, Bruce Brockstein   +19 more
wiley   +1 more source

Granisetron as antiemetic therapy in children with cancer

The safety and efficacy of the new 5HT-3 antagonist granisetron as an antiemetic in children with cancer was evaluated in 40 children at a single doses of 40 mug/kg. No adverse affects attributable to the granisetron were noted.
L., A. W., O. B., D. M., J., Craft, Murdoch, Campbell, Eden, Shaw, Pierce, Price, Upward, R., P.   +14 more
core   +3 more sources

Impact of antiemetic steroid use on survival in small cell lung cancer patients receiving immune checkpoint inhibitors and chemotherapy

Scientific Reports
Immune checkpoint inhibitors (ICIs) combined with conventional cytotoxic agents have become the new standard of care for extensive-stage small cell lung cancer (SCLC).
Soh Mee Park, Jonghyun Jeong, Yu Jung Kim, Ju-Yeun Lee   +3 more
doaj   +1 more source

Euglycemic Diabetic Ketoacidosis Mimicking an Acute Asthma Exacerbation in a Young Adult With New‐Onset Diabetes: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Euglycemic diabetic ketoacidosis can mimic acute asthma, including in previously undiagnosed diabetes and without SGLT‐2 inhibitor use. Carbohydrate restriction may precipitate life‐threatening ketoacidosis, particularly with insulin deficiency.
Faizan E Mustafa, Sarim Hassan Shahab, Basit Ali, Aleena Majeed, Fazal Habib, Muhammad Sajjad   +5 more
wiley   +1 more source

Chlorantraniliprole Formulation Poisoning: A Signal for Cardiac Conduction Abnormalities

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Chlorantraniliprole poisoning is rarely reported in humans. A 25‐year‐old man developed sinus bradycardia and first‐degree atrioventricular block after ingesting a chlorantraniliprole 18.5% suspension concentrate formulation. Laboratory investigations were unremarkable, and ECG abnormalities resolved within 72 h with supportive care.
Prashim Sharma, Nishan Subedi, Kanchan Thulung Rai, Alisha Adhikari   +3 more
wiley   +1 more source

Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT3 receptor antagonists [PDF]

, 2010
J. A. Rudd, N. Percie du Sert, P. L. R. Andrews, C. C. Apfel, Andrews, PL, Percie du Sert, N, Rudd, JA, Apfel, CC   +7 more
core   +1 more source

Burkitt Lymphoma Presenting as Renal Failure: Learning From Diagnostic Pitfalls in Pediatrics

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This case highlights that pediatric Burkitt lymphoma may present without classic systemic manifestations, instead presenting as acute renal failure secondary to peritoneal lymphomatosis. Prompt recognition of rapid progression, hyperuricemia, and obstructive uropathy, especially with initially normal blood counts, is essential to minimize ...
Anne Boldt, Khanh Mai, Adriana Dhawan, Lucie M. Turcotte, Robin Williams, Aarti Kamat   +5 more
wiley   +1 more source

Acute Hemorrhagic Manifestations in a Pregnant Patient With Type 1 von Willebrand Disease: Challenges in Management of Bleeding Disorders During Gestation

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT This case reports a primigravida with Type 1 von Willebrand disease experiencing hematuria and gingival bleeding despite prophylaxis. Although pregnancy raises factor levels, her response was insufficient. Desmopressin successfully controlled mucosal hemorrhage, avoiding antifibrinolytics due to obstructive risk.
Jose Luis Rojas‐Oviedo, María Fernanda Leal Walteros, Dauris Lineth Mejía Pérez, Jorge Eliecer Castellanos Corredor, Danna Geraldinne Amaya Sánchez, Ana Sofía Lancheros Ramírez   +5 more
wiley   +1 more source

Retrospective Analysis of Zolbetuximab‐Associated Hypoalbuminemia in Claudin 18.2‐Positive Advanced Gastric Cancer

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Hypoalbuminemia has been recognized as a characteristic adverse event associated with zolbetuximab plus chemotherapy in the treatment of claudin 18.2‐positive advanced gastric cancer. However, its incidence, clinical predictors, and management in real‐world settings remain unclear.
Taro Mizuno, Yukiya Narita, Taiju Ando, Yasunobu Ishizuka, Sho Umegaki, Kazunori Honda, Toshiki Masuishi, Hiroya Taniguchi, Shigenori Kadowaki, Masashi Ando, Masahiro Tajika, Kei Muro   +11 more
wiley   +1 more source