Results 131 to 140 of about 21,842 (260)
Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?
Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley +1 more source
ABSTRACT Drug‐induced liver injury remains a severe but underdiscussed adverse effect of nitrofurantoin. This case uniquely describes hepatic injury occurring after four doses of nitrofurantoin, with a disproportionate rise in AST and rapid complete recovery following discontinuation of the drug. A RUCAM score of six supports the probability of DILI.
Mahir H. Sampat
wiley +1 more source
Segmental Hair Analysis of Diphenhydramine and Cyclizine Following a Single Dose
A single oral dose of diphenhydramine and cyclizine can be quantified in human head hair for a minimum of 5 months and, in certain cases, for up to 1 year following intake. Among 12 study participants, the measured concentrations ranged from 0 to 610 pg/mg within 1 year post‐intake.
Jan Bílek +3 more
wiley +1 more source
Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT3 receptor antagonists [PDF]
J. A. Rudd +7 more
core +1 more source
The glucagon stimulation test demonstrates a favourable safety profile in adults with chronic moderate‐to‐severe traumatic brain injury, with transient, non‐severe adverse effects and no serious complications. ABSTRACT Introduction Growth hormone deficiency (GHD) is a common and clinically significant consequence of moderate‐to‐severe traumatic brain ...
Corey Snyder +2 more
wiley +1 more source
ABSTRACT Background Elective pediatric upper airway procedures are generally safe; however, some patients require unplanned pediatric intensive care unit admission, increasing care complexity. Aims To identify perioperative risk factors associated with unplanned pediatric intensive care unit admission following elective pediatric upper airway surgery ...
Hayes Stancliff +5 more
wiley +1 more source
Radiographic remission of a presumptive unresectable haemangiosarcoma treated with toceranib, piroxicam, and propranolol. In a dog with ACVIM Stage B2 myxomatous mitral valve disease where doxorubicin‐based chemotherapy was contraindicated, this multimodal regimen achieved marked tumour reduction and radiographic disappearance.
Woo Dae Park
wiley +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley +2 more sources
Optimizing antiemetic therapy in multiple-day and multiple cycles of chemotherapy
PURPOSE OF REVIEW: Only a few studies have investigated the effect of antiemetic therapy in patients treated with multiple-day or multiple cycles of chemotherapy.
Ellebaek, E., Herrstedt, J.
core
ABSTRACT Introduction Same‐day discharge after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA) is increasing, but the optimal anaesthetic technique for outpatient pathways remains uncertain. Neuraxial anaesthesia is widely recommended based on observational evidence, whereas fast‐track programmes using short‐acting total ...
Erik Noppa +6 more
wiley +1 more source

