Results 161 to 170 of about 19,524 (248)

Paraquat Poisoning: A Case of Daisley–Barton Syndrome and Hepatorenal Failure

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Paraquat (PQ) is a highly toxic herbicide that causes severe poisoning. It mainly affects the lungs, liver, and kidneys. When ingested intentionally, it has a high mortality rate due to the absence of an effective antidote. We present a rare case of a 35‐year‐old female with deliberate ingestion of paraquat for a suicide attempt.
Ali Gohar   +8 more
wiley   +1 more source

Saliva as a TDM Matrix and Its Application in the Model‐Informed Precision Dosing

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 12, Page 1650-1660, December 2025.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu   +9 more
wiley   +1 more source

Paroxysmal Nocturnal Hemoglobinuria in Pregnancy Treated With Pegcetacoplan: Case Report and Pharmacokinetic Analysis

open access: yeseJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT There is an unmet clinical need for effective treatment of paroxysmal nocturnal hemoglobinuria (PNH) in pregnancy for patients with inadequate response to C5 inhibitors. We report the first case of pegcetacoplan use in pregnancy with accompanying pharmacokinetic analysis.
Benjamin Chin‐Yee   +9 more
wiley   +1 more source

Alpinia galanga Rhizome Extract Shields Against Noise‐Induced Cardiotoxicity via Antioxidant and Anti‐Inflammatory Actions: Experimental Insights

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 24, December 2025.
Alpinia galanga rhizome extract (GRE) was analyzed in vitro to identify its bioactive compounds, tested in vivo in a Wistar rat model of noise‐induced cardiotoxicity, and validated in silico by molecular docking. The combined results highlight the cardioprotective potential of GRE.
Takoua Ben Attia   +9 more
wiley   +1 more source

Chemotherapy-Induced Nausea and Vomiting: The Role of Aprepitant

open access: yesMiddle East Journal of Cancer, 2011
Antiemetics are given to cancer patients prior to their chemotherapy sessions to protect them from nausea and vomiting induced by chemotherapy. The responsible health care team member will choose the type of antiemetic required to prevent the patient ...
Muath Mohammed Abu Hilal
doaj  

A Novel Approach of Nanosponges Capsules of an Antiemetic Drug

open access: hybrid, 2022
Bendi Sri Venkateswarlu   +3 more
openalex   +1 more source

Drink lemonade! Implementation of drinking 2 h before elective orthopedic surgery to reduce prolonged fasting

open access: yesNutrition in Clinical Practice, Volume 40, Issue 6, Page 1538-1551, December 2025.
Abstract Background Prolonged fasting before surgery remains common despite guidelines recommending liquid fasting for 2 h and solid fasting for 6 h preoperatively. Consuming carbohydrate‐rich drinks until 2 h before surgery improves patient well‐being and reduces postoperative complications and insulin resistance.
Ingrid M. S. Heijnen   +5 more
wiley   +1 more source

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