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Current Opinion in Anaesthesiology, 2002
Numerous studies about postoperative nausea and vomiting management are available and meta-analyses have helped to define the appropriate doses of the effective drugs. Almost all recent papers include some economical considerations. In order to rationalize the therapeutic protocols, strategies including systematic prophylaxis, treatment of established ...
Anne-Marie Diemunsch, Pierre Diemunsch
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Numerous studies about postoperative nausea and vomiting management are available and meta-analyses have helped to define the appropriate doses of the effective drugs. Almost all recent papers include some economical considerations. In order to rationalize the therapeutic protocols, strategies including systematic prophylaxis, treatment of established ...
Anne-Marie Diemunsch, Pierre Diemunsch
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Critical Reviews in Oncology/Hematology, 2002
The emetogenic potential of cancer chemotherapeutic agents varies according to the agent employed. Among the highly emetogenic agents, cisplatin has been the most studied. As for emesis induced by cisplatin, an optimal antiemetic schedule is effective in 70-90% of cases of acute emesis, in 60% of cases of delayed emesis, whereas acute emesis induced by
L. Licitra, S. Spinazzé, F. Roila
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The emetogenic potential of cancer chemotherapeutic agents varies according to the agent employed. Among the highly emetogenic agents, cisplatin has been the most studied. As for emesis induced by cisplatin, an optimal antiemetic schedule is effective in 70-90% of cases of acute emesis, in 60% of cases of delayed emesis, whereas acute emesis induced by
L. Licitra, S. Spinazzé, F. Roila
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Metoclopramide as an Antiemetic
Annals of Internal Medicine, 1981Excerpt To the editor: We read with interest the review by Seigel and Longo (1) on the control of chemotherapy-induced emesis.
Jonathan E. McDermed, Stephen B. Strum
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Methodology of Antiemetic Trials [PDF]
Drugs, 1992 Progress in antiemetic research dictates that clinical trials of antiemetic agents be conducted according to guidelines for Good Clinical Practice, as follows. Studies must be of a prospective, parallel-group design in which the new treatment is compared with the existing best available treatment, after optimal dosage schedules for each have been ...
J. Gordon McVie, Karel M. de Bruijn
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Current Opinion in Oncology, 1997
In the past few years a combination of a 5-HT3 receptor antagonist plus dexamethasone has been shown to be the most efficacious antiemetic prophylaxis of acute emesis induced by cisplatin and moderately emetogenic chemotherapy. In the prevention of cisplatin-induced delayed emesis oral metoclopramide or ondansetron, both combined with dexamethasone ...
F, Roila, A, Del Favero
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In the past few years a combination of a 5-HT3 receptor antagonist plus dexamethasone has been shown to be the most efficacious antiemetic prophylaxis of acute emesis induced by cisplatin and moderately emetogenic chemotherapy. In the prevention of cisplatin-induced delayed emesis oral metoclopramide or ondansetron, both combined with dexamethasone ...
F, Roila, A, Del Favero
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Gastroenterology Clinics of North America, 1992
This article explores recent knowledge on the physiology and neuropharmacology of the emetic process. It seeks to outline the indications for specific antiemetic drugs and where their actions are targeted. Much of the information for the role of antiemetic drugs has come from experience with antiemetics in patients receiving cytotoxic chemotherapy. The
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This article explores recent knowledge on the physiology and neuropharmacology of the emetic process. It seeks to outline the indications for specific antiemetic drugs and where their actions are targeted. Much of the information for the role of antiemetic drugs has come from experience with antiemetics in patients receiving cytotoxic chemotherapy. The
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International Anesthesiology Clinics, 1994
In an editorial, Kapur [4] described perioperative nausea and vomiting as the big "little problem following ambulatory surgery." In contrast to the attitudes of some physicians, patients put a high value on freedom from nausea and emesis in the postoperative period and are willing to accept some pain and drowsiness as the cost of controlling PONV [85].
Paul F. White, Mehernoor F. Watcha
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In an editorial, Kapur [4] described perioperative nausea and vomiting as the big "little problem following ambulatory surgery." In contrast to the attitudes of some physicians, patients put a high value on freedom from nausea and emesis in the postoperative period and are willing to accept some pain and drowsiness as the cost of controlling PONV [85].
Paul F. White, Mehernoor F. Watcha
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Current Opinion in Oncology, 1992
Despite major progress in the treatment of chemotherapy-induced emesis, nearly one third of patients undergoing cisplatin-based regimens still experience emesis within the first 24 hours of chemotherapy. An adequate treatment of delayed and anticipatory emesis remains to be determined.
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Despite major progress in the treatment of chemotherapy-induced emesis, nearly one third of patients undergoing cisplatin-based regimens still experience emesis within the first 24 hours of chemotherapy. An adequate treatment of delayed and anticipatory emesis remains to be determined.
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