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Antiemetics, Akathisia, and Pregnancy
Psychosomatics, 2007Gastrointestinal disorders are common in pregnant women. These disorders are often treated with antiemetic medications that block central dopaminergic neurotransmission. Dopamine antagonists can cause akathisia. Hormonal changes and other factors may place pregnant women at increased risk for the development of severe antiemetic-induced akathisia.
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Myths of antiemetic administration
Cancer Nursing, 1989Chemotherapy as a treatment modality for cancer has dramatically improved outcomes for patients. However, to attain therapeutic benefit, side effects and toxicities must be endured. Among the most frequent and distressing side effects are nausea and vomiting. The experience of nausea and vomiting may become so devastating that patients will discontinue
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The latest consensus on antiemetics
Current Opinion in Oncology, 2018Purpose of review The present review summarizes and discuss the most recent updated antiemetic consensus. Recent findings Two new neurokinin (NK)1-receptor antagonists, netupitant and rolapitant, have been approved by the Food and Drug Administration and the European Medicines ...
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Antiemetics in Cancer Chemotherapy
1985Nausea and vomiting induced by several cancer chemotherapy agents is often the most distressing side effect of treatment. The mechanisms are quite complex. The vomiting center in the reticular formation can be stimulated by either afferent Stimuli from the gastrointestinal tract or by the chemoreceptor trigger zone (CTZ).
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Canadian Journal of Physiology and Pharmacology, 1990
Three major areas of medicine are identified in which there is a need for new antiemetic drugs. These are the nausea and vomiting arising from gastrointestinal motility disturbances (functional dyspepsia, diabetic neuropathy, classical migraine), the sickness evoked by abnormal motion, and the severe emesis experienced by cancer patients as a result ...
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Three major areas of medicine are identified in which there is a need for new antiemetic drugs. These are the nausea and vomiting arising from gastrointestinal motility disturbances (functional dyspepsia, diabetic neuropathy, classical migraine), the sickness evoked by abnormal motion, and the severe emesis experienced by cancer patients as a result ...
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Reports of Anaphylaxis with an Antiemetic
AJN, American Journal of Nursing, 2018The labeling for rolapitant (Varubi), an antiemetic used with chemotherapy, will now include a safety warning stating that the drug can cause anaphylaxis and serious hypersensitivity reactions.Nurses should assess patients for hypersensitivity to any of the drug's components prior to administration.
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