Results 61 to 70 of about 36,025 (301)

The impact of 5-hydroxytryptamine-receptor antagonists on chemotherapy treatment adherence, treatment delay, and nausea and vomiting. [PDF]

open access: yes, 2015
PurposeTo determine the incidence of chemotherapy-induced nausea/vomiting (CINV) and chemotherapy treatment delay and adherence among patients receiving palonosetron versus other 5-hydroxytryptamine receptor antagonist (5-HT3 RA) antiemetics.Materials ...
Grabner, Michael   +3 more
core   +2 more sources

Impact of Combined Additional Resections on the Surgical Outcomes of Robot‐Assisted Resection of Thymic Epithelial Tumors

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Robot‐assisted thoracoscopy (RATS) is rapidly emerging as the preferred approach for the resection of thymic epithelial tumors (TET). Current challenges include the role of RATS in locally advanced disease and combined additional resections.
Benedikt Niedermaier   +12 more
wiley   +1 more source

Overnight Monitoring After T&A for Children Ages 24–36 Months: Is It Always Necessary?

open access: yesThe Laryngoscope, EarlyView.
This study aims to identify whether all children < 3 years of age require overnight admission after tonsillectomy with or without adenoidectomy. We found that 98.7% of children who were off oxygen within 3 h after surgery never went back on oxygen during the entire monitoring period.
Tyler Van Heest   +4 more
wiley   +1 more source

New antiemetic drugs

open access: yesAnnals of Oncology, 2006
Important progress in the prophylaxis of chemotherapy-induced acute and delayed emesis has been achieved but some fundamental needs still remain that requires new, efficacious antiemetic drugs.A critical review of the results of published studies of aprepitant, a new NK1 receptor antagonist, and of palonosetron, a 5-HT3 receptor antagonist with a ...
F, Roila, S, Fatigoni
openaire   +2 more sources

Targeting tachykinin receptors in neuroblastoma [PDF]

open access: yes, 2016
Neuroblastoma is the most common extracranial tumor in children. Despite aggressive multimodal treatment, high-risk neuroblastoma remains a clinical challenge with survival rates below 50%.
Althoff, Kristina   +14 more
core   +3 more sources

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

open access: yesChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz   +10 more
wiley   +1 more source

An assessment of chemotherapy-induced nausea and vomiting direct costs in three EU countries

open access: yesDrugs in Context, 2015
Background: Chemotherapy-induced nausea and vomiting (CINV) has been commonly reported as one of the most distressing adverse effects among treated patients with cancer.
Marco Turini   +4 more
doaj   +1 more source

Effect of Testosterone Therapy on Cytochrome P450 3A and P‐Glycoprotein Activities Using Midazolam and Digoxin as Probe Substrates Among Transgender Adults

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
ABSTRACT Background Gender‐affirming testosterone therapy is one part of the standard of care for more than 1 million transgender adults in the United States. Testosterone therapy may influence the activities of drug‐metabolizing enzymes and transporters, but knowledge about its effect on the pharmacokinetics of other medications is limited.
Michiko Hunter   +9 more
wiley   +1 more source

The pharmacological basis of Cuscuta reflexa whole plant as an antiemetic agent in pigeons

open access: yesToxicology Reports, 2020
Cuscuta reflexa has been traditionally used as an antiemetic. Additionally, it has been used in various herbal formulations for the treatment of emesis. So far, there is no scientific evidence of the plant extract as antiemetic. Therefore, this study was
Naveed Muhammad   +10 more
doaj   +1 more source

Update on medication-overuse headache and its treatment [PDF]

open access: yes, 2015
OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA   +2 more
core   +1 more source

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