Results 71 to 80 of about 35,117 (307)

One‐Pot Synthesis of Novel β‐Carboline‐{α‐Acylaminoamide}‐Bisindole Derivatives: Antibacterial Evaluation, Molecular Docking, and Density Functional Theory Studies

ChemistryOpen, EarlyView.
A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) employing an atom‐economical one‐pot Ugi four‐component reaction and their antibacterial testing alongside docking studies, is reported. A new series of β‐carboline‐{α‐acylaminoamide}‐bisindole hybrids (12a–l) is designed and synthesized employing an atom‐economical one‐pot Ugi ...
Ankit Kumar Atri, Lavanya Khullar, Gobind Kumar, Sahil Mishra, Tamanna Dua, Vinay Singh, Kusum Harjai, Parvesh Singh, Vasundhara Singh   +8 more
wiley   +1 more source

Characterizing Difficulty and Life Disruption During B‐Acute Lymphoblastic Leukemia Therapy From the Perspective of Parents: A Survey Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Children with B‐acute lymphoblastic leukemia (B‐ALL) treated in resource‐intensive settings have a high likelihood of cure, but therapy is long, burdensome, and associated with substantial toxicities. Understanding parents’ perceptions of the most disruptive and difficult aspects of B‐ALL treatment is critical to future improvements in
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory J. Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

Retrospective analysis of real‐world prescribing data for managing cisplatin‐based chemotherapy‐induced nausea and vomiting in China

Cancer Medicine
Background The current utilization of neurokinin‐1 receptor antagonists (NK1RAs) and the impact of updated guidelines on prescription patterns of antiemetic drugs among Chinese patients receiving highly emetogenic chemotherapy (HEC) remain undetermined ...
Xia Si, Hongyan Zhang, Qingming Ding, Gang Liu, Lin Huang, Xin Sun   +5 more
doaj   +1 more source

Modulatory effects of phytol on the antiemetic property of domperidone, possibly through the D2 receptor interaction pathway: in vivo and in silico studies

3 Biotech, 2023
Md. Shimul Bhuia, Tawhida Islam, Md. Rokonuzzman, Abdullah Al Shamsh Prottay, Fatama Akter, Md Imran Hossain, R. Chowdhury, Md. Azim Kazi, A. B. R. Khalipha, H. Coutinho, M. T. Islam   +10 more
semanticscholar   +1 more source

A Review of NEPA, a Novel Fixed Antiemetic Combination with the Potential for Enhancing Guideline Adherence and Improving Control of Chemotherapy-Induced Nausea and Vomiting

BioMed Research International, 2015
Combination antiemetic regimens targeting multiple molecular pathways associated with emesis have become the standard of care for prevention of chemotherapy-induced nausea and vomiting (CINV) related to highly and moderately emetogenic chemotherapies ...
P. Hesketh, M. Aapro, K. Jordan, L. Schwartzberg, S. Bošnjak, H. Rugo   +5 more
semanticscholar   +1 more source

European Consensus on Functional Bloating and Abdominal Distension—An ESNM/UEG Recommendations for Clinical Management

United European Gastroenterology Journal, EarlyView.
ABSTRACT Introduction Abdominal distension is an objective visible sign of increased abdominal girth. Bloating is a feeling of abdominal fullness and discomfort. Bloating may be associated or not with abdominal distension. Bloating and abdominal distension are among the most commonly reported gastrointestinal symptoms and may be associated with both ...
Chloé Melchior, Heinz Hammer, Serhat Bor, Elizabeth Barba, Indira Benjak Horvat, Altay Celebi, Vasile Drug, Dan Dumitrascu, Ismail Hakki Kalkan, Goran Hauser, Christos Lionis, Dan Livovsky, Amir Mari, Agata Mulak, Teodora Surdea‐Blaga, Jan Tack, Tim Vanuytsel, Edoardo Vincenzo Savarino, Natalia Zarate‐Lopez, Johann Hammer, Ram Dickman   +20 more
wiley   +1 more source

Perineural Invasion in Pancreatic Ductal Adenocarcinoma: Recapitulating Its Importance and Defining Future Directions

United European Gastroenterology Journal, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, mainly due to its aggressive nature, early metastasis, diagnosis at late stages, and limited response to systemic anticancer therapy. Perineural invasion (PNI), defined as the infiltration of neoplastic cells along nerve fibers and within nerve sheaths, is ...
Martin Lovecek, Esra Dirimtekin, Ingrid Garajová, Giulia Gasparini, Stefano Crippa, Elisa Giovannetti, Dana Sochorova, Carmen Mota Reyes, Ihsan Ekin Demir, Pinar Uysal‐Onganer, on behalf TRANSPAN PNI Group   +10 more
wiley   +1 more source

Resolution of a persistent pneumothorax by blood patch pleurodesis in a cat (Felis catus) with primary pulmonary lymphoma

Veterinary Record Case Reports, EarlyView.
Abstract An 18‐year‐old, spayed, female, domestic shorthair cat was presented to our hospital with acute dyspnoea following an episode of vomiting. Thoracic radiography revealed a severe pneumothorax. Despite multiple thoracocenteses, the pneumothorax persisted. Under general anaesthesia, computed tomography revealed multiple pulmonary masses.
Yuki Hoshino, Reina Fujiwara, Masaaki Katayama, Kohei Nakata, Takahiro Nagumo, Yumiko Kagawa   +5 more
wiley   +1 more source

PROPHYLACTIC ANTIEMETIC THERAPY WITH ONDANSETRON, DEXAMETHASONE AND COMBINED ONDANSETRON AND DEXAMETHASONE IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY UNDER GENERAL ANAESTHESIA (GA)

Journal of University Medical & Dental College, 2017
: OBJECTIVE: The aim of this study was to find a better prophylaxis against postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic cholecystectomy. STUDY DESIGN: A randomized control study was carried out for comparison.
Nadia Bano, Nazim Hayat, A.G Rehan
doaj  

Efficacy Of Ondansetron, Granisetron And Palonosetron On Post operative Nausea and Vomiting in Patients undergoing Elective Neurosurgical Procedure

Basrah Journal of Surgery
Background Neurosurgery is associated with high incidence of PONV. 5HT3 Antagonists are highly specific for the treatment of nausea and vomiting. They are preferred antiemetic agents in neurosurgeries due to the lack of sedation and extrapyramidal ...
Vasudha Govil, Richa Malik , Prashant Kummar, Anju Rani , Sudha Puhal   +4 more
doaj   +1 more source