Results 91 to 100 of about 38,812 (326)
BACKGROUND Chemotherapy-induced nausea and vomiting (CINV) is a debilitating side effect. Previous studies have primarily focused on prophylactic therapy, but no published reports have evaluated the treatment of breakthrough CINV. METHODS A prospective,
Jason M. Jones+5 more
semanticscholar +1 more source
Plain Language Summary: This randomized trial was designed to test the effectiveness and safety of rimegepant for the acute treatment of migraine among adults in Japan. Results indicated that rimegepant was more effective than placebo, and the 75 mg dose was observed to be more effective than the 25 mg dose.
Koichi Ikeda+11 more
wiley +1 more source
The antiemetic action of propofol [PDF]
SummaryEighty patients who underwent minor gynaecological surgery were anaesthetised with either incremental propofol or incremental methohexitone after an opioid premedication. The group anaesthetised with propofol had significantly fewer emetic sequelae and the results suggest that propofol has a definite antiemetic action.
J. S. C. McCollum+2 more
openaire +3 more sources
Plain Language Summary: This study tested the effectiveness of rimegepant for migraine prevention in Japan. Results showed that rimegepant was more effective than placebo in reducing monthly migraine days, with very few adverse effects. These results support the previous findings from a clinical study conducted in the United States and broaden them to ...
Shigekazu Kitamura+11 more
wiley +1 more source
Abstract Objective To assess the safety, tolerability, and treatment effects of rimegepant 75 mg every other calendar day (EOD) for the preventive treatment of migraine in a 52‐week, open‐label extension (OLE) study. Background Rimegepant is an oral small molecule calcitonin gene–related peptide receptor antagonist approved for the acute treatment of ...
David Kudrow+3 more
wiley +1 more source
The incidences of nausea and vomiting after general anesthesia with remimazolam versus sevoflurane: a prospective randomized controlled trial [PDF]
Background Postoperative nausea and vomiting (PONV) refers to nausea and vomiting that occurs within 24-h after surgery or in the post-anesthesia care unit (PACU).
Yeong Min Yoo+4 more
doaj +1 more source
Synergistic drug combinations from electronic health records and gene expression. [PDF]
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William+19 more
core +2 more sources
Use of antiemetics in children with acute gastroenteritis: Are they safe and effective?
The use of antiemetics is a controversial topic in treatment of pediatric gastroenteritis. Although not recommended by the American Academy of Pediatrics, antiemetics are commonly prescribed by physicians. A review of the literature shows side effects of
J. Manteuffel
semanticscholar +1 more source
Abstract Background Patients with disorders of gut‐brain interaction (DGBIs) presenting to specialist care have a high prevalence of psychiatric morbidity. Psychiatrists can provide effective treatments for these disorders; however, care is rarely delivered in an integrated manner. Aims This study aimed to characterise patients seen by psychiatrists in
Evangelia Dendrinos+8 more
wiley +1 more source
Role of ganaton in antiemetic therapy. New treatment capacities
The practical introduction of new effective drugs for the prevention and treatment of nausea and vomiting is one of the important constitu- ents of maintenance therapy in cancer patients, which helps maintain a good quality of life during drug treatment.
A. V. Snegovoy, L. V. Manzyuk
doaj +1 more source