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Methodology of trials with antiemetics
Supportive Care in Cancer, 1996Chemotherapy-induced nausea and vomiting can today be controlled with the "new" antiemetics or with their various combinations in a high percentage of patients. Despite this, for some subgroups of patients, certain chemotherapy regimens and some aspects of the phenomenon (delayed presentation), emesis remains a critical problem.
Enzo Ballatori +3 more
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MASCC antiemetics in advanced cancer updated guideline
Supportive Care in Cancer, 2021Mellar Davis +7 more
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Efficacy and safety of antiemetics
Cancer Treatment Reviews, 1994Of all the adverse effects associated with cancer chemotherapy, patients find nausea and vomiting the most distressing (I, 2). Indeed, nausea and vomiting continue to be critical problems in cancer chemotherapy. They can lead to a dramatic deterioration of the patients’ quality of life and result in up to 50% of patients delaying or missing treatment ...
Michel Marty, Volker Diehl
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Antiemetics, Akathisia, and Pregnancy
Psychosomatics, 2007Gastrointestinal disorders are common in pregnant women. These disorders are often treated with antiemetic medications that block central dopaminergic neurotransmission. Dopamine antagonists can cause akathisia. Hormonal changes and other factors may place pregnant women at increased risk for the development of severe antiemetic-induced akathisia.
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Myths of antiemetic administration
Cancer Nursing, 1989Chemotherapy as a treatment modality for cancer has dramatically improved outcomes for patients. However, to attain therapeutic benefit, side effects and toxicities must be endured. Among the most frequent and distressing side effects are nausea and vomiting. The experience of nausea and vomiting may become so devastating that patients will discontinue
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Antiemetics in Cancer Chemotherapy
1985Nausea and vomiting induced by several cancer chemotherapy agents is often the most distressing side effect of treatment. The mechanisms are quite complex. The vomiting center in the reticular formation can be stimulated by either afferent Stimuli from the gastrointestinal tract or by the chemoreceptor trigger zone (CTZ).
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Canadian Journal of Physiology and Pharmacology, 1990
Three major areas of medicine are identified in which there is a need for new antiemetic drugs. These are the nausea and vomiting arising from gastrointestinal motility disturbances (functional dyspepsia, diabetic neuropathy, classical migraine), the sickness evoked by abnormal motion, and the severe emesis experienced by cancer patients as a result ...
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Three major areas of medicine are identified in which there is a need for new antiemetic drugs. These are the nausea and vomiting arising from gastrointestinal motility disturbances (functional dyspepsia, diabetic neuropathy, classical migraine), the sickness evoked by abnormal motion, and the severe emesis experienced by cancer patients as a result ...
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Antiemetics: American Society of Clinical Oncology Focused Guideline Update.
Journal of oncology practice / American Society of Clinical Oncology, 2016P. Hesketh, Kari Bohlke, M. Kris
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Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update.
Journal of Clinical Oncology, 2017P. Hesketh +16 more
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