Results 101 to 110 of about 3,394 (285)

DNA Nanostructure‐Templated Multivalency Enables Broad‐Spectrum Virus Inhibition

Advanced Science, EarlyView.
A honeycomb‐shaped DNA nanostructure is introduced that organizes nanobodies or aptamers into trimeric clusters mirroring the native hemagglutinin arrangement on influenza viruses. This geometry‐matched multivalency enhances binding avidity by up to 1000‐fold, resulting in robust, broad‐spectrum viral neutralization and a 30–55% improvement in host ...
Saurabh Umrao, Abhisek Dwivedy, Dhanush Gandavadi, Chi Chen, Lifeng Zhou, Jinwei Duan, Vineetha Mareddy, Ying Fang, Xing Wang   +8 more
wiley   +1 more source

A Review: Momordica charantia L.'s Biological Active Components and Its Potential Use in Traditional Therapies

International Journal of Traditional and Complementary Medicine Research, 2020
The use of herbs for therapeutic purposes has been widespread since ancient times. In traditional treatments, plants are applied in a variety of forms, either directly or prepared by isolation and / or enrichment of biologically active ingredients ...
Gülşah Aydın, Ertuğrul Kaya
doaj  

Determination of possible contraceptive potential of methanolic leaf extract of Mentha longifolia L. in adult male rats: a biochemical and histological study. [PDF]

Toxicol Res (Camb), 2022
David M, Ain QU, Jahan S, Ahmad M, Shah Q, Afsar T, Shafique H, Alanezi TN, Almajwal A, Ijaz U, Razak S.   +10 more
europepmc   +1 more source

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

Synthesis of 2-Substituted-phenyl-3-aroyl-4-oxo-4 H-1 ,3- benzoxazines as Possible Antifertility/CNS Active Agents

, 1985
Y. D. KULKARNI, S. H. R. ABDI, V. L. SHARMA, P. R. DUA, G. SHANKER   +4 more
openalex   +1 more source

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

Advanced Science, EarlyView.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin, Koji Nagaoka, Myrofora Panagi, Akihiro Hosoi, Fotios Mpkeris, Pengwen Chen, Thahomina T. Khan, Margaret R. Martin, Changbo Sun, Chrysovalantis Voutouri, Maria Louca, Panagiotis Papageorgis, Akira Sumiyoshi, Nobuhiro Nitta, Kazuyoshi Takeda, Ichio Aoki, Kazunori Kataoka, Triantafyllos Stylianopoulos, Kazuhiro Kakimi, Horacio Cabral   +19 more
wiley   +1 more source

A COMPARISON OF THE ANTIFERTILITY EFFECTS OF ALKYLATING AGENTS AND VINCA ALKALOIDS IN MALE RATS [PDF]

, 1978
Robin A. Cooke, A. Nikles, H. P. Roeser
openalex   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source

Fertility regulatory potential of Persicaria hydropiper (L.) Delarbre methanolic root extract in female albino mice: An insight into the phytochemicals present and role of the extract in contraception. [PDF]

Saudi Pharm J, 2022
Bairagi J, Saikia PJ, Boro F, Hazarika A.   +3 more
europepmc   +1 more source

Synthesis of Possible Antifertility Compounds : Part II. Synthesis of Bis-dichloroacetyl Derivatives of some Acid Hydrazides

, 1967
S S. Tiwari, Savitri Srivastava
openalex   +1 more source