Results 121 to 130 of about 3,524,198 (392)

Magnetic Resonance Imaging‐Based Quantification of Endosomal Escape Using Iron Oxide Nanoparticle‐Loaded Lipid Nanoparticles

Advanced Healthcare Materials, EarlyView.
The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee, Jeongbin Park, Han Na Jung, Shengjun Li, Zhijun Lin, Hyung‐Jun Im   +5 more
wiley   +1 more source

Antifungal agents: Polyene, azole, antimetabolite, other and future agents

Journal of Basic Research in Medical Sciences, 2018
Antifungals have always been considered as one of the astonishing discoveries of the 20th century. This is correct, but the real marvel is the development of antifungal resistance in hospitals, communities, and the environment concomitant with their use.
Fardin Ali Malayeri, Aliakbar Rezaei, Omid Raiesi   +2 more
doaj  

Influence of subinhibitory antifungal concentrations on extracellular hydrolases and biofilm production by Candida albicans recovered from Egyptian patients

BMC Infectious Diseases, 2019
Background Extracellular hydrolases (phospholipase, aspartyl protease and haemolysin) and biofilm production are considered as major virulence factors of the opportunistic pathogenic fungus Candida albicans.
Houdaii H. El-Houssaini, Omnia M. Elnabawy, Hebatallah A. Nasser, Walid F. Elkhatib   +3 more
doaj   +1 more source

Synergism between fungal enzymes and bacterial antibiotics may enhance biocontrol [PDF]

, 2002
The interactions between biocontrol fungi and bacteria may play a key role in the natural process of biocontrol, although the molecular mechanisms involved are still largely unknown.
FOGLIANO, VINCENZO, LORITO, MATTEO, SCALA, FELICE, WOO, SHERIDAN LOIS   +3 more
core   +1 more source

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, EarlyView.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

MEDICINAL PLANTS AND BIOLOGICALLY ACTIVE SUBSTANCES WITH ANTIFUNGAL PROPERTIES

Фундаментальная и клиническая медицина, 2017
Fungal diseases, caused by pathogenic fungi from air, soil, water, plants, and even the human body, are dangerous for humans of all age groups. Currently, commercially available antifungal agents mainly include synthetic products having numerous ...
ANDREY A. Mar‘In, NATALIA E. Kolomiets
doaj  

Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives [PDF]

, 2010
A simple and efficient method has been developed for the synthesis of various 2-quinoxalinone-3-hydrazone derivatives using microwave irradiation technique. The series of 2-quinoxalinone-3-hydrazone derivatives synthesized, were structurally confirmed by
Ajani, Olayinka O.
core   +1 more source

Transparent Multifunctional Wearable Strain Sensor With Self‐Healing and Antibacterial Capabilities for Human Motion Detection

Advanced Healthcare Materials, EarlyView.
A transparent dual‐network strain sensor integrates robust mechanical properties, room‐temperature self‐healing, and stable performance under sub‐zero conditions and prolonged storage. Its excellent biocompatibility and antimicrobial properties enable safe skin contact.
Wenqing Chen, Wei Huang, Rohit Gupta, Abbas Heydari, Biswajoy Bagchi, Lulu Xu, Yang Xue, Eirini Velliou, Manish K Tiwari   +8 more
wiley   +1 more source

Antifungal activity of redox-active benzaldehydes that target cellular antioxidation

Annals of Clinical Microbiology and Antimicrobials, 2011
Background Disruption of cellular antioxidation systems should be an effective method for control of fungal pathogens. Such disruption can be achieved with redox-active compounds.
Mahoney Noreen, Chan Kathleen L, Kim Jong H, Campbell Bruce C   +3 more
doaj   +1 more source

The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]

, 2017
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K, Diaz, Jose J, Jr, Huston, Jared M, May, Addison K, Mazuski, John E, Mollen, Kevin P, Nadler, Evan P, O\u27Neill, Patrick J, Prince, Jose M, Rosengart, Matthew R, Sawyer, Robert G, Tessier, Jeffrey M   +11 more
core   +3 more sources