Results 351 to 360 of about 3,492,596 (401)
Journal of the American Academy of Dermatology, 1995 Some of the next articles are maybe not open access.
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Recent Progress in the Discovery of Antifungal Agents Targeting the Cell Wall.
Journal of Medicinal Chemistry, 2020Due to the limit of available treatments and the emergence of drug resistance in clinic, invasive fungal infections are an intractable problem with high morbidity and mortality.
Wei Liu, Lin Yuan, Shengzheng Wang
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Antifungal agents, WO2009025733
Expert Opinion on Therapeutic Patents, 2009The incidence and prevalence of serious mycoses continues to be a public health problem. These infections are an important cause of morbidity and mortality, especially in immunocompromised patients. The present patent deals with isolation and characterization of a 'pure' mixture of two novel isoxazolidinone-containing natural products from two new ...
Deshpande Sunita Ranjan +2 more
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Plant-Derived Products as Antibacterial and Antifungal Agents in Human Health Care.
Current Medicinal Chemistry, 2019A number of papers reporting antimicrobial properties of extracts, essential oils, resins and various classes of compounds isolated from higher plants has been published in recent years; however, a comprehensive analysis of plant-derived antimicrobial ...
L. Kokoska +3 more
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Bioorganic & Medicinal Chemistry Letters, 2003
Compounds based on sordaricin were prepared via organometallic addition onto a fully protected sordaricin aldehyde. The fungal growth inhibition profiles for these compounds were established and the results are presented here. The synthesis of homologated sordaricin as well as ether and ester derivatives is presented, and structural rearrangement ...
John F. Barrett +11 more
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Compounds based on sordaricin were prepared via organometallic addition onto a fully protected sordaricin aldehyde. The fungal growth inhibition profiles for these compounds were established and the results are presented here. The synthesis of homologated sordaricin as well as ether and ester derivatives is presented, and structural rearrangement ...
John F. Barrett +11 more
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Expert Opinion on Drug Metabolism & Toxicology, 2019
Introduction: Therapeutic drug monitoring (TDM) has been shown to optimize the management of invasive fungal infections (IFIs), particularly for select antifungal agents with a well-defined exposure–response relationship and an unpredictable ...
Jamie John +3 more
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Introduction: Therapeutic drug monitoring (TDM) has been shown to optimize the management of invasive fungal infections (IFIs), particularly for select antifungal agents with a well-defined exposure–response relationship and an unpredictable ...
Jamie John +3 more
semanticscholar +1 more source
The Indian Journal of Pediatrics, 2004
Invasive fungal infections have evolved into significant causes of morbidity and mortality in premature infants, immunocompromised children, and patients receiving immunosuppressive agents. Since the discovery in 1955, amphotericin B has been the cornerstone of antifungal treatment.
Walid Abuhammour, Eyassu Habte-Gaber
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Invasive fungal infections have evolved into significant causes of morbidity and mortality in premature infants, immunocompromised children, and patients receiving immunosuppressive agents. Since the discovery in 1955, amphotericin B has been the cornerstone of antifungal treatment.
Walid Abuhammour, Eyassu Habte-Gaber
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Journal of Agricultural and Food Chemistry, 2018
Certain types of nanoparticles, especially zinc oxide nanoparticles (ZnONPs), are widely reported to be capable of the inhibition of harmful bacteria, yeasts, and filamentous fungi. The unique physicochemical and biological properties of ZnONPs also make
Qi Sun, Jianmei Li, T. Le
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Certain types of nanoparticles, especially zinc oxide nanoparticles (ZnONPs), are widely reported to be capable of the inhibition of harmful bacteria, yeasts, and filamentous fungi. The unique physicochemical and biological properties of ZnONPs also make
Qi Sun, Jianmei Li, T. Le
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Resistance to Antifungal Agents
Pediatric Clinics of North America, 1995The marked increase in the number of patients with AIDS and other forms of immunocompromise has resulted in the emergence of fungi as predominant pathogens in many institutions. Unfortunately, with the widespread use of antifungal agents to combat these infections, reports of resistance to antifungal agents have proliferated. In the present environment,
Margaret K. Hostetter, Gregory P. DeMuri
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Alkylated Piperazines and Piperazine-Azole Hybrids as Antifungal Agents.
Journal of Medicinal Chemistry, 2018The extensive use of fluconazole (FLC) and other azole drugs has caused the emergence and rise of azole-resistant fungi. The fungistatic nature of FLC in combination with toxicity concerns have resulted in an increased demand for new azole antifungal ...
Nishad Thamban Chandrika +5 more
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