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Antigens, Antigenicity, and Immunogenicity
2015The initiation of an immune response requires the interaction between T cells, B cells, and antigen-presenting cells (APCs), which form central components of almost all immune responses, and antigens, substances recognized as foreign by the immune system. The ability of an antigen to combine with antibody reflects the property of antigenicity.
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Antigen-antigen receptor interactions
Current Opinion in Structural Biology, 1991Abstract The genetic basis of antigen receptor diversity is understood for both B and T cell systems. Structural aspects of five specific antibody-antigen interactions have also been described. During the past year, new data comparing the structures of liganded and unliganded antibodies have given support to the hypothesis that there exists a ...
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Antigenic Determinants of Carcinoembryonic Antigen
Scandinavian Journal of Immunology, 1978Radioimmunoassays for carcinoembryonic antigen (CEA) have been established using a variety of different antisera raised in goat, monkey, rabbit, guinea pig and rat. The extent to which different antigens compete for antibodies in the sera has been estimated.
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TWO ANTIGENIC SPECIFICITIES IN THE AUSTRALIA ANTIGEN
Australian Journal of Experimental Biology and Medical Science, 1971SummaryTwo antigenic specificities have been detected in Australia antigens identified in Melbourne. One specificity was common to all antigens studied, the other was observed in approximately 50% of patients with Au‐positive acute viral hepatitis and also in all of a group of antigen‐positive institutionalized Mongols.In patients with acute viral ...
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Antigens Related to Carcinoembryonic Antigen [PDF]
G. Sundblad+3 more
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Journal of Allergy and Clinical Immunology, 1978
tide in electrophoretic mobility with these antigens, slides were cut in small segments and eluted, and the eluate was tested for biological activity. The results showed that maximal histamine-sensitizing activity, leukocytosis-promoting activity, and adjuvant activity for reaginic antibody were present in fraction 6.
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tide in electrophoretic mobility with these antigens, slides were cut in small segments and eluted, and the eluate was tested for biological activity. The results showed that maximal histamine-sensitizing activity, leukocytosis-promoting activity, and adjuvant activity for reaginic antibody were present in fraction 6.
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1981
Publisher Summary This chapter summarizes the current picture of polyoma T antigens, including their structure, the regions of the viral genome coding for them, and their possible roles in cell transformation. Polyoma T antigens are viral-coded proteins found in infected or transformed cells, detected by immunofluorescence or immunoprecipitation ...
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Publisher Summary This chapter summarizes the current picture of polyoma T antigens, including their structure, the regions of the viral genome coding for them, and their possible roles in cell transformation. Polyoma T antigens are viral-coded proteins found in infected or transformed cells, detected by immunofluorescence or immunoprecipitation ...
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