Results 31 to 40 of about 4,782 (211)

The Lake Victoria Island Intervention Study on Worms and Allergy-related diseases (LaVIISWA): study protocol for a randomised controlled trial. [PDF]

, 2015
BACKGROUND: The Hygiene Hypothesis proposes that infection exposure protects against inflammatory conditions. Helminths possess allergen-like molecules and may specifically modulate allergy-related immunological pathways to inhibit responses which ...
Akello, Mirriam, Elliott, Alison M, Kabagenyi, Joyce, Kabuubi, Prossy, Kaweesa, James, Kizindo, Robert, Kizito, Dennison, LaVIISWA trial team, Muhangi, Lawrence, Nakazibwe, Esther, Nampijja, Margaret, Namutebi, Milly, Nerima, Barbara, Oduru, Gloria, Tukahebwa, Edridah, Verweij, Jaco J, Webb, Emily L   +16 more
core   +1 more source

Effective antigen presentation to helper T cells by human eosinophils [PDF]

, 2016
Although eosinophils are inflammatory cells, there is increasing attention on their immunomodulatory roles. For example, murine eosinophils can present antigen to CD4+ T helper (Th) cells, but it remains unclear whether human eosinophils also have this ...
Akdis, Akuthota, Akuthota, Beninati, Blanchard, Blaylock, Cairns, Celestin, Charbonnier, Devereux, Floyd, Fujisawa, Hammad, Hansel, Hansel, Hinz, Lacy, Liu, Lucey, Mawhorter, Mawhorter, Mazzarella, Patel, Percopo, Rijt, Robinson, Rosenberg, Shakib, Shi, Sukati, Till, Trompette, Unanue, Wang, Wierenga, Woerly, Wynn   +36 more
core   +2 more sources

Th17 responses are not altered by natural exposure to seasonal allergens in pollen-sensitive patients [PDF]

, 2016
Background: Allergic rhinitis affects 10–30 % of the global population and this number is likely to increase in the forthcoming years. Moreover, it commonly co-exists with allergic asthma as a chronic allergic respiratory syndrome. While the involvement
Czesnikiewicz-Guzik, Marta, Jasiewicz-Honkisz, Barbara, Maciag, Joanna, Matusik, Pawel T., Mikolajczyk, Tomasz, Osmenda, Grzegorz, Sagan, Agnieszka, Schramm, Agata, Siedlinski, Mateusz, Sliwa, Tomasz, Wilk, Grzegorz   +10 more
core   +3 more sources

Hyposensitization with Dermatophagoides pteronyssinus Antigen: Trial in Asthma Induced by House Dust [PDF]

BMJ, 1971
A double-blind clinical trial of hyposensitization with aqueous extracts of Dermatophagoides pteronyssinus (the house-dust mite) and human skin scales showed a substantial improvement in symptoms in 11 asthmatics allergic to house dust treated with the D. pteronyssinus extract and a reduction in their need for other therapy. Five patients were well for
openaire   +2 more sources

Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]

, 2011
Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Brüske, Irene, Flohrs, Katrin, Heinrich, Joachim, Rzehak, Peter, Thiering, Elisabeth, Wichmann, Heinz-Erich   +5 more
core   +1 more source

Effects of Sequential Dermatophagoides Pteronyssinus Antigen Stimulation on Anatomy and Physiology of the Larynx [PDF]

Ear, Nose & Throat Journal, 2009
The goal of this investigation was to study the effects of sequential dust mite antigen stimulation on the appearance and function of the larynx. To that end, we designed a randomized, placebo-controlled, double-blind, prospective analysis of adults who had tested positive for perennial dust mite allergy. The larynx of patients who received the active
James P, Dworkin, Patrick M, Reidy, Robert J, Stachler, John H, Krouse   +3 more
openaire   +2 more sources

Validation of a food frequency questionnaire for children and adolescents aged 4 to 11 years living in Salvador, Bahia.

, 2012
OBJECTIVE: To assess the validity of a food frequency questionnaire (FFQ) by applying it to children and adolescents living in Salvador, Bahia. METHODS: The validity of this FFQ with 98 food items was investigated among 108 children and adolescents who ...
Assis, AMO, Barreto, ML, D'Innocenzo, S, Dourado, LS, Matos, SMA, Oliveira, NS, Prado, MS, Rodrigues, LC, Santos, CAST   +8 more
core   +2 more sources

IgA response in serum and gut secretion in sensitized mice fed with the dust mite Dermatophagoides pteronyssinus extract

Brazilian Journal of Medical and Biological Research, 2004
Induced oral tolerance to mucosal-exposed antigens in immunized animals is of particular interest for the development of immunotherapeutic approaches to human allergic diseases.
M. Maciel, A.E. Fusaro, C.R. Oliveira, E.A. Futata, A.J.S. Duarte, M.N. Sato   +5 more
doaj   +1 more source

Human T cell responses to recombinant mite antigens of Dermatophagoides farinae [PDF]

Clinical and Experimental Immunology, 1997
SUMMARY We studied T cell responses to four glutathione S transferase (GST)-fused mite antigens prepared in our laboratory using peripheral blood lymphocytes from mite-sensitive patients with bronchial asthma. Of the four recombinant antigens, purified GST-Mag3 had the strongest ability to cause patients' lymphocytes to proliferate, and ...
S, Fujii, K, Ono, S, Shigeta, T, Jyo, U, Yamashita   +4 more
openaire   +2 more sources

Safety of 300IR house dust mite sublingual tablet from pooled clinical trial and post-marketing data

World Allergy Organization Journal
Background: The 300IR house dust mite (HDM) sublingual immunotherapy (SLIT) tablet is approved for treatment of HDM-induced allergic rhinitis (AR).
Margitta Worm, MD, Pascal Demoly, MD, PhD, Yoshitaka Okamoto, MD, PhD, Carmen Vidal, MD, PhD, Katia Daghildjian, PharmD, PhD, Kwok Yan, MD, Thomas B. Casale, MD, Karl-Christian Bergmann, MD, PhD   +7 more
doaj   +1 more source