Results 31 to 40 of about 2,895 (167)
Mast Cells in Host Defense Against Cutaneous Staphylococcus aureus Infection
Impact of S. aureus epicutaneous sensitization models on mast cell function in vivo. D. farinae and Staphylococcal enterotoxin B (SEB) activate Trpv1+ Tac1+ nociceptors to trigger the release of substance P (SP), which promotes mast cell degranulation through Mrgprb2. S.
Hannah Dychtenberg +3 more
wiley +1 more source
Age at Onset of Asthma and Allergen Sensitization Early in Life
Background: Epidemiological evidence indicates that the age at onset of asthma and allergen sensitization in early life is decreasing in people from Western countries. To explore latent trends, we conducted a retrospective examination of the age at onset
Masahiko Kato +3 more
doaj +1 more source
Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan +8 more
wiley +1 more source
Edible Insect Allergens: An Emerging Food Safety Challenge
Allergic responses to edible insects arise via two main pathways: cross‐reactivity with homologous arthropod allergens and primary sensitization to edible insect proteins, both leading to IgE‐mediated immune activation. ABSTRACT Edible insects are increasingly promoted as sustainable protein sources; however, their allergenic potential remains a ...
Changqi Liu +5 more
wiley +1 more source
ABSTRACT Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread musculoskeletal pain, often accompanied by fatigue, sleep disturbance, and cognitive symptoms. Although several treatment options are available, no curative therapy has been established.
Hyuk Soon Kim +3 more
wiley +1 more source
Spray‐dried xylo‐oligosaccharide‐rich extract derived from olive pit endocarps was assessed for potential cross‐reactivity using in vitro ELISA and in silico approaches. The ELISA tests indicated potential cross‐reactivities with nuts (hazelnut, almond, pistachio, peanut), gluten, and milk in certain batches.
Maame Ekua Manful +4 more
wiley +1 more source
Background Skin prick testing is the most important diagnostic tool to detect immunoglobulin E-mediated allergic diseases. With increase in the number of allergy tests performed in India, it is imperative to know the potency of indigenous extracts in ...
Devasahayam J. Christopher BSc, DTCD, DNB, FICS, FAPSR, FRCP(Glasg), FCCP +6 more
doaj +1 more source
BackgroundSulphidoleukotrienes (slt) are important mediators in allergic diseases that are synthesized after allergen‐specific stimulation.ObjectivesThe aim of this study is to determine in vitro slt production after allergen‐specific (Dermatophagoides pteronyssinus) stimulus of peripheral blood leucocytes and to observe whether histamine release in ...
M, Ferrer +3 more
openaire +2 more sources
Background: In dogs with atopic dermatitis (AD), allergen testing is often timed to pollen exposure. However, data on seasonal effects on intradermal testing (IDT) and allergen‐specific immunoglobulin (Ig)E serology (SAT) are limited. Objectives: To evaluate the seasonal effects on IDT and SAT results in dogs with AD by comparing aeroallergen test ...
Jade Faucher +3 more
wiley +1 more source
Sema3E‐plexinD1 Axis Is a Modulator of Foxp3+ Regulatory T‐Cells in House Dust Mite Model of Asthma
Airway epithelial‐derived Sema3E enhances both the number and proliferation of Foxp3+ regulatory T (Treg) cells in an acute model of asthma. Mechanistically, deletion of PlexinD1, the receptor for Sema3E, specifically in Foxp3+ cells was associated with a breakdown in immune regulation in this model.
Mojdeh Matloubi +6 more
wiley +1 more source

