Results 271 to 280 of about 156,998 (310)
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Recognition of cluster of differentiation 1 antigens by human CD4−CD8>− cytolytic T lymphocyte
Nature, 1989Human cluster-of-differentiation 1 (CD1) is a family of cell surface glycoproteins of unknown function expressed on immature thymocytes, epidermal Langerhans cells and a subset of B lymphocytes. Three homologous proteins, CD1a, b and c, have been defined serologically, and the CD1 gene locus on human chromosome 1 contains five potential CD1 genes ...
S, Porcelli +5 more
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Expression of T cell differentiation antigens and Ia on rat cytotoxic T lymphocytes.
The Journal of Immunology, 1982Abstract Study of lymphocyte subsets has been facilitated by the detection of various surface markers that are related to distinct functions. We have explored the use of affinity methods for separation of large quantities (10(8)) of rat cells and used this technique to identify surface markers of cytotoxic T lymphocytes. Splenocytes from
A J, Duarte, C B, Carpenter, T B, Strom
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[Antigen recognition and differentiation of T lymphocytes].
Hematology and cell therapy, 1998During their intrathymic development, T lymphocytes acquire the ability to recognize myriads of antigens bound to self major histocompatibility molecules. This property is linked to the activation at early stages of thymic development of the biosynthesis of the antigen recognition receptors, the T cell receptors.
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The Journal of Immunology, 1980
Abstract There is considerable controversy regarding the cell lineage of killer (K) or effector cells in ADCC isolated from the “null” cell subpopulation (ER-sIg-) in human blood. Null cells were examined for the presence of T cell antigens by using a fluorescein-conjugated anti-T cell xenoantiserum (AMT).
C M, Balch +3 more
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Abstract There is considerable controversy regarding the cell lineage of killer (K) or effector cells in ADCC isolated from the “null” cell subpopulation (ER-sIg-) in human blood. Null cells were examined for the presence of T cell antigens by using a fluorescein-conjugated anti-T cell xenoantiserum (AMT).
C M, Balch +3 more
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The Journal of Immunology, 1991
Abstract Alloreactive CTL raised against HLA-A2 Ag often display heterogeneous recognition of HLA-A2+ target cells. This heterogeneity has been found to reflect structural polymorphism among the corresponding target Ag, thus defining HLA-A2 subtypes. A previous study (van der Poel et al. 1986. Human Immunol.
A R, Castaño +3 more
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Abstract Alloreactive CTL raised against HLA-A2 Ag often display heterogeneous recognition of HLA-A2+ target cells. This heterogeneity has been found to reflect structural polymorphism among the corresponding target Ag, thus defining HLA-A2 subtypes. A previous study (van der Poel et al. 1986. Human Immunol.
A R, Castaño +3 more
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Differential Ras signaling via the antigen receptor and IL-2 receptor in primary T lymphocytes
Biochemical and Biophysical Research Communications, 2003Ras can become activated via multiple distinct receptors in T lymphocytes. However, mechanistic studies of Ras signaling in normal T cells have been hampered by the lack of an efficient technology for gene transfer into resting post-thymic cells. We have overcome this limitation by utilizing adenoviral transduction of T cells from Coxsackie/adenovirus ...
Marks, Reinhard +5 more
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Leukemia Research, 1986
There are clones of myeloid leukemic cells that can be induced to differentiate in vitro and in vivo by normal macrophage and granulocyte differentiation-inducing protein MGI-2 (= DF). The differentiation of these myeloid leukemic cells in vivo is regulated by a cell mediated immune response which requires T lymphocytes.
J, Lotem, A, Ben-Nun, L, Sachs
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There are clones of myeloid leukemic cells that can be induced to differentiate in vitro and in vivo by normal macrophage and granulocyte differentiation-inducing protein MGI-2 (= DF). The differentiation of these myeloid leukemic cells in vivo is regulated by a cell mediated immune response which requires T lymphocytes.
J, Lotem, A, Ben-Nun, L, Sachs
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Exogenous and endogenous antigens are differentially presented by mast cells to CD4+ T lymphocytes
European Journal of Immunology, 1996AbstractIn the present work, we explored the cytokine‐dependent regulation of bone marrow‐derived mast cell (BMMC) antigen‐presenting cell (APC) function, and co‐stimulation requirements, and analyzed the nature of antigens presented to T cells. We observed an up‐regulation of the APC function of mast cells induced by granulocyte/macrophage‐colony ...
P, Frandji +5 more
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Veterinary immunology and immunopathology, 1991
The 14 mAbs representing workshop cluster 1 recognise a 215/300 kDa antigen expressed on a subpopulation of lymphocytes which express low levels of CD5 but are negative for other B and T cell markers defined by workshop antibodies. Separate studies with cDNA probes for bovine CD3 and T cell receptor indicate that these lymphocytes are gamma/delta T ...
W I, Morrison, W C, Davis
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The 14 mAbs representing workshop cluster 1 recognise a 215/300 kDa antigen expressed on a subpopulation of lymphocytes which express low levels of CD5 but are negative for other B and T cell markers defined by workshop antibodies. Separate studies with cDNA probes for bovine CD3 and T cell receptor indicate that these lymphocytes are gamma/delta T ...
W I, Morrison, W C, Davis
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Critical Reviews™ in Immunology, 1998
The pattern of lymphocyte traffic and migration in vivo is a composite of constitutive recirculation and transient changes induced by interaction with antigen. Naive T lymphocytes in their basal, unstimulated state continuously recirculate throughout the entire host, poised to react to specific antigens that they are programmed to recognize.
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The pattern of lymphocyte traffic and migration in vivo is a composite of constitutive recirculation and transient changes induced by interaction with antigen. Naive T lymphocytes in their basal, unstimulated state continuously recirculate throughout the entire host, poised to react to specific antigens that they are programmed to recognize.
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