Results 101 to 110 of about 1,322,361 (357)

Characterization of CD56+ dendritic-like cells: a normal counterpart of blastic plasmacytoid dendritic cell neoplasm? [PDF]

open access: yesPLoS ONE, 2013
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy. Plasmacytoid DCs (pDCs), which are defined as lineage marker (Lin)(-)HLA-DR(+)CD56(-)CD123(+)CD11c(-) cells, are considered to be the normal counterpart of BPDCNs ...
Yohei Osaki   +15 more
doaj   +1 more source

Mathematical modeling to elucidate brain tumor abrogation by immunotherapy with T11 target structure

open access: yes, 2015
T11 Target structure (T11TS), a membrane glycoprotein isolated from sheep erythrocytes, reverses the immune suppressed state of brain tumor induced animals by boosting the functional status of the immune cells.
Banerjee, Sandip   +2 more
core   +2 more sources

Umbilico-placental antigens and malignant neoplasms.

open access: yesThe Bulletin of Tokyo Medical and Dental University, 1972
Serological reactions between anti-human placental tissue antiserum and 584 human sera from patients of various diseases and conditions have been tested using the micro-Ouchterlony method. Relatively high incidence of positive reaction was noted with cases of malignant tumours (57.5%), leukaemia (63.6%), pregnancy (77.8%), myocardial infarction (41.2%),
Wataru MORI, Hideo ASAKAWA
openaire   +1 more source

A reappraisal of the value of carcinoembryonic antigen in the management of patients with various neoplasms

open access: yesJournal of British Surgery, 1979
Summary Eight hundred and eight patients with histologically proved malignant disease had carcinoembryonic antigen (CEA) estimations performed at the time of tissue diagnosis. An elevated level was found in 384 of 518 patients with gastrointestinal neoplasms (74 per cent) and in 162 of 290 patients with other neoplasms (56 per cent).
Colin R. Mackie   +3 more
openaire   +3 more sources

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

open access: yesMolecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi   +6 more
wiley   +1 more source

Affinity Discrimination in B cells in Response to Membrane Antigen Requires Kinetic Proofreading [PDF]

open access: yesarXiv, 2010
B cells signaling in response to antigen is proportional to antigen affinity, a process known as affinity discrimination. Recent research suggests that B cells can acquire antigen in membrane-bound form on the surface of antigen-presenting cells (APCs), with signaling being initiated within a few seconds of B cell/APC contact.
arxiv  

Molecular genetic analysis of three AIDS-associated neoplasms of uncertain lineage demonstrates their B-cell derivation and the possible pathogenetic role of the Epstein-Barr virus.

open access: yesBlood, 1989
Each of three individuals with acquired immunodeficiency syndrome (AIDS) developed a pleomorphic malignant neoplasm in which a precise histopathologic diagnosis could not be rendered. In each case, the tumor cells expressed leukocyte common antigen and a
D. Knowles   +3 more
semanticscholar   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Role of CD1A and HSP60 in the antitumoral response of oesophageal cancer

open access: yesOncology Reviews, 2011
Oesophageal cancer (OC) is one of the most common and severe forms of tumor. A wider knowledge of molecular mechanisms which lead to a normal epithelium becoming a neoplasm may reveal new strategies to improve treatment and outcome of this disease.
Simona Corrao   +6 more
doaj   +2 more sources

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