Results 321 to 330 of about 1,329,225 (354)
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Managing paraneoplastic neurological disorders.
The Oncologist, 2006Paraneoplastic neurological syndromes (PNS) are remote effects of cancer that are not caused by invasion of the tumor or its metastases. Immunologic factors appear important in the pathogenesis of PNS because antineuronal autoantibodies and T-cell ...
J. D. de Beukelaar, P. A. Sillevis Smitt
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American Journal of Reproductive Immunology, 1980
ABSTRACT: The genetic makeup of an individual may determine the capacity of the individual to combat successfully cancer and other disease states, eg abnormal pregnancies, abortions, infertility, and preeclampsia. These factors appear to be based upon the individual's immunogenetics, as histocompatibility‐restricted T‐cell cytotoxicity may be ...
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ABSTRACT: The genetic makeup of an individual may determine the capacity of the individual to combat successfully cancer and other disease states, eg abnormal pregnancies, abortions, infertility, and preeclampsia. These factors appear to be based upon the individual's immunogenetics, as histocompatibility‐restricted T‐cell cytotoxicity may be ...
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Chronic lymphocytic leukemia. Recent advances in biology and treatment.
Annals of Internal Medicine, 1985Chronic lymphocytic leukemia is a hematologic neoplasm characterized by proliferation and accumulation of mature-appearing lymphocytes. Most cases involve a clonal proliferation of B lymphocytes.
R. Gale, K. Foon
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Expression pattern of CD45 RA/RO isoformic antigens in T‐lineage neoplasms
American Journal of Hematology, 1995AbstractThe expression of CD45 RA/RO antigen was investigated in neoplasms including cases expressing CD7 antigen as the sole pan‐T antigen (n = 8), T‐lineage acute lymphoblastic leukemia (ALL)/lymphoblastic lymphoma (LBL) at various stages of differentiation (n = 32), peripheral stage T‐lineage leukemia (n = 10) and adult T‐cell leukemia (ATL) (n = 14)
Yoneda N +4 more
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Demonstration of tissue-specific antigens shared by normal pancreas and pancreatic neoplasms
Experientia, 1983Xenoantiserum raised against extracts of normal hamster pancreas, after absorption with normal tissues, reacted specifically with normal hamster and human pancreas by immunodiffusion. Absorbed antiserum also reacted with hamster and human pancreatic carcinoma but not with other neoplasms. Immunization of hamsters with normal pancreas extracts prevented
W F Sindelar, A R Dresdale, N A Hadley
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The Expression of Surface Antigen Leu 1 by Ocular Adnexal Lymphoid Neoplasms
American Journal of Ophthalmology, 1982Leu 1 is a surface membrane antigen expressed by benign systemic T cells, most cases of B-cell-derived chronic lymphocytic leukemia, and approximately one half of the systemic B-cell lymphomas. Benign systemic B cells are Leu 1-. Our studies showed that the percentage of Leu 1+ cells was essentially the same as the percentage of OKT3+E+ (T) cells in ...
Frederick A. Jakobiec +3 more
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Analysis of the B‐cell repertoire against antigens expressed by human neoplasms
Immunological Reviews, 2002Summary: The screening of tumor‐derived expression libraries for antigens detected by high‐titer immunoglobulin G antibodies from the sera of patients with cancer by SEREX (serological identification of antigens by recombinant expression cloning) allows a systematic search for antigens of human cancers.
Frank Neumann +4 more
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Gastroenterology, 1983
Radioimmunodetection of colorectal cancer was evaluated in 51 patients by injecting 131I-labeled goat antibody immunoglobulin G against carcinoembryonic antigen and performing total-body photoscans with a gamma scintillation camera 24 and 48 h later. The scintigrams were then processed by computer to subtract the images of the 99mTc-serum albumin and ...
E. Edmund Kim +4 more
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Radioimmunodetection of colorectal cancer was evaluated in 51 patients by injecting 131I-labeled goat antibody immunoglobulin G against carcinoembryonic antigen and performing total-body photoscans with a gamma scintillation camera 24 and 48 h later. The scintigrams were then processed by computer to subtract the images of the 99mTc-serum albumin and ...
E. Edmund Kim +4 more
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Proliferating cell nuclear antigen expression in central nervous system neoplasms
Virchows Archiv A Pathological Anatomy and Histopathology, 1991Proliferating cell nuclear antigen (PCNA) is a cell-cycle-regulated protein, which can be demonstrated in routinely fixed specimens. Studies on various tissues, cell cultures and neoplasms have shown that PCNA labelling index (LI) correlates with flow cytometry, tritiated thymidine LI, bromodeoxyuridine (BrdU) incorporation and Ki67 LI.
B. Polio +8 more
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Immunological Approaches to the Study of Viral Antigens Associated with Neoplasms
1969Advances in tumor virology and tumor immunology during the past 6 years or so have been characterized by 2 major achievements. One was the demonstration that in some SV40-induced tumors the entire viral genome may persist in the transformed cells in a non-infectious and non-antigenic state (1). The other landmark was the discovery in most virus-induced
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