Emerging Therapeutic Strategies for Lung Cancer: The Role of Immunotherapy and HPV-Targeted Cancer Vaccines. [PDF]
Bhaliya K, Anwer M, Wei MQ.
europepmc +1 more source
Hit-and-run hypothesis: revisiting the impact of EBV in malignancies. [PDF]
Mangiaterra T +8 more
europepmc +1 more source
Recent advances in discovery and functional analysis of the small proteins and microRNA expressed by polyomaviruses. [PDF]
Saribas AS, Jensen LE, Safak M.
europepmc +1 more source
Novel anti-tumor strategies: targeting the crosstalk between cancer stem cells and cancer-associated fibroblasts to resist drug resistance. [PDF]
Shen Y +8 more
europepmc +1 more source
Metabolic hijackers: how viral proteins redefine host cell landscapes. [PDF]
Hafner A, Mokry RL, Purdy JG, Wobus CE.
europepmc +1 more source
Possible association between polyomaviruses and gastrointestinal complications: a narrative review. [PDF]
Shadbash P +5 more
europepmc +1 more source
Antigenic and transforming properties of the DB strain of the human polyomavirus BK virus
Virology, 1990The analysis of the antigenic and transforming properties of the DB strain of the human polyomavirus BK Virus [BKV(DB)] is presented. Two genomes were molecularly cloned from a single virus preparation and were shown to represent viable virus; one clone [pBKV(DB)dl82] contained an 82 nucleotide deletion in the regulatory region relative to the second ...
Richard J Frisque, D L Walker
exaly +3 more sources
Phosphatidylinositol metabolism in cells transformed by polyomavirus middle T antigen
Journal of Virology, 1990Associated with the middle T antigen of polyomavirus is a novel phosphatidylinositol (PtdIns) kinase activity which phosphorylates PtdIns at the D-3 position of the inositol ring. We have undertaken an analysis of myo-[3H]inositol-containing compounds in a panel of NIH 3T3 cell lines stably transfected with transforming and nontransforming middle T ...
E T, Ulug +3 more
openaire +2 more sources
AbstractPolyomavirus (Py) encodes a potent oncogene, the middle T antigen (MT), that induces cell transformation by binding to and activating several cytoplasmic proteins which take part in transduction of growth factors‐induced mitogenic signal to the nucleus.
Sheila Maria Brochado, Winnischofer +2 more
openaire +2 more sources
We have found that lysis of mouse embryo cells infected with the polyomavirus host range transformation-defective (hr-t) mutant NG59 under gentle conditions that avoid ionic detergents results in detectable NG59-encoded middle tumor antigen (MTAg) associated with pp60c-src. This MTAg-pp60c-src complex could be immunoprecipitated from NG59-infected cell
J B, Bolen, M A, Israel
openaire +2 more sources

